Modulators of 14-3‑3 Protein–Protein Interactions von Stevers, Loes M, Sijbesma, Eline, Botta, Maurizio, MacKintosh, Carol, Obsil, Tomas, Landrieu, Isabelle, Cau, Ylenia, Wilson, Andrew J, Karawajczyk, Anna, Eickhoff, Jan, Davis, Jeremy, Hann, Michael, O’Mahony, Gavin, Doveston, Richard G, Brunsveld, Luc, Ottmann, Christian

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The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells von Paolino, Magdalena, Choidas, Axel, Wallner, Stephanie, Pranjic, Blanka, Uribesalgo, Iris, Loeser, Stefanie, Jamieson, Amanda M., Langdon, Wallace Y., Ikeda, Fumiyo, Fededa, Juan Pablo, Cronin, Shane J., Nitsch, Roberto, Schultz-Fademrecht, Carsten, Eickhoff, Jan, Menninger, Sascha, Unger, Anke, Torka, Robert, Gruber, Thomas, Hinterleitner, Reinhard, Baier, Gottfried, Wolf, Dominik, Ullrich, Axel, Klebl, Bert M., Penninger, Josef M.

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A cell-based chemical-genetic screen for amino acid stress response inhibitors reveals torins reverse stress kinase GCN2 signaling von Brüggenthies, Johanna B., Fiore, Alessandra, Russier, Marion, Bitsina, Christina, Brötzmann, Julian, Kordes, Susanne, Menninger, Sascha, Wolf, Alexander, Conti, Elena, Eickhoff, Jan E., Murray, Peter J.

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A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations von Hutterer, Corina, Eickhoff, Jan, Milbradt, Jens, Korn, Klaus, Zeitträger, Isabel, Bahsi, Hanife, Wagner, Sabrina, Zischinsky, Gunther, Wolf, Alexander, Degenhart, Carsten, Unger, Anke, Baumann, Matthias, Klebl, Bert, Marschall, Manfred

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Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer von Lücking, Ulrich, Scholz, Arne, Lienau, Philip, Siemeister, Gerhard, Kosemund, Dirk, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Meyer, Kirstin, Prelle, Katja, Denner, Karsten, Bömer, Ulf, Schäfer, Martina, Eis, Knut, Valencia, Ray, Ince, Stuart, von Nussbaum, Franz, Mumberg, Dominik, Ziegelbauer, Karl, Klebl, Bert, Choidas, Axel, Nussbaumer, Peter, Baumann, Matthias, Schultz‐Fademrecht, Carsten, Rühter, Gerd, Eickhoff, Jan, Brands, Michael

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Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency von Schütz, Martin, Wangen, Christina, Sommerer, Mona, Kögler, Melanie, Eickhoff, Jan, Degenhart, Carsten, Klebl, Bert, Naing, Zin, Egilmezer, Ece, Hamilton, Stuart T., Rawlinson, William D., Sticht, Heinrich, Marschall, Manfred

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Cyclin-Dependent Kinase 7 Controls mRNA Synthesis by Affecting Stability of Preinitiation Complexes, Leading to Altered Gene Expression, Cell Cycle Progression, and Survival of Tum... von Kelso, Timothy W. R., Baumgart, Karen, Eickhoff, Jan, Albert, Thomas, Antrecht, Claudia, Lemcke, Sarah, Klebl, Bert, Meisterernst, Michael

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Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers von Wild, Markus, Karner, Dubravka, Eickhoff, Jan, Wagner, Sabrina, Kicuntod, Jintawee, Chang, William, Barry, Peter, Jonjić, Stipan, Lenac Roviš, Tihana, Marschall, Manfred

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Development of a live cell assay for real-time monitoring the interactions between the Hippo pathway components 14-3-3 and TAZ von Andlovic, Blaž, Wolf, Alexander, Hiltmann, Malgorzata, Klebl, Bert M., Eickhoff, Jan, Ottmann, Christian

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Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo von Reinhardt, Lydia, Kordes, Susanne, Reinhardt, Peter, Glatza, Michael, Baumann, Matthias, Drexler, Hannes C.A., Menninger, Sascha, Zischinsky, Gunther, Eickhoff, Jan, Fröb, Claudia, Bhattarai, Prabesh, Arulmozhivarman, Guruchandar, Marrone, Lara, Janosch, Antje, Adachi, Kenjiro, Stehling, Martin, Anderson, Eric N., Abo-Rady, Masin, Bickle, Marc, Pandey, Udai Bhan, Reimer, Michell M., Kizil, Caghan, Schöler, Hans R., Nussbaumer, Peter, Klebl, Bert, Sterneckert, Jared L.

