Isolated unilateral ptosis as a complication of sinusitis: A case report and literature review von El Sayed Ahmad, Youssef, Kazemizadeh Gol, Mohammad Abraham

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A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy von Ronan, Baptiste, Flamand, Odile, Vescovi, Lionel, Dureuil, Christine, Durand, Laurence, Fassy, Florence, Bachelot, Marie-France, Lamberton, Annabelle, Mathieu, Magali, Bertrand, Thomas, Marquette, Jean-Pierre, El-Ahmad, Youssef, Filoche-Romme, Bruno, Schio, Laurent, Garcia-Echeverria, Carlos, Goulaouic, Hélène, Pasquier, Benoit

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Discovery of (2S)‑8-[(3R)‑3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro‑2H‑pyrimido[1,2‑a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor... von Pasquier, Benoit, El-Ahmad, Youssef, Filoche-Rommé, Bruno, Dureuil, Christine, Fassy, Florence, Abecassis, Pierre-Yves, Mathieu, Magali, Bertrand, Thomas, Benard, Tsiala, Barrière, Cédric, El Batti, Samira, Letallec, Jean-Philippe, Sonnefraud, Véronique, Brollo, Maurice, Delbarre, Laurence, Loyau, Véronique, Pilorge, Fabienne, Bertin, Luc, Richepin, Patrick, Arigon, Jérôme, Labrosse, Jean-Robert, Clément, Jacques, Durand, Florence, Combet, Romain, Perraut, Pierre, Leroy, Vincent, Gay, Frédéric, Lefrançois, Dominique, Bretin, François, Marquette, Jean-Pierre, Michot, Nadine, Caron, Anne, Castell, Christelle, Schio, Laurent, McCort, Gary, Goulaouic, Hélène, Garcia-Echeverria, Carlos, Ronan, Baptiste

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Evolution in the management of vestibular schwannoma: a single-center 15-year experience von El Sayed Ahmad, Youssef, Gallois, Yohan, Sol, Jean Christophe, Boetto, Sergio, Attal, Justine, Sabatier, Jean, Debs, Rachel, Deguine, Olivier, Marx, Mathieu

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Comparison of Postoperative Pain and Appetite in Pediatric Patients Undergoing Monopolar Tonsillotomy and Cold Steel Tonsillectomy von El Sayed Ahmad, Youssef, Moukarzel, Nabil, Nehme, Jade

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Pituitary apoplexy: a systematic review of non-gestational risk factors von Kajal, Smile, Ahmad, Youssef El Sayed, Halawi, Akaber, Gol, Mohammad Abraham Kazemizadeh, Ashley, William

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SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models von Shomali, Maysoun, Cheng, Jane, Sun, Fangxian, Koundinya, Malvika, Guo, Zhuyan, Hebert, Andrew T, McManus, Jessica, Levit, Mikhail N, Hoffmann, Dietmar, Courjaud, Albane, Arrebola, Rosalia, Cao, Hui, Pollard, Jack, Lee, Joon Sang, Besret, Laurent, Caron, Anne, Bangari, Dinesh S, Abecassis, Pierre-Yves, Schio, Laurent, El-Ahmad, Youssef, Halley, Frank, Tabart, Michel, Certal, Victor, Thompson, Fabienne, McCort, Gary, Filoche-Rommé, Bruno, Cheng, Hong, Garcia-Echeverria, Carlos, Debussche, Laurent, Bouaboula, Monsif

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Abstract P4-02-08: Amcenestrant in combination with CDK4/6 inhibitor palbociclib demonstrates synergistic anti-tumor activity in ER+ endocrine-resistant breast cancer xenograft mod... von Shomali, Maysoun, Guo, Zhuyan, Cheng, Jane, Sullivan, Amy, El-Ahmad, Youssef, Sun, Fangxian, Sidhu, Sukhvinder, Lee, Joon Sang, Cai, Hui, Pollard, Jack, Debussche, Laurent, Soria, Chris, Bouaboula, Monsif

