Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy von Charych, Deborah, Khalili, Samira, Dixit, Vidula, Kirk, Peter, Chang, Thomas, Langowski, John, Rubas, Werner, Doberstein, Stephen K, Eldon, Michael, Hoch, Ute, Zalevsky, Jonathan

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Wnt5a–Ror–Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis von Ho, Hsin-Yi Henry, Susman, Michael W., Bikoff, Jay B., Ryu, Yun Kyoung, Jonas, Andrea M., Hu, Linda, Kuruvilla, Rejji, Greenberg, Michael Eldon

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Nonclinical pharmacokinetics and activity of etirinotecan pegol (NKTR-102), a long-acting topoisomerase 1 inhibitor, in multiple cancer models von Hoch, Ute, Staschen, Carl-Michael, Johnson, Randall K., Eldon, Michael A.

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Comparative bioavailability of inhaled treprostinil administered as LIQ861 and Tyvaso® in healthy subjects von Roscigno, Robert F., Vaughn, Toby, Parsley, Ed, Hunt, Thomas, Eldon, Michael A., Rubin, Lewis J.

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Safety, Tolerability, and Pharmacokinetics of RT234 (Vardenafil Inhalation Powder): A First-in-Human, Ascending Single- and Multiple-Dose Study in Healthy Subjects von Eldon, Michael A, Parsley, Edwin L, Maurer, Mari, Tarara, Thomas E, Okikawa, Jerry, Weers, Jeffry G

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The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle von Kamizaki, Koki, Doi, Ryosuke, Hayashi, Makoto, Saji, Takeshi, Kanagawa, Motoi, Toda, Tatsushi, Fukada, So-ichiro, Ho, Hsin-Yi Henry, Greenberg, Michael Eldon, Endo, Mitsuharu, Minami, Yasuhiro

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Human Abuse Potential of the New Opioid Analgesic Molecule NKTR-181 Compared with Oxycodone von Webster, Lynn, Henningfield, Jack, Buchhalter, August R, Siddhanti, Suresh, Lu, Lin, Odinecs, Aleksandrs, Di Fonzo, Carlo J, Eldon, Michael A

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Clinical pharmacokinetics and pharmacodynamics of inhaled insulin von PATTON, John S, BUKAR, Julie G, ELDON, Michael A

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NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer von Adkins, Chris E, Nounou, Mohamed I, Hye, Tanvirul, Mohammad, Afroz S, Terrell-Hall, Tori, Mohan, Neel K, Eldon, Michael A, Hoch, Ute, Lockman, Paul R

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Etirinotecan pegol administration is associated with lower incidences of neutropenia compared to irinotecan administration von Sy, S. Kenneth, Sweeney, Theresa D., Ji, Chunmei, Hoch, Ute, Eldon, Michael A.

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Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors von Sy, Sherwin K. B., Chia, Yen Lin, Gordi, Toufigh, Hoch, Ute, Eldon, Michael A.

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Human Abuse Potential of Oral NKTR-181 in Recreational Opioid Users: A Randomized, Double-Blind, Crossover Study von Ge, Xue, Henningfield, Jack E, Siddhanti, Suresh, Jobes, Janet, Lu, Lin, Xie, Sunny, Ziola, Margaret, Kelsh, Debra, Vince, Bradley, Di Fonzo, Carlo J, Tagliaferri, Mary, Zalevsky, Jonathan, Doberstein, Stephen K, Hoch, Ute, Eldon, Michael A

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EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding von Robichaux, Michael A., Chenaux, George, Ho, Hsin-Yi Henry, Soskis, Michael J., Dravis, Christopher, Kwan, Kenneth Y., Šestan, Nenad, Greenberg, Michael Eldon, Henkemeyer, Mark, Cowan, Christopher W.

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A Multicenter, Phase I, Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of Etirinotecan Pegol in Patients with Refractory Solid Tumors von JAMESON, Gayle S, HAMM, John T, HINSHAW, Loana, JOTTE, Robert, ROSEN, Lee S, HOCH, Ute, ELDON, Michael A, MEDVE, Robert, SCHROEDER, Katrina, WHITE, Erica, VON HOFF, Daniel D, WEISS, Glen J, ALEMANY, Carlos, ANTHONY, Stephen, BASCHE, Michele, RAMANATHAN, Ramesh K, BORAD, Mitesh J, TIBES, Raoul, COHN, Allen

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Safety, tolerability, pharmacokinetics, and pharmacodynamic effects of naloxegol at peripheral and central nervous system receptors in healthy male subjects: A single ascending-dos... von Eldon, Michael A., Kugler, Alan R., Medve, Robert A., Bui, Khanh, Butler, Kathleen, Sostek, Mark

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Pharmacokinetics and Tolerability of Amikacin Administered as BAY41-6551 Aerosol in Mechanically Ventilated Patients with Gram-Negative Pneumonia and Acute Renal Failure von LUYT, Charles-Edouard, ELDON, Michael A, STASS, Heino, GRIBBEN, Dennis, CORKERY, Kevin, CHASTRE, Jean

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A phase 2, randomized, double-blind, placebo-controlled, multicentre study to evaluate the efficacy and safety of pentosan polysulfate sodium in treating subjects with mucopolysacc... von Giugliani, Roberto, Gravance, Curtis, Krishnan, Ravi, Eldon, Michael, Imperiale, Michael

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Safety, tolerability, and pharmacokinetics of multiple ascending doses of naloxegol von Eldon, Michael A., Kugler, Alan R., Medve, Robert A., Bui, Khanh, Butler, Kathleen, Sostek, Mark

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Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation von Floettmann, Eike, Bui, Khanh, Sostek, Mark, Payza, Kemal, Eldon, Michael

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Pharmacokinetics and Tolerability of BAY41-6551 in Subjects with Chronic Kidney Disease von STASS, Heino, CORKERY, Kevin, GRIBBEN, Dennis, ELDON, Michael A

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