Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants von Lefkowitz, Roy B., PhD, Tynan, John A., PhD, Liu, Tong, PhD, Wu, Yijin, PhD, Mazloom, Amin R., PhD, Almasri, Eyad, MS, Hogg, Grant, MS, Angkachatchai, Vach, PhD, Zhao, Chen, PhD, Grosu, Daniel S., MD, McLennan, Graham, MS, Ehrich, Mathias, MD

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Noninvasive prenatal screening for fetal trisomies 21, 18, 13 and the common sex chromosome aneuploidies from maternal blood using massively parallel genomic sequencing of DNA von Porreco, Richard P., MD, Garite, Thomas J., MD, Maurel, Kimberly, MSN, CNS, Marusiak, Barbara, MS, CRM, Ehrich, Mathias, MD, van den Boom, Dirk, PhD, Deciu, Cosmin, MS, Bombard, Allan, MD

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Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting von Ehrich, Mathias, MD, Deciu, Cosmin, MSc, Zwiefelhofer, Tricia, Tynan, John A., DPhil, Cagasan, Lesley, MSc, Tim, Roger, DPhil, Lu, Vivian, McCullough, Ron, DPhil, McCarthy, Erin, Nygren, Anders O.H., DPhil, Dean, Jarrod, Tang, Lin, DPhil, Hutchison, Don, MSc, Lu, Tim, DPhil, Wang, Huiquan, DPhil, Angkachatchai, Vach, DPhil, Oeth, Paul, MSc, Cantor, Charles R., DPhil, Bombard, Allan, MD, van den Boom, Dirk, DPhil

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DNA sequencing of maternal plasma to detect Down syndrome: An international clinical validation study von Palomaki, Glenn E, Kloza, Edward M, Lambert-Messerlian, Geralyn M, Haddow, James E, Neveux, Louis M, Ehrich, Mathias, van den Boom, Dirk, Bombard, Allan T, Deciu, Cosmin, Grody, Wayne W, Nelson, Stanley F, Canick, Jacob A

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Determination of fetal DNA fraction from the plasma of pregnant women using sequence read counts von Kim, Sung K., Hannum, Gregory, Geis, Jennifer, Tynan, John, Hogg, Grant, Zhao, Chen, Jensen, Taylor J., Mazloom, Amin R., Oeth, Paul, Ehrich, Mathias, van den Boom, Dirk, Deciu, Cosmin

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DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study von Palomaki, Glenn E., Deciu, Cosmin, Kloza, Edward M., Lambert-Messerlian, Geralyn M., Haddow, James E., Neveux, Louis M., Ehrich, Mathias, van den Boom, Dirk, Bombard, Allan T., Grody, Wayne W., Nelson, Stanley F., Canick, Jacob A.

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Oct4-Induced Pluripotency in Adult Neural Stem Cells von Kim, Jeong Beom, Sebastiano, Vittorio, Wu, Guangming, Araúzo-Bravo, Marcos J., Sasse, Philipp, Gentile, Luca, Ko, Kinarm, Ruau, David, Ehrich, Mathias, van den Boom, Dirk, Meyer, Johann, Hübner, Karin, Bernemann, Christof, Ortmeier, Claudia, Zenke, Martin, Fleischmann, Bernd K., Zaehres, Holm, Schöler, Hans R.

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Optimizing blood collection, transport and storage conditions for cell free DNA increases access to prenatal testing von Wong, David, Moturi, Sharmili, Angkachatchai, Vach, Mueller, Reinhold, DeSantis, Grace, van den Boom, Dirk, Ehrich, Mathias

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Quantitative High-Throughput Analysis of DNA Methylation Patterns by Base-Specific Cleavage and Mass Spectrometry von Mathias Ehrich, Nelson, Matthew R., Stanssens, Patrick, Zabeau, Marc, Triantafillos Liloglou, George Xinarianos, Cantor, Charles R., John K. Field, van den Boom, Dirk