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An Antiherpesviral Host-Directed Strategy Based on CDK7 Covalently Binding Drugs: Target-Selective, Picomolar-Dose, Cross-Virus Reactivity von Yu, DongHoon, Wagner, Sabrina, Schütz, Martin, Jeon, Yeejin, Seo, Mooyoung, Kim, Jaeseung, Brückner, Nadine, Kicuntod, Jintawee, Tillmanns, Julia, Wangen, Christina, Hahn, Friedrich, Kaufer, Benedikt B, Neipel, Frank, Eickhoff, Jan, Klebl, Bert, Nam, Kiyean, Marschall, Manfred

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Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target von Tillmanns, Julia, Häge, Sigrun, Borst, Eva Maria, Wardin, Julia, Eickhoff, Jan, Klebl, Bert, Wagner, Sabrina, Wangen, Christina, Hahn, Friedrich, Socher, Eileen, Marschall, Manfred

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ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysis von Cibir, Zülal, Hassel, Jacqueline, Sonneck, Justin, Kowitz, Lennart, Beer, Alexander, Kraus, Andreas, Hallekamp, Gabriel, Rosenkranz, Martin, Raffelberg, Pascal, Olfen, Sven, Smilowski, Kamil, Burkard, Roman, Helfrich, Iris, Tuz, Ali Ata, Singh, Vikramjeet, Ghosh, Susmita, Sickmann, Albert, Klebl, Anne-Kathrin, Eickhoff, Jan Eike, Klebl, Bert, Seidl, Karsten, Chen, Jianxu, Grabmaier, Anton, Viga, Reinhard, Gunzer, Matthias

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Characterization of the Antibacterial Activity of Quinone-Based Compounds Originating from the Alnumycin Biosynthetic Gene Cluster of a Streptomyces Isolate von Sagurna, Leonie, Heinrich, Sascha, Kaufmann, Lara-Sophie, Rückert-Reed, Christian, Busche, Tobias, Wolf, Alexander, Eickhoff, Jan, Klebl, Bert, Kalinowski, Jörn, Bandow, Julia E

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Recruitment of cyclin-dependent kinase 9 to nuclear compartments during cytomegalovirus late replication: importance of an interaction between viral pUL69 and cyclin T1 von FEICHTINGER, Sabine, STAMMINGER, Thomas, MÜLLER, Regina, GRAF, Laura, KLEBL, Bert, EICKHOFF, Jan, MARSCHALL, Manfred

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Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity von Rechter, Sabine, Scott, Gillian M., Eickhoff, Jan, Zielke, Katrin, Auerochs, Sabrina, Müller, Regina, Stamminger, Thomas, Rawlinson, William D., Marschall, Manfred

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Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling von GODL, Klaus, GRUSS, Oliver J, KERI, György, MÜLLER, Stefan, COTTON, Matt, ULLRICH, Axel, DAUB, Henrik, EICKHOFF, Jan, WISSING, Josef, BLENCKE, Stephanie, WEBER, Martina, DEGEN, Heidrun, BREHMER, Dirk, ÖRFI, Laszlo, HORVATH, Zoltan

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A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening von Kaufmann, Johanna, Blum, Nina Kathleen, Nagel, Falko, Schuler, Anna, Drube, Julia, Degenhart, Carsten, Engel, Julian, Eickhoff, Jan Eicke, Dasgupta, Pooja, Fritzwanker, Sebastian, Guastadisegni, Maria, Schulte, Clemens, Miess-Tanneberg, Elke, Maric, Hans Michael, Spetea, Mariana, Kliewer, Andrea, Baumann, Matthias, Klebl, Bert, Reinscheid, Rainer K., Hoffmann, Carsten, Schulz, Stefan

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The Role of RIP2 in p38 MAPK Activation in the Stressed Heart von Jacquet, Sebastien, Nishino, Yasuhiro, Kumphune, Sarawut, Sicard, Pierre, Clark, James E., Kobayashi, Koichi S., Flavell, Richard A., Eickhoff, Jan, Cotten, Matt, Marber, Michael S.

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IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization von Andlovic, Blaž, Heilmann, Geronimo, Ninck, Sabrina, Andrei, Sebastian A., Centorrino, Federica, Higuchi, Yusuke, Kato, Nobuo, Brunsveld, Luc, Arkin, Michelle, Menninger, Sascha, Choidas, Axel, Wolf, Alexander, Klebl, Bert, Kaschani, Farnusch, Kaiser, Markus, Eickhoff, Jan, Ottmann, Christian

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