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Discovery of 6‑(2,4-Dichlorophenyl)-5-[4-[(3S)‑1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro‑7H‑benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Es... von El-Ahmad, Youssef, Tabart, Michel, Halley, Frank, Certal, Victor, Thompson, Fabienne, Filoche-Rommé, Bruno, Gruss-Leleu, Florence, Muller, Claire, Brollo, Maurice, Fabien, Laurence, Loyau, Véronique, Bertin, Luc, Richepin, Patrick, Pilorge, Fabienne, Desmazeau, Pascal, Girardet, Chrystelle, Beccari, Sylvie, Louboutin, Audrey, Lebourg, Gilles, Le-Roux, Jacques, Terrier, Corinne, Vallée, François, Steier, Valérie, Mathieu, Magali, Rak, Alexey, Abecassis, Pierre-Yves, Vicat, Pascale, Benard, Tsiala, Bouaboula, Monsif, Sun, Fangxian, Shomali, Maysoun, Hebert, Andrew, Levit, Mikhail, Cheng, Hong, Courjaud, Albane, Ginesty, Celine, Perrault, Christelle, Garcia-Echeverria, Carlos, McCort, Gary, Schio, Laurent

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Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3 S )-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7 H -benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selectiv... von El-Ahmad, Youssef, Tabart, Michel, Halley, Frank, Certal, Victor, Thompson, Fabienne, Filoche-Rommé, Bruno, Gruss-Leleu, Florence, Muller, Claire, Brollo, Maurice, Fabien, Laurence, Loyau, Véronique, Bertin, Luc, Richepin, Patrick, Pilorge, Fabienne, Desmazeau, Pascal, Girardet, Chrystelle, Beccari, Sylvie, Louboutin, Audrey, Lebourg, Gilles, Le-Roux, Jacques, Terrier, Corinne, Vallée, François, Steier, Valérie, Mathieu, Magali, Rak, Alexey, Abecassis, Pierre-Yves, Vicat, Pascale, Benard, Tsiala, Bouaboula, Monsif, Sun, Fangxian, Shomali, Maysoun, Hebert, Andrew, Levit, Mikhail, Cheng, Hong, Courjaud, Albane, Ginesty, Celine, Perrault, Christelle, Garcia-Echeverria, Carlos, McCort, Gary, Schio, Laurent

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Abstract PS17-16: Sar439859, a novel selective estrogen receptor degrader (serd), demonstrates effective and broad antitumor activity in wild-type and mutant er-positive breast can... von Shomali, Maysoun, Sun, Fangxian, Levit, Mikhail, Pollard, Jack, Lee, Joon Sang, Schio, Laurent, El-Ahmad, Youssef, Soria, Chris, Cohen, Patrick, Debussche, Laurent, Bouaboula, Monsif

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Managing Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT): A Comprehensive Narrative Review of Therapeutic Horizons von El Sayed Ahmad, Youssef, Kajal, Smile, Halawi, Akaber

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Abstract 3452: Pre-clinical development of next generation selective estrogen receptor degrader - SAR439859 von Sun, Fangxian, Cheng, Jane, Sullivan, Amy, Malkova, Natalia, Shomali, Maysoun, McManus, Jesseca, Levit, Mikhail, Bangari, Dinesh, El-Ahmad, Youssef, Sidhu, Sukhvinder, Debussche, Laurent, Bouaboula, Monsif

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Optimization and Gram-Scale Preparation of S‑Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF3 Group von Barthelemy, Anne-Laure, Certal, Victor, Dagousset, Guillaume, Anselmi, Elsa, Bertin, Luc, Fabien, Laurence, Salgues, Bruno, Courtes, Philippe, Poma, Christian, El-Ahmad, Youssef, Magnier, Emmanuel

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Scalable Synthesis of (R,R)‑N,N‑Dibenzyl-2-fluorocyclohexan-1-amine with CsF under Hydrogen Bonding Phase-Transfer Catalysis von Vicini, Anna Chiara, Alozie, Diké-Michel, Courtes, Philippe, Roagna, Giulia, Aubert, Catherine, Certal, Victor, El-Ahmad, Youssef, Roy, Sébastien, Gouverneur, Véronique

