Naturally Occurring Off-Switches for CRISPR-Cas9 von Pawluk, April, Amrani, Nadia, Zhang, Yan, Garcia, Bianca, Hidalgo-Reyes, Yurima, Lee, Jooyoung, Edraki, Alireza, Shah, Megha, Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.

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5'-Modifications improve potency and efficacy of DNA donors for precision genome editing von Ghanta, Krishna S, Chen, Zexiang, Mir, Aamir, Dokshin, Gregoriy A, Krishnamurthy, Pranathi M, Yoon, Yeonsoo, Gallant, Judith, Xu, Ping, Zhang, Xiao-Ou, Ozturk, Ahmet Rasit, Shin, Masahiro, Idrizi, Feston, Liu, Pengpeng, Gneid, Hassan, Edraki, Alireza, Lawson, Nathan D, Rivera-Pérez, Jaime A, Sontheimer, Erik J, Watts, Jonathan K, Mello, Craig C

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NmeCas9 is an intrinsically high-fidelity genome-editing platform von Amrani, Nadia, Gao, Xin D, Liu, Pengpeng, Edraki, Alireza, Mir, Aamir, Ibraheim, Raed, Gupta, Ankit, Sasaki, Kanae E, Wu, Tong, Donohoue, Paul D, Settle, Alexander H, Lied, Alexandra M, McGovern, Kyle, Fuller, Chris K, Cameron, Peter, Fazzio, Thomas G, Zhu, Lihua Julie, Wolfe, Scot A, Sontheimer, Erik J

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Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins von Lee, Jooyoung, Mir, Aamir, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Lou, Hannah E, Gainetdinov, Ildar, Pawluk, April, Ibraheim, Raed, Gao, Xin D, Liu, Pengpeng, Davidson, Alan R, Maxwell, Karen L, Sontheimer, Erik J

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CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro von Meijboom, Katharina E., Abdallah, Abbas, Fordham, Nicholas P., Nagase, Hiroko, Rodriguez, Tomás, Kraus, Carolyn, Gendron, Tania F., Krishnan, Gopinath, Esanov, Rustam, Andrade, Nadja S., Rybin, Matthew J., Ramic, Melina, Stephens, Zachary D., Edraki, Alireza, Blackwood, Meghan T., Kahriman, Aydan, Henninger, Nils, Kocher, Jean-Pierre A., Benatar, Michael, Brodsky, Michael H., Petrucelli, Leonard, Gao, Fen-Biao, Sontheimer, Erik J., Brown, Robert H., Zeier, Zane, Mueller, Christian

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Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing von Garcia, Bianca, Lee, Jooyoung, Edraki, Alireza, Hidalgo-Reyes, Yurima, Erwood, Steven, Mir, Aamir, Trost, Chantel N., Seroussi, Uri, Stanley, Sabrina Y., Cohn, Ronald D., Claycomb, Julie M., Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.

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A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing von Edraki, Alireza, Mir, Aamir, Ibraheim, Raed, Gainetdinov, Ildar, Yoon, Yeonsoo, Song, Chun-Qing, Cao, Yueying, Gallant, Judith, Xue, Wen, Rivera-Pérez, Jaime A., Sontheimer, Erik J.

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Type II‑C CRISPR-Cas9 Biology, Mechanism, and Application von Mir, Aamir, Edraki, Alireza, Lee, Jooyoung, Sontheimer, Erik J

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Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States von Sun, Wei, Yang, Jing, Cheng, Zhi, Amrani, Nadia, Liu, Chao, Wang, Kangkang, Ibraheim, Raed, Edraki, Alireza, Huang, Xue, Wang, Min, Wang, Jiuyu, Liu, Liang, Sheng, Gang, Yang, Yanhua, Lou, Jizhong, Sontheimer, Erik J., Wang, Yanli

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A Broad-Spectrum Inhibitor of CRISPR-Cas9 von Harrington, Lucas B., Doxzen, Kevin W., Ma, Enbo, Liu, Jun-Jie, Knott, Gavin J., Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Chen, Janice S., Cofsky, Joshua C., Kranzusch, Philip J., Sontheimer, Erik J., Davidson, Alan R., Maxwell, Karen L., Doudna, Jennifer A.

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CRISPRs from scratch von Edraki, Alireza, Sontheimer, Erik J.

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Targeted CRISPR delivery platforms von ILDAR, Gainetdinov, IBRAHEIM, Raed, SONTHEIMER, Erik Joseph, EDRAKI, Alireza, XUE, Wen, MIR, Aamir

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Targeted CRISPR Delivery Platforms von Xue, Wen, Mir, Aamir, Sontheimer, Erik J, Gainetdinov, Ildar, Edraki, Alireza, Ibraheim, Raed

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Targeted CRISPR delivery platforms von ILDAR, Gainetdinov, IBRAHEIM, Raed, SONTHEIMER, Erik Joseph, EDRAKI, Alireza, XUE, Wen, MIR, Aamir

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PROGRAMMABLE DNA BASE EDITING BY NME2CAS9-DEAMINASE FUSION PROTEINS von Mir, Aamir, Sontheimer, Erik J, Wolfe, Scot A, Liu, Pengpeng, Edraki, Alireza, Gao, Xin

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PROGRAMMABLE DNA BASE EDITING BY NME2CAS9-DEAMINASE FUSION PROTEINS von GAO, Xin, WOLFE, Scot, A, EDRAKI, Alireza, SONTHEIMER, Erik, J, MIR, Aamir, LIU, Pengpeng

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TARGETED CRISPR DELIVERY PLATFORMS von ILDAR, Gainetdinov, SONTHEIMER, Erik, Joseph, IBRAHEIM, Raed, EDRAKI, Alireza, XUE, Wen, MIR, Aamir

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PROGRAMMABLE DNA BASE EDITING BY NME2CAS9-DEAMINASE FUSION PROTEINS von GAO, Xin, SONTHEIMER, Erik, EDRAKI, Alireza, WOLFE, Scot, MIR, Aamir, LIU, Pengpeng

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Programmable DNA base editing by Nme2Cas9-deaminase fusion proteins von WOLFE, Scot A, GAO, Xin, EDRAKI, Alireza, SONTHEIMER, Erik J, MIR, Aamir, LIU, Pengpeng

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TARGETED CRISPR DELIVERY PLATFORMS von ILDAR, Gainetdinov, SONTHEIMER, Erik, Joseph, IBRAHEIM, Raed, EDRAKI, Alireza, XUE, Wen, MIR, Aamir

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