Complex heatmaps reveal patterns and correlations in multidimensional genomic data von Gu, Zuguang, Eils, Roland, Schlesner, Matthias

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EnrichedHeatmap: an R/Bioconductor package for comprehensive visualization of genomic signal associations von Gu, Zuguang, Eils, Roland, Schlesner, Matthias, Ishaque, Naveed

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COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis von Chua, Robert Lorenz, Lukassen, Soeren, Trump, Saskia, Hennig, Bianca P., Wendisch, Daniel, Pott, Fabian, Debnath, Olivia, Thürmann, Loreen, Kurth, Florian, Völker, Maria Theresa, Kazmierski, Julia, Timmermann, Bernd, Twardziok, Sven, Schneider, Stefan, Machleidt, Felix, Müller-Redetzky, Holger, Maier, Melanie, Krannich, Alexander, Schmidt, Sein, Balzer, Felix, Liebig, Johannes, Loske, Jennifer, Suttorp, Norbert, Eils, Jürgen, Ishaque, Naveed, Liebert, Uwe Gerd, von Kalle, Christof, Hocke, Andreas, Witzenrath, Martin, Goffinet, Christine, Drosten, Christian, Laudi, Sven, Lehmann, Irina, Conrad, Christian, Sander, Leif-Erik, Eils, Roland

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One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy von Fricke, Franziska, Beaudouin, Joel, Eils, Roland, Heilemann, Mike

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Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy von Krieger, Teresa G., Le Blanc, Solange, Jabs, Julia, Ten, Foo Wei, Ishaque, Naveed, Jechow, Katharina, Debnath, Olivia, Leonhardt, Carl-Stephan, Giri, Anamika, Eils, Roland, Strobel, Oliver, Conrad, Christian

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NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing von Prager, Isabel, Liesche, Clarissa, van Ooijen, Hanna, Urlaub, Doris, Verron, Quentin, Sandström, Niklas, Fasbender, Frank, Claus, Maren, Eils, Roland, Beaudouin, Joël, Önfelt, Björn, Watzl, Carsten

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Cell segmentation-free inference of cell types from in situ transcriptomics data von Park, Jeongbin, Choi, Wonyl, Tiesmeyer, Sebastian, Long, Brian, Borm, Lars E., Garren, Emma, Nguyen, Thuc Nghi, Tasic, Bosiljka, Codeluppi, Simone, Graf, Tobias, Schlesner, Matthias, Stegle, Oliver, Eils, Roland, Ishaque, Naveed

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Optogenetic control of nuclear protein export von Niopek, Dominik, Wehler, Pierre, Roensch, Julia, Eils, Roland, Di Ventura, Barbara

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Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands von Haller, Florian, Bieg, Matthias, Will, Rainer, Körner, Cindy, Weichenhan, Dieter, Bott, Alexander, Ishaque, Naveed, Lutsik, Pavlo, Moskalev, Evgeny A., Mueller, Sarina K., Bähr, Marion, Woerner, Angelika, Kaiser, Birgit, Scherl, Claudia, Haderlein, Marlen, Kleinheinz, Kortine, Fietkau, Rainer, Iro, Heinrich, Eils, Roland, Hartmann, Arndt, Plass, Christoph, Wiemann, Stefan, Agaimy, Abbas

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Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity von Liu, Longqi, Liu, Chuanyu, Quintero, Andrés, Wu, Liang, Yuan, Yue, Wang, Mingyue, Cheng, Mengnan, Leng, Lizhi, Xu, Liqin, Dong, Guoyi, Li, Rui, Liu, Yang, Wei, Xiaoyu, Xu, Jiangshan, Chen, Xiaowei, Lu, Haorong, Chen, Dongsheng, Wang, Quanlei, Zhou, Qing, Lin, Xinxin, Li, Guibo, Liu, Shiping, Wang, Qi, Wang, Hongru, Fink, J. Lynn, Gao, Zhengliang, Liu, Xin, Hou, Yong, Zhu, Shida, Yang, Huanming, Ye, Yunming, Lin, Ge, Chen, Fang, Herrmann, Carl, Eils, Roland, Shang, Zhouchun, Xu, Xun

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Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19 von Trump, Saskia, Lukassen, Soeren, Anker, Markus S., Chua, Robert Lorenz, Liebig, Johannes, Thürmann, Loreen, Corman, Victor Max, Binder, Marco, Loske, Jennifer, Klasa, Christina, Krieger, Teresa, Hennig, Bianca P., Messingschlager, Marey, Pott, Fabian, Kazmierski, Julia, Twardziok, Sven, Albrecht, Jan Philipp, Eils, Jürgen, Hadzibegovic, Sara, Lena, Alessia, Heidecker, Bettina, Bürgel, Thore, Steinfeldt, Jakob, Goffinet, Christine, Kurth, Florian, Witzenrath, Martin, Völker, Maria Theresa, Müller, Sarah Dorothea, Liebert, Uwe Gerd, Ishaque, Naveed, Kaderali, Lars, Sander, Leif-Erik, Drosten, Christian, Laudi, Sven, Eils, Roland, Conrad, Christian, Landmesser, Ulf, Lehmann, Irina

