The small interferon-induced transmembrane genes and proteins von Siegrist, Fredy, Ebeling, Martin, Certa, Ulrich

Volltext

Discovery of Risdiplam, a Selective Survival of Motor Neuron‑2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA) von Ratni, Hasane, Ebeling, Martin, Baird, John, Bendels, Stefanie, Bylund, Johan, Chen, Karen S, Denk, Nora, Feng, Zhihua, Green, Luke, Guerard, Melanie, Jablonski, Philippe, Jacobsen, Bjoern, Khwaja, Omar, Kletzl, Heidemarie, Ko, Chien-Ping, Kustermann, Stefan, Marquet, Anne, Metzger, Friedrich, Mueller, Barbara, Naryshkin, Nikolai A, Paushkin, Sergey V, Pinard, Emmanuel, Poirier, Agnès, Reutlinger, Michael, Weetall, Marla, Zeller, Andreas, Zhao, Xin, Mueller, Lutz

Volltext

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers von Sivaramakrishnan, Manaswini, McCarthy, Kathleen D., Campagne, Sébastien, Huber, Sylwia, Meier, Sonja, Augustin, Angélique, Heckel, Tobias, Meistermann, Hélène, Hug, Melanie N., Birrer, Pascale, Moursy, Ahmed, Khawaja, Sarah, Schmucki, Roland, Berntenis, Nikos, Giroud, Nicolas, Golling, Sabrina, Tzouros, Manuel, Banfai, Balazs, Duran-Pacheco, Gonzalo, Lamerz, Jens, Hsiu Liu, Ying, Luebbers, Thomas, Ratni, Hasane, Ebeling, Martin, Cléry, Antoine, Paushkin, Sergey, Krainer, Adrian R., Allain, Frédéric H.-T., Metzger, Friedrich

Volltext

White-to-brown metabolic conversion of human adipocytes by JAK inhibition von Moisan, Annie, Lee, Youn-Kyoung, Zhang, Jitao David, Hudak, Carolyn S., Meyer, Claas A., Prummer, Michael, Zoffmann, Sannah, Truong, Hoa Hue, Ebeling, Martin, Kiialainen, Anna, Gérard, Régine, Xia, Fang, Schinzel, Robert T., Amrein, Kurt E., Cowan, Chad A.

Volltext

The Immunogenicity of Antibody Aggregates in a Novel Transgenic Mouse Model von Bessa, Juliana, Boeckle, Sabine, Beck, Hermann, Buckel, Thomas, Schlicht, Sonja, Ebeling, Martin, Kiialainen, Anna, Koulov, Atanas, Boll, Björn, Weiser, Thomas, Singer, Thomas, Rolink, Antonius G., Iglesias, Antonio

Volltext

Expression profiling of human immune cell subsets identifies miRNA-mRNA regulatory relationships correlated with cell type specific expression von Allantaz, Florence, Cheng, Donavan T, Bergauer, Tobias, Ravindran, Palanikumar, Rossier, Michel F, Ebeling, Martin, Badi, Laura, Reis, Bernhard, Bitter, Hans, D'Asaro, Matilde, Chiappe, Alberto, Sridhar, Sriram, Pacheco, Gonzalo Duran, Burczynski, Michael E, Hochstrasser, Denis, Vonderscher, Jacky, Matthes, Thomas

Volltext

AAM: a dataset of Artificial Audio Multitracks for diverse music information retrieval tasks von Ostermann, Fabian, Vatolkin, Igor, Ebeling, Martin

Volltext

CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity von Aires, Vanessa, Coulon-Bainier, Claire, Pavlovic, Anto, Ebeling, Martin, Schmucki, Roland, Schweitzer, Christophe, Kueng, Erich, Gutbier, Simon, Harde, Eva

Volltext

Detect tissue heterogeneity in gene expression data with BioQC von Zhang, Jitao David, Hatje, Klas, Sturm, Gregor, Broger, Clemens, Ebeling, Martin, Burtin, Martine, Terzi, Fabiola, Pomposiello, Silvia Ines, Badi, Laura

Volltext

Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways von Langlois, Julie, Lange, Simona, Ebeling, Martin, Macnair, Will, Schmucki, Roland, Li, Cenxiao, DeGeer, Jonathan, Sudharshan, Tania J J, Yong, V Wee, Shen, Yun-An, Harp, Christopher, Collin, Ludovic, Keaney, James

