Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia von Ma, Jun, Zhao, Shoujing, Qiao, Xinan, Knight, Tristan, Edwards, Holly, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H, White, Kathryn, Wang, Guan, Zhao, Lijing, Lin, Hai, Wang, Yue, Taub, Jeffrey W, Ge, Yubin

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The vulnerable primed cancer stem cells in disguise: demystifying the role of Maspin von Sheng, Shijie, Bernardo, Margarida, Dzinic, Sijana H., Chen, Kang, Sakr, Wael A.

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Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia von Li, Xinyu, Su, Yongwei, Madlambayan, Gerard, Edwards, Holly, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H, White, Kathryn, Ma, Jun, Knight, Tristan, Wang, Guan, Wang, Yue, Yang, Jay, Taub, Jeffrey W, Lin, Hai, Ge, Yubin

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The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia von Li, Xinyu, Su, Yongwei, Hege, Katie, Madlambayan, Gerard, Edwards, Holly, Knight, Tristan, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Yang, Jay, Miller, Regan, Wang, Guan, Zhao, Lijing, Wang, Yue, Lin, Hai, Taub, Jeffrey W., Ge, Yubin

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Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment von Wallace-Povirk, Adrianne, Rubinsak, Lisa, Malysa, Agnes, Dzinic, Sijana H., Ravindra, Manasa, Schneider, Mathew, Glassbrook, James, O’Connor, Carrie, Hou, Zhanjun, Kim, Seongho, Back, Jessica, Polin, Lisa, Morris, Robert T., Gangjee, Aleem, Gibson, Heather, Matherly, Larry H.

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Identification of an intrinsic determinant critical for maspin subcellular localization and function von Dzinic, Sijana H, Kaplun, Alexander, Li, Xiaohua, Bernardo, Margarida, Meng, Yonghong, Dean, Ivory, Krass, David, Stemmer, Paul, Shin, Namhee, Lonardo, Fulvio, Sheng, Shijie

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Maspin differential expression patterns as a potential marker for targeted screening of esophageal adenocarcinoma/gastroesophageal junction adenocarcinoma von Dzinic, Sijana H, Mahdi, Zaid, Bernardo, M Margarida, Vranic, Semir, Beydoun, Haya, Nahra, Nadine, Alijagic, Amra, Harajli, Deanna, Pang, Aaron, Saliganan, Dan M, Rahman, Abid M, Skenderi, Faruk, Hasanbegovic, Berisa, Dyson, Gregory, Beydoun, Rafic, Sheng, Shijie

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The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML von Qiao, Xinan, Ma, Jun, Knight, Tristan, Su, Yongwei, Edwards, Holly, Polin, Lisa, Li, Jing, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Wang, Jian, Lin, Hai, Wang, Yue, Wang, Liping, Wang, Guan, Taub, Jeffrey W., Ge, Yubin

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Novel Pyrrolo[3,2- d ]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy von Dekhne, Aamod S, Shah, Khushbu, Ducker, Gregory S, Katinas, Jade M, Wong-Roushar, Jennifer, Nayeen, Md Junayed, Doshi, Arpit, Ning, Changwen, Bao, Xun, Frühauf, Josephine, Liu, Jenney, Wallace-Povirk, Adrianne, O'Connor, Carrie, Dzinic, Sijana H, White, Kathryn, Kushner, Juiwanna, Kim, Seongho, Hüttemann, Maik, Polin, Lisa, Rabinowitz, Joshua D, Li, Jing, Hou, Zhanjun, Dann, 3rd, Charles E, Gangjee, Aleem, Matherly, Larry H

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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro von Hurrish, Katie H, Su, Yongwei, Patel, Shraddha, Ramage, Cassandra L, Zhao, Jianlei, Temby, Brianna R, Carter, Jenna L, Edwards, Holly, Buck, Steven A, Wiley, Sandra E, Hüttemann, Maik, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H, White, Kathryn, Bao, Xun, Li, Jing, Yang, Jay, Boerner, Julie, Hou, Zhanjun, Al-Atrash, Gheath, Konoplev, Sergej N, Busquets, Jonathan, Tiziani, Stefano, Matherly, Larry H, Taub, Jeffrey W, Konopleva, Marina, Ge, Yubin, Baran, Natalia

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Tackling tumor heterogeneity and phenotypic plasticity in cancer precision medicine: our experience and a literature review von Sheng, Shijie, Margarida Bernardo, M., Dzinic, Sijana H., Chen, Kang, Heath, Elisabeth I., Sakr, Wael A.

