Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints von Edman, Karl, Hosseini, Ali, Bjursell, Magnus K., Aagaard, Anna, Wissler, Lisa, Gunnarsson, Anders, Kaminski, Tim, Köhler, Christian, Bäckström, Stefan, Jensen, Tina J., Cavallin, Anders, Karlsson, Ulla, Nilsson, Ewa, Lecina, Daniel, Takahashi, Ryoji, Grebner, Christoph, Geschwindner, Stefan, Lepistö, Matti, Hogner, Anders C., Guallar, Victor

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Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion von Bamberg, Krister, Johansson, Ulrika, Edman, Karl, William-Olsson, Lena, Myhre, Susanna, Gunnarsson, Anders, Geschwindner, Stefan, Aagaard, Anna, Björnson Granqvist, Anna, Jaisser, Frédéric, Huang, Yufeng, Granberg, Kenneth L, Jansson-Löfmark, Rasmus, Hartleib-Geschwindner, Judith

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AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double‐blind, efficacy, and safety study von Laar, Jacob M., Lei, Alejhandra, Safy‐Khan, Mary, Almquist, Joachim, Belfield, Graham, Edman, Karl, Öberg, Lisa, Angermann, Bastian R., Dillmann, Inken, Berntsson, Pia, Etal, Damla, Dainty, Ian, Astbury, Carol, Belvisi, Maria G., Nemes, Szilárd, Platt, Adam, Prothon, Susanne, Samuelsson, Sara, Svanberg, Petter, Keen, Christina, Jacobs, J. W. G., Kaan, Ellen, Tubergen, Astrid, Hermans, Kasper, Vonkeman, Harald, Moghadam, Marjan Ghiti, Gjertsson, Inger, Ekwall, Anna‐Karin, Kapetanovic, Meliha, Einarsson, Jon Thorkell, Axelsson, Lena T., Olsson, Richard, Myrbäck, Tove Hegelund, Taib, Ziad, Vikman, Kerstin

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X-ray Structure of Sensory Rhodopsin II at 2.1-Å Resolution von Royant, Antoine, Nollert, Peter, Edman, Karl, Neutze, Richard, Landau, Ehud M., Pebay-Peyroula, Eva, Navarro, Javier

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Bacteriorhodopsin: a high-resolution structural view of vectorial proton transport von Neutze, Richard, Pebay-Peyroula, Eva, Edman, Karl, Royant, Antoine, Navarro, Javier, Landau, Ehud M.

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Helix deformation is coupled to vectorial proton transport in the photocycle of bacteriorhodopsin von Royant, Antoine, Edman, Karl, Ursby, Thomas, Pebay-Peyroula, Eva, Landau, Ehud M., Neutze, Richard

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High-resolution X-ray structure of an early intermediate in the bacteriorhodopsin photocycle von Edman, Karl, Nollert, Peter, Royant, Antoine, Belrhali, Hassan, Pebay-Peyroula, Eva, Hajdu, Janos, Neutze, Richard, Landau, Ehud M.

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Deformation of Helix C in the Low Temperature L-intermediate of Bacteriorhodopsin von Edman, Karl, Royant, Antoine, Larsson, Gisela, Jacobson, Frida, Taylor, Tom, van der Spoel, David, Landau, Ehud M., Pebay-Peyroula, Eva, Neutze, Richard

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Unravelling Allosteric Cross-Talk between Co-Activator Peptide and Ligand Binding Site in Glucocorticoid Receptor von La Sala, Giuseppina, Gunnarsson, Anders, Edman, Karl, Tyrchan, Christian, Hogner, Anders, Frolov, Andrey

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Structural insight into allosteric modulation of protease-activated receptor 2 von Cheng, Robert K. Y., Fiez-Vandal, Cédric, Schlenker, Oliver, Edman, Karl, Aggeler, Birte, Brown, Dean G., Brown, Giles A., Cooke, Robert M., Dumelin, Christoph E., Doré, Andrew S., Geschwindner, Stefan, Grebner, Christoph, Hermansson, Nils-Olov, Jazayeri, Ali, Johansson, Patrik, Leong, Louis, Prihandoko, Rudi, Rappas, Mathieu, Soutter, Holly, Snijder, Arjan, Sundström, Linda, Tehan, Benjamin, Thornton, Peter, Troast, Dawn, Wiggin, Giselle, Zhukov, Andrei, Marshall, Fiona H., Dekker, Niek

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Unraveling the Allosteric Cross-Talk between the Coactivator Peptide and the Ligand-Binding Site in the Glucocorticoid Receptor von La Sala, Giuseppina, Gunnarsson, Anders, Edman, Karl, Tyrchan, Christian, Hogner, Anders, Frolov, Andrey I

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Binding Mode and Induced Fit Predictions for Prospective Computational Drug Design von Grebner, Christoph, Iegre, Jessica, Ulander, Johan, Edman, Karl, Hogner, Anders, Tyrchan, Christian

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Exploring Binding Mechanisms in Nuclear Hormone Receptors by Monte Carlo and X-ray-derived Motions von Grebner, Christoph, Lecina, Daniel, Gil, Victor, Ulander, Johan, Hansson, Pia, Dellsen, Anita, Tyrchan, Christian, Edman, Karl, Hogner, Anders, Guallar, Victor

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Quaternary glucocorticoid receptor structure highlights allosteric interdomain communication von Postel, Sandra, Wissler, Lisa, Johansson, Carina A., Gunnarsson, Anders, Gordon, Euan, Collins, Barry, Castaldo, Marie, Köhler, Christian, Öling, David, Johansson, Patrik, Fröderberg Roth, Linda, Beinsteiner, Brice, Dainty, Ian, Delaney, Stephen, Klaholz, Bruno P., Billas, Isabelle M. L., Edman, Karl

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Early Structural Rearrangements in the Photocycle of an Integral Membrane Sensory Receptor von Edman, Karl, Royant, Antoine, Nollert, Peter, Maxwell, Carrie A, Pebay-Peyroula, Eva, Navarro, Javier, Neutze, Richard, Landau, Ehud M

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Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile von Ripa, Lena, Edman, Karl, Dearman, Matthew, Edenro, Goran, Hendrickx, Ramon, Ullah, Victoria, Chang, Hui-Fang, Lepistö, Matti, Chapman, Dave, Geschwindner, Stefan, Wissler, Lisa, Svanberg, Petter, Lawitz, Karolina, Malmberg, Jesper, Nikitidis, Antonios, Olsson, Roine I, Bird, James, Llinas, Antoni, Hegelund-Myrbäck, Tove, Berger, Markus, Thorne, Philip, Harrison, Richard, Köhler, Christian, Drmota, Tomas

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Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction von Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin

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Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators von Munier, Claire C., De Maria, Leonardo, Edman, Karl, Gunnarsson, Anders, Longo, Marianna, MacKintosh, Carol, Patel, Saleha, Snijder, Arjan, Wissler, Lisa, Brunsveld, Luc, Ottmann, Christian, Perry, Matthew W.D.

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The effect of AZD9567 vs. prednisolone on glycaemic control in patients with type 2 diabetes mellitus: Results from a phase 2a clinical trial von Ambery, Philip, Zajac, Grzegorz, Almquist, Joachim, Prothon, Susanne, Astbury, Carol, Brown, Mary N., Nemes, Szilard, Nsabimana, Joselyne, Edman, Karl, Öberg, Lisa, Lepistö, Matti, Edenro, Goran, Dillmann, Inken, Mitra, Suman, Belfield, Graham, Keen, Christina, Heise, Tim

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Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction” von Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin

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