Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing von Edkins, Sarah, Santarius, Thomas, Goodhead, Ian, Edwards, Paul A W, Menzies, Andrew, Bignell, Graham R, Pleasance, Erin D, Stephens, Philip J, O'Meara, Sarah, Stebbings, Lucy A, Hardy, Claire, Brown, Clive, Li, Heng, Turner, Daniel J, Cox, Antony, Campbell, Peter J, Quail, Michael A, Teague, Jon W, Leroy, Catherine, Durbin, Richard, Clee, Christopher M, Futreal, P Andrew, Stratton, Michael R, Hurles, Matthew E

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NRG1 fusions in breast cancer von Howarth, Karen D., Mirza, Tashfina, Cooke, Susanna L., Chin, Suet-Feung, Pole, Jessica C., Turro, Ernest, Eldridge, Matthew D., Garcia, Raquel Manzano, Rueda, Oscar M., Boursnell, Chris, Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W.

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Complex multi-enhancer contacts captured by genome architecture mapping von Beagrie, Robert A., Scialdone, Antonio, Schueler, Markus, Kraemer, Dorothee C. A., Chotalia, Mita, Xie, Sheila Q., Barbieri, Mariano, de Santiago, Inês, Lavitas, Liron-Mark, Branco, Miguel R., Fraser, James, Dostie, Josée, Game, Laurence, Dillon, Niall, Edwards, Paul A. W., Nicodemi, Mario, Pombo, Ana

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Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity von Kim, Jiyoung, Villadsen, René, Sørlie, Therese, Fogh, Louise, Grønlund, Signe Z, Fridriksdottir, Agla J, Kuhn, Irene, Rank, Fritz, Wielenga, Vera Timmermans, Solvang, Hiroko, Edwards, Paul A. W, Børresen-Dale, Anne-Lise, Rønnov-Jessen, Lone, Bissell, Mina J, Petersen, Ole William

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Fusion genes and chromosome translocations in the common epithelial cancers von Edwards, Paul AW

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The relative timing of mutations in a breast cancer genome von Newman, Scott, Howarth, Karen D, Greenman, Chris D, Bignell, Graham R, Tavaré, Simon, Edwards, Paul A W

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Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes von Schulte, Ina, Batty, Elizabeth M, Pole, Jessica C M, Blood, Katherine A, Mo, Steven, Cooke, Susanna L, Ng, Charlotte, Howe, Kevin L, Chin, Suet-Feung, Brenton, James D, Caldas, Carlos, Howarth, Karen D, Edwards, Paul A W

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Re‐interpreting tumour behaviour and the tumour microenvironment as normal responses to tissue disorganisation von Edwards, Paul AW

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Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation von Mason, Bethany, Flach, Susanne, Teixeira, Felipe R., Manzano Garcia, Raquel, Rueda, Oscar M., Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W., Laman, Heike

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Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer von Santonja, Angela, Cooper, Wendy N, Eldridge, Matthew D, Edwards, Paul A W, Morris, James A, Edwards, Abigail R, Zhao, Hui, Heider, Katrin, Couturier, Dominique‐Laurent, Vijayaraghavan, Aadhitthya, Mennea, Paulius, Ditter, Emma‐Jane, Smith, Christopher G, Boursnell, Chris, Manzano García, Raquel, Rueda, Oscar M, Beddowes, Emma, Biggs, Heather, Sammut, Stephen‐John, Rosenfeld, Nitzan, Caldas, Carlos, Abraham, Jean E, Gale, Davina

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High-resolution array CGH clarifies events occurring on 8p in carcinogenesis von Cooke, Susanna L, Pole, Jessica C M, Chin, Suet-Feung, Ellis, Ian O, Caldas, Carlos, Edwards, Paul A W

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Sister chromatid junctions in the hyperthermophilic archaeon Sulfolobus solfataricus von Robinson, Nicholas P, Blood, Katherine A, McCallum, Simon A, Edwards, Paul AW, Bell, Stephen D

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A recurrent chromosome breakpoint in breast cancer at the NRG1/Neuregulin 1/Heregulin gene von HUANG, Huai-En, CHIN, Suet-Feung, GULLICK, William J, JACQUEMIER, Jocelyne, CALDAS, Carlos, CHAFFANET, Max, BIRNBAUM, Daniel, EDWARDS, Paul A. W, GINESTIER, Christophe, BARDOU, Valérie-Jeanne, ADELAÏDE, José, GOPALAKRISHNA IYER, N, GARCIA, Maria J, POLE, Jessica C, CALLAGY, Grace M, HEWITT, Stephen M

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Estimation of rearrangement phylogeny for cancer genomes von Greenman, Chris D, Pleasance, Erin D, Newman, Scott, Yang, Fengtang, Fu, Beiyuan, Nik-Zainal, Serena, Jones, David, Lau, King Wai, Carter, Nigel, Edwards, Paul A W, Futreal, P Andrew, Stratton, Michael R, Campbell, Peter J

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Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution von Bignell, Graham R, Santarius, Thomas, Pole, Jessica C M, Butler, Adam P, Perry, Janet, Pleasance, Erin, Greenman, Chris, Menzies, Andrew, Taylor, Sheila, Edkins, Sarah, Campbell, Peter, Quail, Michael, Plumb, Bob, Matthews, Lucy, McLay, Kirsten, Edwards, Paul A W, Rogers, Jane, Wooster, Richard, Futreal, P Andrew, Stratton, Michael R

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Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis von Paterson, Anna L, Weaver, Jamie M J, Eldridge, Matthew D, Tavaré, Simon, Fitzgerald, Rebecca C, Edwards, Paul A W

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The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer von Ng, Charlotte KY, Cooke, Susanna L, Howe, Kevin, Newman, Scott, Xian, Jian, Temple, Jillian, Batty, Elizabeth M, Pole, Jessica CM, Langdon, Simon P, Edwards, Paul AW, Brenton, James D

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Are breast cancers driven by fusion genes? von Edwards, Paul A W, Howarth, Karen D

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Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles von Howarth, Karen D, Pole, Jessica C M, Beavis, Juliet C, Batty, Elizabeth M, Newman, Scott, Bignell, Graham R, Edwards, Paul A W

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Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells von Little, Annette S, Balmanno, Kathryn, Sale, Matthew J, Newman, Scott, Dry, Jonathan R, Hampson, Mark, Edwards, Paul A W, Smith, Paul D, Cook, Simon J

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