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The Opportunity of Precision Medicine for Breast Cancer With Context‐Sensitive Tumor Suppressor Maspin von Bernardo, Margarida M., Dzinic, Sijana H., Matta, Maria J., Dean, Ivory, Saker, Lina, Sheng, Shijie

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Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation von Liu, Fangbing, Kalpage, Hasini A., Wang, Deying, Edwards, Holly, Huettemann, Maik, Ma, Jun, Su, Yongwei, Carter, Jenna, Li, Xinyu, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Wang, Guan, Taub, Jeffrey W., Ge, Yubin

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Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy von Dekhne, Aamod S, Shah, Khushbu, Ducker, Gregory S, Katinas, Jade M, Wong-Roushar, Jennifer, Nayeen, Md Junayed, Doshi, Arpit, Ning, Changwen, Bao, Xun, Frühauf, Josephine, Liu, Jenney, Wallace-Povirk, Adrianne, O'Connor, Carrie, Dzinic, Sijana H, White, Kathryn, Kushner, Juiwanna, Kim, Seongho, Hüttemann, Maik, Polin, Lisa, Rabinowitz, Joshua D, Li, Jing, Hou, Zhanjun, Dann, Charles E, Gangjee, Aleem, Matherly, Larry H

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Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia von Luedtke, Daniel A., Su, Yongwei, Ma, Jun, Li, Xinyu, Buck, Steven A., Edwards, Holly, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Lin, Hai, Taub, Jeffrey W., Ge, Yubin

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The secretion and biological function of tumor suppressor maspin as an exosome cargo protein von Dean, Ivory, Dzinic, Sijana H, Bernardo, M Margarida, Zou, Yi, Kimler, Vickie, Li, Xiaohua, Kaplun, Alexander, Granneman, James, Mao, Guangzhao, Sheng, Shijie

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A phase II trial of ganetespib, a heat shock protein 90 Hsp90) inhibitor, in patients with docetaxel-pretreated metastatic castrate-resistant prostate cancer (CRPC)-a prostate canc... von Thakur, Manish K., Heilbrun, Lance K., Sheng, Shijie, Stein, Mark, Liu, Glenn, Antonarakis, Emmanuel S., Vaishampayan, Ulka, Dzinic, Sijana H., Li, Xiaohua, Freeman, Stacy, Smith, Daryn, Heath, Elisabeth I.

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Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity von Bernardo, M Margarida, Kaplun, Alexander, Dzinic, Sijana H, Li, Xiaohua, Irish, Jonathan, Mujagic, Adelina, Jakupovic, Benjamin, Back, Jessica B, Van Buren, Eric, Han, Xiang, Dean, Ivory, Chen, Yong Q, Heath, Elisabeth, Sakr, Wael, Sheng, Shijie

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An Essential Role of Maspin in Embryogenesis and Tumor Suppression von Dzinic, Sijana H, Bernardo, M Margarida, Li, Xiaohua, Fernandez-Valdivia, Rodrigo, Ho, Ye-Shih, Mi, Qing-Sheng, Bandyopadhyay, Sudeshna, Lonardo, Fulvio, Vranic, Semir, Oliveira, Daniel S M, Bonfil, R Daniel, Dyson, Gregory, Chen, Kang, Omerovic, Almasa, Sheng, Xiujie, Han, Xiang, Wu, Dinghong, Bi, Xinling, Cabaravdic, Dzenana, Jakupovic, Una, Wahba, Marian, Pang, Aaron, Harajli, Deanna, Sakr, Wael A, Sheng, Shijie

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Maspin expression in prostate tumor elicits host anti-tumor immunity von Dzinic, Sijana H, Chen, Kang, Thakur, Archana, Kaplun, Alexander, Bonfil, R Daniel, Li, Xiaohua, Liu, Jason, Bernardo, M Margarida, Saliganan, Allen, Back, Jessica B, Yano, Hiroshi, Schalk, Dana L, Tomaszewski, Elyse N, Beydoun, Ahmed S, Dyson, Gregory, Mujagic, Adelina, Krass, David, Dean, Ivory, Mi, Qing-Sheng, Heath, Elisabeth, Sakr, Wael, Lum, Lawrence G, Sheng, Shijie

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