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Optimization and Gram-Scale Preparation of S -Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF 3 Group von Barthelemy, Anne-Laure, Certal, Victor, Dagousset, Guillaume, Anselmi, Elsa, Bertin, Luc, Fabien, Laurence, Salgues, Bruno, Courtes, Philippe, Poma, Christian, El-Ahmad, Youssef, Magnier, Emmanuel

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Optimization and Gram-Scale Preparation of S -Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF 3 Group von Barthelemy, Anne-Laure, Certal, Victor, Dagousset, Guillaume, Anselmi, Elsa, Bertin, Luc, Fabien, Laurence, Salgues, Bruno, Courtes, Philippe, Poma, Christian, El-Ahmad, Youssef, Magnier, Emmanuel

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Discovery of (2 S )-8-[(3 R )-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2 H -pyrimido[1,2- a ]pyrimidin-6-one: A Novel Potent and Selective In... von Pasquier, Benoit, El-Ahmad, Youssef, Filoche-Rommé, Bruno, Dureuil, Christine, Fassy, Florence, Abecassis, Pierre-Yves, Mathieu, Magali, Bertrand, Thomas, Benard, Tsiala, Barrière, Cédric, El Batti, Samira, Letallec, Jean-Philippe, Sonnefraud, Véronique, Brollo, Maurice, Delbarre, Laurence, Loyau, Véronique, Pilorge, Fabienne, Bertin, Luc, Richepin, Patrick, Arigon, Jérôme, Labrosse, Jean-Robert, Clément, Jacques, Durand, Florence, Combet, Romain, Perraut, Pierre, Leroy, Vincent, Gay, Frédéric, Lefrançois, Dominique, Bretin, François, Marquette, Jean-Pierre, Michot, Nadine, Caron, Anne, Castell, Christelle, Schio, Laurent, McCort, Gary, Goulaouic, Hélène, Garcia-Echeverria, Carlos, Ronan, Baptiste

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Discovery and Optimization of Pyrimidone Indoline Amide PI3Kβ Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers von Certal, Victor, Carry, Jean-Christophe, Halley, Frank, Virone-Oddos, Angela, Thompson, Fabienne, Filoche-Rommé, Bruno, El-Ahmad, Youssef, Karlsson, Andreas, Charrier, Véronique, Delorme, Cécile, Rak, Alexey, Abecassis, Pierre-Yves, Amara, Céline, Vincent, Loïc, Bonnevaux, Hélène, Nicolas, Jean-Paul, Mathieu, Magali, Bertrand, Thomas, Marquette, Jean-Pierre, Michot, Nadine, Benard, Tsiala, Perrin, Marc-Antoine, Lemaitre, Olivier, Guerif, Stephane, Perron, Sébastien, Monget, Sylvie, Gruss-Leleu, Florence, Doerflinger, Gilles, Guizani, Houlfa, Brollo, Maurice, Delbarre, Laurence, Bertin, Luc, Richepin, Patrick, Loyau, Véronique, Garcia-Echeverria, Carlos, Lengauer, Christoph, Schio, Laurent

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Abstract 943: SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that demonstrates robust antitumor efficacy and limited cross-resistance in ER+ breast c... von Bouaboula, Monsif, Shomali, Maysoun, Cheng, Jane, Malkova, Natalia, Sun, Fangxian, Koundinya, Malvika, Guo, Zhuyan, Poirier, Stephane, Levit, Mikhail, Hoffman, Dietmar, Cao, Hui, Bestret, Laurent, Adrian, Francisco, Winter, Christoph, El-Ahmad, Youssef, Vincent, Sylvie, Halley, Frank, McCort, Gary, Schio, Laurent, Richon, Vicky, Cheng, Hong, Hsu, Karl, Soria, Chris, Cohen, Patrick, Lager, Joanne, Garcia-Echeverria, Carlos, Debussche, Laurent

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