Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing von Lim, Chae Ho, Sun, Qi, Ratti, Karan, Lee, Soung-Hoon, Zheng, Ying, Takeo, Makoto, Lee, Wendy, Rabbani, Piul, Plikus, Maksim V., Cain, Jason E., Wang, David H., Watkins, D. Neil, Millar, Sarah, Taketo, M. Mark, Myung, Peggy, Cotsarelis, George, Ito, Mayumi

Volltext

MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat von Chen, Jasmine, Guanizo, Aleks C, Jakasekara, W Samantha N, Inampudi, Chaitanya, Luong, Quinton, Garama, Daniel J, Alamgeer, Muhammad, Thakur, Nishant, DeVeer, Michael, Ganju, Vinod, Watkins, D Neil, Cain, Jason E, Gough, Daniel J

Volltext

Distinctive molecular features of regenerative stem cells in the damaged male germline von La, Hue M., Liao, Jinyue, Legrand, Julien M. D., Rossello, Fernando J., Chan, Ai-Leen, Vaghjiani, Vijesh, Cain, Jason E., Papa, Antonella, Lee, Tin Lap, Hobbs, Robin M.

Volltext

ADAM17 selectively activates the IL‐6 trans‐signaling/ERK MAPK axis in KRAS‐addicted lung cancer von Saad, Mohamed I, Alhayyani, Sultan, McLeod, Louise, Yu, Liang, Alanazi, Mohammad, Deswaerte, Virginie, Tang, Ke, Jarde, Thierry, Smith, Julian A, Prodanovic, Zdenka, Tate, Michelle D, Balic, Jesse J, Watkins, D Neil, Cain, Jason E, Bozinovski, Steven, Algar, Elizabeth, Kohmoto, Tomohiro, Ebi, Hiromichi, Ferlin, Walter, Garbers, Christoph, Ruwanpura, Saleela, Sagi, Irit, Rose‐John, Stefan, Jenkins, Brendan J

Volltext

Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo von Akladios, Bassem, Mendoza Reinoso, Veronica, Cain, Jason E, Wang, Taopeng, Lambie, Duncan L, Watkins, D Neil, Beverdam, Annemiek

Volltext

Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling von Cochrane, Catherine R, Vaghjiani, Vijesh, Szczepny, Anette, Jayasekara, W Samantha N, Gonzalez-Rajal, Alvaro, Kikuchi, Kazu, McCaughan, Geoffrey W, Burgess, Andrew, Gough, Daniel J, Watkins, D Neil, Cain, Jason E

Volltext

Low-Dose Histone Deacetylase Inhibitor Treatment Leads to Tumor Growth Arrest and Multi-Lineage Differentiation of Malignant Rhabdoid Tumors von Muscat, Andrea, Popovski, Dean, Jayasekara, W Samantha N, Rossello, Fernando J, Ferguson, Melissa, Marini, Kieren D, Alamgeer, Muhammad, Algar, Elizabeth M, Downie, Peter, Watkins, D Neil, Cain, Jason E, Ashley, David M

Volltext

A non-genetic, cell cycle dependent mechanism of platinum resistance in lung adenocarcinoma von Gonzalez Rajal, Alvaro, Marzec, Kamila A, McCloy, Rachael A, Nobis, Max, Chin, Venessa, Hastings, Jordan F, Lai, Kaitao, Kennerson, Marina, Hughes, William E, Vaghjiani, Vijesh, Timpson, Paul, Cain, Jason E, Watkins, D Neil, Croucher, David R, Burgess, Andrew

Volltext

The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma von Sun, Xin, Vaghjiani, Vijesh, Jayasekara, W Samantha N, Cain, Jason E, St John, Justin C

Volltext

Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses von Pépin, Geneviève, Nejad, Charlotte, Ferrand, Jonathan, Thomas, Belinda J, Stunden, H James, Sanij, Elaine, Foo, Chwan-Hong, Stewart, Cameron R, Cain, Jason E, Bardin, Philip G, Williams, Bryan R G, Gantier, Michael P

Volltext

Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens von Leong, Tracy L, Marini, Kieren D, Rossello, Fernando J, Jayasekara, Samantha N, Russell, Prudence A, Prodanovic, Zdenka, Kumar, Beena, Ganju, Vinod, Alamgeer, Muhammad, Irving, Louis B, Steinfort, Daniel P, Peacock, Craig D, Cain, Jason E, Szczepny, Anette, Watkins, D Neil

Volltext

A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma von White, Christine L, Jayasekara, W Samantha N, Picard, Daniel, Chen, Jasmine, Watkins, D Neil, Cain, Jason E, Remke, Marc, Gough, Daniel J

Volltext

p53 and RB1 regulate Hedgehog responsiveness via autophagy-mediated ciliogenesis von Cain, Jason E., Watkins, D. Neil

Volltext

GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells von Cain, Jason E, Islam, Epshita, Haxho, Fiona, Chen, Lin, Bridgewater, Darren, Nieuwenhuis, Erica, Hui, Chi-Chung, Rosenblum, Norman D

Volltext

Hedgehog Signaling in the Maintenance of Cancer Stem Cells von Cochrane, Catherine R, Szczepny, Anette, Watkins, D Neil, Cain, Jason E

Volltext

Renal epithelial cells retain primary cilia during human acute renal allograft rejection injury von Verghese, Elizabeth, Martelotto, Luciano G, Cain, Jason E, Williams, Timothy M, Wise, Andrea F, Hill, Prudence A, Langham, Robyn G, Watkins, D Neil, Ricardo, Sharon D, Deane, James A

Volltext

Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies von Findlay, Izac J., De Iuliis, Geoffry N., Duchatel, Ryan J., Jackson, Evangeline R., Vitanza, Nicholas A., Cain, Jason E., Waszak, Sebastian M., Dun, Matthew D.

Volltext

Lessons learned from the developmental origins of childhood renal cancer von Chong, Wai Chin, Cain, Jason E.

Volltext

Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas von Przystal, Justyna M, Cianciolo Cosentino, Chiara, Yadavilli, Sridevi, Zhang, Jie, Laternser, Sandra, Bonner, Erin R, Prasad, Rachna, Dawood, Adam A, Lobeto, Nina, Chin Chong, Wai, Biery, Matt C, Myers, Carrie, Olson, James M, Panditharatna, Eshini, Kritzer, Bettina, Mourabit, Sulayman, Vitanza, Nicholas A, Filbin, Mariella G, de Iuliis, Geoffry N, Dun, Matthew D, Koschmann, Carl, Cain, Jason E, Grotzer, Michael A, Waszak, Sebastian M, Mueller, Sabine, Nazarian, Javad

Volltext

Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor von Blake, Joshua, Hu, Di, Cain, Jason E, Rosenblum, Norman D

Volltext