Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges von Day, Chi-Ping, Merlino, Glenn, Van Dyke, Terry

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Pten dose dictates cancer progression in the prostate von Trotman, Lloyd C, Niki, Masaru, Dotan, Zohar A, Koutcher, Jason A, Di Cristofano, Antonio, Xiao, Andrew, Khoo, Alan S, Roy-Burman, Pradip, Greenberg, Norman M, Van Dyke, Terry, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo

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Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer von Szabova, Ludmila, Bupp, Sujata, Kamal, Muhaymin, Householder, Deborah B, Hernandez, Lidia, Schlomer, Jerome J, Baran, Maureen L, Yi, Ming, Stephens, Robert M, Annunziata, Christina M, Martin, Philip L, Van Dyke, Terry A, Weaver Ohler, Zoe, Difilippantonio, Simone

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Evolutionary etiology of high-grade astrocytomas von Song, Yurong, Zhang, Qian, Kutlu, Burak, Difilippantonio, Simone, Bash, Ryan, Gilbert, Debra, Yin, Chaoying, O'Sullivan, T. Norene, Yang, Chunyu, Kozlov, Serguei, Bullitt, Elizabeth, McCarthy, Ken D., Kafri, Tal, Louis, David N., Miller, C. Ryan, Hood, Leroy, Van Dyke, Terry

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RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice von Song, Yurong, Sullivan, Teresa, Klarmann, Kimberly, Gilbert, Debra, O'Sullivan, T Norene, Lu, Lucy, Wang, Sophie, Haines, Diana C, Van Dyke, Terry, Keller, Jonathan R

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Adeno-associated virus vectors: potential applications for cancer gene therapy von Li, Chengwen, Bowles, Dawn E, van Dyke, Terry, Samulski, Richard Jude

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Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy von Sherman, Mara H., Yu, Ruth T., Engle, Dannielle D., Ding, Ning, Atkins, Annette R., Tiriac, Herve, Collisson, Eric A., Connor, Frances, Van Dyke, Terry, Kozlov, Serguei, Martin, Philip, Tseng, Tiffany W., Dawson, David W., Donahue, Timothy R., Masamune, Atsushi, Shimosegawa, Tooru, Apte, Minoti V., Wilson, Jeremy S., Ng, Beverly, Lau, Sue Lynn, Gunton, Jenny E., Wahl, Geoffrey M., Hunter, Tony, Drebin, Jeffrey A., O’Dwyer, Peter J., Liddle, Christopher, Tuveson, David A., Downes, Michael, Evans, Ronald M.

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Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC von Walter, Annette O, Sjin, Robert Tjin Tham, Haringsma, Henry J, Ohashi, Kadoaki, Sun, Jing, Lee, Kwangho, Dubrovskiy, Aleksandr, Labenski, Matthew, Zhu, Zhendong, Wang, Zhigang, Sheets, Michael, St Martin, Thia, Karp, Russell, van Kalken, Dan, Chaturvedi, Prasoon, Niu, Deqiang, Nacht, Mariana, Petter, Russell C, Westlin, William, Lin, Kevin, Jaw-Tsai, Sarah, Raponi, Mitch, Van Dyke, Terry, Etter, Jeff, Weaver, Zoe, Pao, William, Singh, Juswinder, Simmons, Andrew D, Harding, Thomas C, Allen, Andrew

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Expression Quantitative Trait Loci and Receptor Pharmacology Implicate Arg1 and the GABA-A Receptor as Therapeutic Targets in Neuroblastoma von Hackett, Christopher S., Quigley, David A., Wong, Robyn A., Chen, Justin, Cheng, Christine, Song, Young K., Wei, Jun S., Pawlikowska, Ludmila, Bao, Yun, Goldenberg, David D., Nguyen, Kim, Gustafson, W. Clay, Rallapalli, Sundari K., Cho, Yoon-Jae, Cook, James M., Kozlov, Serguei, Mao, Jian-Hua, Van Dyke, Terry, Kwok, Pui-Yan, Khan, Javed, Balmain, Allan, Fan, QiWen, Weiss, William A.

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Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy von Pérez-Guijarro, Eva, Yang, Howard H., Araya, Romina E., El Meskini, Rajaa, Michael, Helen T., Vodnala, Suman Kumar, Marie, Kerrie L., Smith, Cari, Chin, Sung, