Development of [89Zr]Zr-hCD103.Fab01A and [68Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET von Fan, Xiaoyu, Ważyńska, Marta A., Kol, Arjan, Perujo Holland, Noemi, Fernandes, Bruna, van Duijnhoven, Sander M. J., Plat, Annechien, van Eenennaam, Hans, Elsinga, Philip H., Nijman, Hans W., de Bruyn, Marco

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APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment von Tai, Yu-Tzu, Acharya, Chirag, An, Gang, Moschetta, Michele, Zhong, Mike Y., Feng, Xiaoyan, Cea, Michele, Cagnetta, Antonia, Wen, Kenneth, van Eenennaam, Hans, van Elsas, Andrea, Qiu, Lugui, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.

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Helpless Priming Sends CD8 + T Cells on the Road to Exhaustion von Busselaar, Julia, Tian, Sun, van Eenennaam, Hans, Borst, Jannie

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CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment von Lei, Xin, Khatri, Indu, de Wit, Tom, de Rink, Iris, Nieuwland, Marja, Kerkhoven, Ron, van Eenennaam, Hans, Sun, Chong, Garg, Abhishek D., Borst, Jannie, Xiao, Yanling

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Human TLR10 is an anti-inflammatory pattern-recognition receptor von Oosting, Marije, Cheng, Shih-Chin, Bolscher, Judith M, Vestering-Stenger, Rachel, Plantinga, Theo S, Verschueren, Ineke C, Arts, Peer, Garritsen, Anja, van Eenennaam, Hans, Sturm, Patrick, Kullberg, Bart-Jan, Hoischen, Alexander, Adema, Gosse J, van der Meer, Jos W M, Netea, Mihai G, Joosten, Leo A B

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PD-1 Blockade Augments Th1 and Th17 and Suppresses Th2 Responses in Peripheral Blood From Patients With Prostate and Advanced Melanoma Cancer von DULOS, John, CARVEN, Gregory J, JACOBS, Joannes F. M, SCHALKEN, Jack A, OOSTERWIJK, Egbert, EENENNAAM, Hans Van, BOOTS, Annemieke M, BOXTEL, Susan J. Van, EVERS, Sabine, DRIESSEN-ENGELS, Lilian J. A, HOBO, Willemijn, GORECKA, Monika A, DE HAAN, Anton F. J, MULDERS, Peter, PUNT, Cornelis J. A

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Blockade of ErbB2 and PD-L1 using a bispecific antibody to improve targeted anti-ErbB2 therapy von Mittal, Deepak, Vijayan, Dipti, Neijssen, Joost, Kreijtz, Joost, Habraken, Maurice M. J. M., Van Eenennaam, Hans, Van Elsas, Andrea, Smyth, Mark J.

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Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα–CD47 innate immune checkpoint von Voets, Erik, Paradé, Marc, Lutje Hulsik, David, Spijkers, Sanne, Janssen, Wout, Rens, Joost, Reinieren-Beeren, Inge, van den Tillaart, Gilbert, van Duijnhoven, Sander, Driessen, Lilian, Habraken, Maurice, van Zandvoort, Peter, Kreijtz, Joost, Vink, Paul, van Elsas, Andrea, van Eenennaam, Hans

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Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies von Dang, Xibei, Guelen, Lars, Lutje Hulsik, David, Ermakov, Grigori, Hsieh, Edward J, Kreijtz, Joost, Stammen-Vogelzangs, Judith, Lodewijks, Imke, Bertens, Astrid, Bramer, Arne, Guadagnoli, Marco, Nazabal, Alexis, van Elsas, Andrea, Fischmann, Thierry, Juan, Veronica, Beebe, Amy, Beaumont, Maribel, van Eenennaam, Hans

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Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin von Kenny, Elaine F, Quinn, Susan R, Doyle, Sarah L, Vink, Paul M, van Eenennaam, Hans, O'Neill, Luke A J

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Single-cell intracellular epitope and transcript detection reveals signal transduction dynamics von Rivello, Francesca, van Buijtenen, Erik, Matuła, Kinga, van Buggenum, Jessie A.G.L., Vink, Paul, van Eenennaam, Hans, Mulder, Klaas W., Huck, Wilhelm T.S.

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770 ADU-1604, a novel CTLA-4 blocking antibody modulates pharmacodynamic markers in PD1 relapse/refractory melanoma patients von Oria de Rueda, Guillemo De Velasco, Rutkowski, Piotr, Maio, Michele, Arance, Ana Maria, Robert, Caroline, Chiarion-Sileni, Vanna, Marquez-Rodas, Ivan, Kundapur, Jessica, Villaudy, Julien, Eenennaam, Hans Van, Lassouw-Polman, Laura, Eggermont, Alexander

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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy von Guelen, Lars, Fischmann, Thierry O, Wong, Jerelyn, Mauze, Smita, Guadagnoli, Marco, Bąbała, Nikolina, Wagenaars, Jozef, Juan, Veronica, Rosen, David, Prosise, Winnie, Habraken, Maurice, Lodewijks, Imke, Gu, Danling, Stammen-Vogelzangs, Judith, Yu, Ying, Baker, Jeanne, Lutje Hulsik, David, Driessen-Engels, Lilian, Malashock, Dan, Kreijtz, Joost, Bertens, Astrid, de Vries, Evert, Bovens, Astrid, Bramer, Arne, Zhang, Yiwei, Wnek, Richard, Troth, Sean, Chartash, Elliot, Dobrenkov, Konstantin, Sadekova, Svetlana, van Elsas, Andrea, Cheung, Jason K, Fayadat-Dilman, Laurence, Borst, Jannie, Beebe, Amy M, Van Eenennaam, Hans

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Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases von Shang, Peng, Baarends, Willy M, Hoogerbrugge, Jos, Ooms, Marja P, van Cappellen, Wiggert A, de Jong, Antonius A.W, Dohle, Gert R, van Eenennaam, Hans, Gossen, Jan A, Grootegoed, J. Anton

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Mutations in the RNA Component of RNase MRP Cause a Pleiotropic Human Disease, Cartilage-Hair Hypoplasia von Ridanpää, Maaret, van Eenennaam, Hans, Pelin, Katarina, Chadwick, Robert, Johnson, Cheryl, Yuan, Bo, vanVenrooij, Walther, Pruijn, Ger, Salmela, Riika, Rockas, Susanna, Mäkitie, Outi, Kaitila, Ilkka, de la Chapelle, Albert

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Development of 89Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration von Kol, Arjan, Fan, Xiaoyu, Wazynska, Marta A., van Duijnhoven, Sander M.J., Giesen, Danique, Plat, Annechien, Van Eenennaam, Hans, Elsinga, Philip H., Nijman, Hans W., de Bruyn, Marco

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721 AT1412, a patient-derived CD9 antibody in preclinical development promoting tumor immune infiltration and inducing tumor rejection von Schotte, Remko, Villaudy, Julien, Kedde, Martijn, Pos, Wouter, Go, Daniel, Fatmawati, Christien, Moiset, Gemma, Yasuda, Etsuko, Cercel, Madalina, Frankin, Esmay, Hal, Susan van, Helden, Pauline van, Verdegaal, Els, Burg, Sjoerd van der, Spits, Hergen, Eenennaam, Hans van

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499 AT1636, a colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin von Beaumont, Tim, Kedde, Martijn, Merat, Sabrina, Kwakkenbos, Mark, Bartels, Lina, Berg, Dorien van der, Wagner, Koen, Bakker, Arjen, Maijoor, Kelly, Bohne, Martino, Bru, Camille, Kattler, Veronika, Claassen, Yvonne, Moiset, Gemma, Eenennaam, Hans Van, Roos, Victorine, Kallenberg, Frank, Medema, Jan, Hensbergen, Paul, Helden, Pauline van, Dekker, Evelien, Spits, Hergen

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CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism von Veninga, Henrike, Groot, Dorien M., McCloskey, Natalie, Owens, Bronwyn M., Dessing, Mark C., Verbeek, J. Sjef, Nourshargh, Sussan, Eenennaam, Hans, Boots, Annemieke M., Hamann, Jörg

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In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation von Vink, Paul M, Smout, Wendy M, Driessen-Engels, Lilian J, de Bruin, Alex M, Delsing, Dianne, Krajnc-Franken, Magda A, Jansen, Aswin J, Rovers, Eric F, van Puijenbroek, André A, Kaptein, Allard, Nolte, Martijn A, Garritsen, Anja, van Eenennaam, Hans

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