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Noninvasive prenatal detection of sex chromosomal aneuploidies by sequencing circulating cell-free DNA from maternal plasma von Mazloom, Amin R., Džakula, Željko, Oeth, Paul, Wang, Huiquan, Jensen, Taylor, Tynan, John, McCullough, Ron, Saldivar, Juan-Sebastian, Ehrich, Mathias, van den Boom, Dirk, Bombard, Allan T., Maeder, Margo, McLennan, Graham, Meschino, Wendy, Palomaki, Glenn E., Canick, Jacob A., Deciu, Cosmin

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DNA sequencing of maternal plasma to identify Down syndrome and other trisomies in multiple gestations von Canick, Jacob A., Kloza, Edward M., Lambert-Messerlian, Geralyn M., Haddow, James E., Ehrich, Mathias, van den Boom, Dirk, Bombard, Allan T., Deciu, Cosmin, Palomaki, Glenn E.

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Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing von Linhart, Heinz G, Lin, Haijiang, Yamada, Yasuhiro, Moran, Eva, Steine, Eveline J, Gokhale, Sumita, Lo, Grace, Cantu, Erika, Ehrich, Mathias, He, Timothy, Meissner, Alex, Jaenisch, Rudolf

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Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice von Kansara, Maya, Tsang, Michael, Kodjabachian, Laurent, Sims, Natalie A, Trivett, Melanie K, Ehrich, Mathias, Dobrovic, Alexander, Slavin, John, Choong, Peter F M, Simmons, Paul J, Dawid, Igor B, Thomas, David M

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Quantitative DNA methylation predicts survival in adult acute myeloid leukemia von Bullinger, Lars, Ehrich, Mathias, Döhner, Konstanze, Schlenk, Richard F., Döhner, Hartmut, Nelson, Matthew R., van den Boom, Dirk

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Cytosine methylation profiling of cancer cell lines von Ehrich, Mathias, Turner, Julia, Gibbs, Peter, Lipton, Lara, Giovanneti, Mara, Cantor, Charles, van den Boom, Dirk

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High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasma von Jensen, Taylor J, Zwiefelhofer, Tricia, Tim, Roger C, Džakula, Željko, Kim, Sung K, Mazloom, Amin R, Zhu, Zhanyang, Tynan, John, Lu, Tim, McLennan, Graham, Palomaki, Glenn E, Canick, Jacob A, Oeth, Paul, Deciu, Cosmin, van den Boom, Dirk, Ehrich, Mathias

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Multiplexed analysis of circulating cell-free fetal nucleic acids for noninvasive prenatal diagnostic RHD testing von Tynan, John A., DPhil, Angkachatchai, Vach, DPhil, Ehrich, Mathias, MD, Paladino, Toni, DPhil, van den Boom, Dirk, DPhil, Oeth, Paul, MS

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Hypermethylation of Genes for Diagnosis and Risk Stratification of Prostate Cancer von Vanaja, Donkena Krishna, Ehrich, Mathias, Van den Boom, Dirk, Cheville, John C., Karnes, R. Jeffrey, Tindall, Donald J., Cantor, Charles R., Young, Charles Y.F.

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Stemness of the organ of Corti relates to the epigenetic status of Sox2 enhancers von Waldhaus, Jörg, Cimerman, Jelka, Gohlke, Henning, Ehrich, Mathias, Müller, Marcus, Löwenheim, Hubert

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Epithelial Progeny of Estrogen-Exposed Breast Progenitor Cells Display a Cancer-like Methylome von CHENG, Alfred S. L, CULHANE, Aedin C, NEPHEW, Kenneth P, YEATMAN, Timothy J, HUANG, Tim H.-M, CHAN, Michael W. Y, VENKATARAMU, Chinnambally R, EHRICH, Mathias, NASIR, Aejaz, RODRIGUEZ, Benjamin A. T, LIU, Joseph, YAN, Pearlly S, QUACKENBUSH, John

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