Volltext

Brain Shuttle Antibody for Alzheimer’s Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode von Weber, Felix, Bohrmann, Bernd, Niewoehner, Jens, Fischer, Jens A.A., Rueger, Petra, Tiefenthaler, Georg, Moelleken, Joerg, Bujotzek, Alexander, Brady, Kevin, Singer, Thomas, Ebeling, Martin, Iglesias, Antonio, Freskgård, Per-Ola

Volltext

Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes von Hellbach, Nicole, Peterson, Suzanne, Haehnke, Daniel, Shankar, Aditi, LaBarge, Samuel, Pivaroff, Cullen, Saenger, Stefanie, Thomas, Carolin, McCarthy, Kathleen, Ebeling, Martin, Hayhurst Bennett, Monica, Schmidt, Uli, Metzger, Friedrich

Volltext

mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis von Costa, Veronica, Aigner, Stefan, Vukcevic, Mirko, Sauter, Evelyn, Behr, Katharina, Ebeling, Martin, Dunkley, Tom, Friedlein, Arno, Zoffmann, Sannah, Meyer, Claas A., Knoflach, Frédéric, Lugert, Sebastian, Patsch, Christoph, Fjeldskaar, Fatiha, Chicha-Gaudimier, Laurie, Kiialainen, Anna, Piraino, Paolo, Bedoucha, Marc, Graf, Martin, Jessberger, Sebastian, Ghosh, Anirvan, Bischofberger, Josef, Jagasia, Ravi

Volltext

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct von Gehrlein, Alexandra, Udayar, Vinod, Anastasi, Nadia, Morella, Martino L., Ruf, Iris, Brugger, Doris, von der Mark, Sophia, Thoma, Ralf, Rufer, Arne, Heer, Dominik, Pfahler, Nina, Jochner, Anton, Niewoehner, Jens, Wolf, Luise, Fueth, Matthias, Ebeling, Martin, Villaseñor, Roberto, Zhu, Yanping, Deen, Matthew C., Shan, Xiaoyang, Ehsaei, Zahra, Taylor, Verdon, Sidransky, Ellen, Vocadlo, David J., Freskgård, Per-Ola, Jagasia, Ravi

Volltext

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes von Garcia-Lopez, Amparo, Tessaro, Francesca, Jonker, Hendrik R. A., Wacker, Anna, Richter, Christian, Comte, Arnaud, Berntenis, Nikolaos, Schmucki, Roland, Hatje, Klas, Petermann, Olivier, Chiriano, Gianpaolo, Perozzo, Remo, Sciarra, Daniel, Konieczny, Piotr, Faustino, Ignacio, Fournet, Guy, Orozco, Modesto, Artero, Ruben, Metzger, Friedrich, Ebeling, Martin, Goekjian, Peter, Joseph, Benoît, Schwalbe, Harald, Scapozza, Leonardo

Volltext

A Sensitive In Vitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides von Dieckmann, Andreas, Hagedorn, Peter H., Burki, Yvonne, Brügmann, Christine, Berrera, Marco, Ebeling, Martin, Singer, Thomas, Schuler, Franz

Volltext

Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia von Reich, Marvin, Paris, Iñaki, Ebeling, Martin, Dahm, Nadine, Schweitzer, Christophe, Reinhardt, Dieter, Schmucki, Roland, Prasad, Megana, Köchl, Fabian, Leist, Marcel, Cowley, Sally A, Zhang, Jitao David, Patsch, Christoph, Gutbier, Simon, Britschgi, Markus

Volltext

Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment von Ebeling, Martin, Küng, Erich, See, Angela, Broger, Clemens, Steiner, Guido, Berrera, Marco, Heckel, Tobias, Iniguez, Leonardo, Albert, Thomas, Schmucki, Roland, Biller, Hermann, Singer, Thomas, Certa, Ulrich

Volltext

Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats von Janz, Philipp, Knoflach, Frederic, Bleicher, Konrad, Belli, Sara, Biemans, Barbara, Schnider, Patrick, Ebeling, Martin, Grundschober, Christophe, Benekareddy, Madhurima

Volltext

Epithelial cells as active player in fibrosis: findings from an in vitro model von Moll, Solange, Ebeling, Martin, Weibel, Franziska, Farina, Annarita, Araujo Del Rosario, Andrea, Hoflack, Jean Christophe, Pomposiello, Silvia, Prunotto, Marco

Volltext