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Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing von Hovestadt, Volker, Jones, David T. W., Picelli, Simone, Wang, Wei, Kool, Marcel, Northcott, Paul A., Sultan, Marc, Stachurski, Katharina, Ryzhova, Marina, Warnatz, Hans-Jörg, Ralser, Meryem, Brun, Sonja, Bunt, Jens, Jäger, Natalie, Kleinheinz, Kortine, Erkek, Serap, Weber, Ursula D., Bartholomae, Cynthia C., von Kalle, Christof, Lawerenz, Chris, Eils, Jürgen, Koster, Jan, Versteeg, Rogier, Milde, Till, Witt, Olaf, Schmidt, Sabine, Wolf, Stephan, Pietsch, Torsten, Rutkowski, Stefan, Scheurlen, Wolfram, Taylor, Michael D., Brors, Benedikt, Felsberg, Jörg, Reifenberger, Guido, Borkhardt, Arndt, Lehrach, Hans, Wechsler-Reya, Robert J., Eils, Roland, Yaspo, Marie-Laure, Landgraf, Pablo, Korshunov, Andrey, Zapatka, Marc, Radlwimmer, Bernhard, Pfister, Stefan M., Lichter, Peter

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Tagmentation-based whole-genome bisulfite sequencing von Wang, Qi, Gu, Lei, Adey, Andrew, Radlwimmer, Bernhard, Wang, Wei, Hovestadt, Volker, Bähr, Marion, Wolf, Stephan, Shendure, Jay, Eils, Roland, Plass, Christoph, Weichenhan, Dieter

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Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype von Wu, Yonghe, Fletcher, Michael, Gu, Zuguang, Wang, Qi, Costa, Barbara, Bertoni, Anna, Man, Ka-Hou, Schlotter, Magdalena, Felsberg, Jörg, Mangei, Jasmin, Barbus, Martje, Gaupel, Ann-Christin, Wang, Wei, Weiss, Tobias, Eils, Roland, Weller, Michael, Liu, Haikun, Reifenberger, Guido, Korshunov, Andrey, Angel, Peter, Lichter, Peter, Herrmann, Carl, Radlwimmer, Bernhard

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Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer von Ishaque, Naveed, Abba, Mohammed L., Hauser, Christine, Patil, Nitin, Paramasivam, Nagarajan, Huebschmann, Daniel, Leupold, Jörg Hendrik, Balasubramanian, Gnana Prakash, Kleinheinz, Kortine, Toprak, Umut H., Hutter, Barbara, Benner, Axel, Shavinskaya, Anna, Zhou, Chan, Gu, Zuguang, Kerssemakers, Jules, Marx, Alexander, Moniuszko, Marcin, Kozlowski, Miroslaw, Reszec, Joanna, Niklinski, Jacek, Eils, Jürgen, Schlesner, Matthias, Eils, Roland, Brors, Benedikt, Allgayer, Heike

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Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection von Hensel, Nina, Gu, Zuguang, Sagar, Wieland, Dominik, Jechow, Katharina, Kemming, Janine, Llewellyn-Lacey, Sian, Gostick, Emma, Sogukpinar, Oezlem, Emmerich, Florian, Price, David A., Bengsch, Bertram, Boettler, Tobias, Neumann-Haefelin, Christoph, Eils, Roland, Conrad, Christian, Bartenschlager, Ralf, Grün, Dominic, Ishaque, Naveed, Thimme, Robert, Hofmann, Maike

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SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals von Gassen, Nils C., Papies, Jan, Bajaj, Thomas, Emanuel, Jackson, Dethloff, Frederik, Chua, Robert Lorenz, Trimpert, Jakob, Heinemann, Nicolas, Niemeyer, Christine, Weege, Friderike, Hönzke, Katja, Aschman, Tom, Heinz, Daniel E., Weckmann, Katja, Ebert, Tim, Zellner, Andreas, Lennarz, Martina, Wyler, Emanuel, Schroeder, Simon, Richter, Anja, Niemeyer, Daniela, Hoffmann, Karen, Meyer, Thomas F., Heppner, Frank L., Corman, Victor M., Landthaler, Markus, Hocke, Andreas C., Morkel, Markus, Osterrieder, Nikolaus, Conrad, Christian, Eils, Roland, Radbruch, Helena, Giavalisco, Patrick, Drosten, Christian, Müller, Marcel A.

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Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells von Niopek, Dominik, Benzinger, Dirk, Roensch, Julia, Draebing, Thomas, Wehler, Pierre, Eils, Roland, Di Ventura, Barbara

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Web-based design and analysis tools for CRISPR base editing von Hwang, Gue-Ho, Park, Jeongbin, Lim, Kayeong, Kim, Sunghyun, Yu, Jihyeon, Yu, Eunchong, Kim, Sang-Tae, Eils, Roland, Kim, Jin-Soo, Bae, Sangsu

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Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival Mitophagy versus Apoptosis von Zhu, Yanyan, Massen, Stefan, Terenzio, Marco, Lang, Verena, Chen-Lindner, Silu, Eils, Roland, Novak, Ivana, Dikic, Ivan, Hamacher-Brady, Anne, Brady, Nathan R.

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