Pharmacogenomics and individualized drug therapy von Eichelbaum, Michel, Ingelman-Sundberg, Magnus, Evans, William E

Volltext

Activity Levels of Tamoxifen Metabolites at the Estrogen Receptor and the Impact of Genetic Polymorphisms of Phase I and II Enzymes on Their Concentration Levels in Plasma von Mürdter, TE, Schroth, W, Bacchus‐Gerybadze, L, Winter, S, Heinkele, G, Simon, W, Fasching, PA, Fehm, T, Eichelbaum, M, Schwab, M, Brauch, H

Volltext

Predictive Value of Known and Novel Alleles of CYP2B6 for Efavirenz Plasma Concentrations in HIV‐infected Individuals von Rotger, M, Tegude, H, Colombo, S, Cavassini, M, Furrer, H, Décosterd, L, Blievernicht, J, Saussele, T, Günthard, H F, Schwab, M, Eichelbaum, M, Telenti, A, Zanger, U M

Volltext

Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer von Saladores, P, Mürdter, T, Eccles, D, Chowbay, B, Zgheib, N K, Winter, S, Ganchev, B, Eccles, B, Gerty, S, Tfayli, A, Lim, J S L, Yap, Y S, Ng, R C H, Wong, N S, Dent, R, Habbal, M Z, Schaeffeler, E, Eichelbaum, M, Schroth, W, Schwab, M, Brauch, H

Volltext

Functional Polymorphisms of the Human Multidrug-Resistance Gene: Multiple Sequence Variations and Correlation of One Allele with P-Glycoprotein Expression and Activity in vivo von Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H. P., Brockmoller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M., Brinkmann, U.

Volltext

Polymorphic Organic Anion Transporting Polypeptide 1B1 is a Major Determinant of Repaglinide Pharmacokinetics von Niemi, Mikko, Backman, Janne T., Kajosaari, Lauri I., Leathart, Julian B., Neuvonen, Mikko, Daly, Ann K., Eichelbaum, Michel, Kivistö, Kari T., Neuvonen, Pertti J.

Volltext

X-ray-assisted formation of gold nanoparticles in soda lime silicate glass: suppressed Ostwald ripening von Tatchev, D, Hoell, A, Eichelbaum, M, Rademann, K

Volltext

Evidence for Exchange Coupled Electrons and Holes in MgO after Oxidative Activation of CH4: A Multifrequency Transient Nutation EPR Study von Schwach, P, Eichelbaum, M, Schlögl, R, Risse, T, Dinse, K.-P

Volltext

ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation von HAUSER, Ingeborg A, SCHAEFFELER, Elke, GEIGER, Helmut, EICHELBAUM, Michel, SCHWAB, Matthias, GAUER, Stefan, SCHEUERMANN, Ernst H, WEGNER, Binytha, GOSSMANN, Jan, ACKERMANN, Hanns, SEIDL, Christian, HOCHER, Berthold, ZANGER, Ulrich M

Volltext

A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects von RAIMUNDO, Sebastian, TOSCANO, Claudia, KLEIN, Kathrin, FISCHER, Joachim, GRIESE, Ernst-Ulrich, EICHELBAUM, Michel, SCHWAB, Matthias, ZANGER, Ulrich M

Volltext

P‐glycoprotein‐mediated intestinal and biliary digoxin transport in humans von Drescher, Siegfried, Glaeser, Hartmut, Mürdter, Thomas, Hitzl, Monika, Eichelbaum, Michel, Fromm, Martin F.

Volltext

Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid‐lowering efficacy of multiple‐dose pravastatin von Igel, Michael, Arnold, Katja A., Niemi, Mikko, Hofmann, Ute, Schwab, Matthias, Lütjohann, Dieter, Bergmann, Klaus, Eichelbaum, Michel, Kivistö, Kari T.

Volltext

The Impact of Thyroid Disease on the Regulation, Expression, and Function of ABCB1 (MDR1/P Glycoprotein) and Consequences for the Disposition of Digoxin von Burk, O, Brenner, S S, Hofmann, U, Tegude, H, Igel, S, Schwab, M, Eichelbaum, M, Alscher, M D

Volltext

Selective Induction of Human Hepatic Cytochromes P450 2B6 and 3A4 by Metamizole von Saussele, T, Burk, O, Blievernicht, J K, Klein, K, Nussler, A, Nussler, N, Hengstler, J G, Eichelbaum, M, Schwab, M, Zanger, U M

Volltext

Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes von Glaeser, H., Drescher, S., Eichelbaum, M., Fromm, M. F.

Volltext

Three-photon-induced luminescence of gold nanoparticles embedded in and located on the surface of glassy nanolayers von Eichelbaum, M, Schmidt, B E, Ibrahim, H, Rademann, K

Volltext

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype von Gradhand, U, Lang, T, Schaeffeler, E, Glaeser, H, Tegude, H, Klein, K, Fritz, P, Jedlitschky, G, Kroemer, H K, Bachmakov, I, Anwald, B, Kerb, R, Zanger, U M, Eichelbaum, M, Schwab, M, Fromm, M F

Volltext

The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions von Kivisto, KT, Kroemer, HK, Eichelbaum, M.

Volltext

Polymorphisms in the ABC drug transporter gene MDR1 von Brinkmann, U, Eichelbaum, M

Volltext

Safe treatment of thiopurine S-methyltransferase deficient Crohn’s disease patients with azathioprine von Kaskas, B A, Louis, E, Hindorf, U, Schaeffeler, E, Deflandre, J, Graepler, F, Schmiegelow, K, Gregor, M, Zanger, U M, Eichelbaum, M, Schwab, M

Volltext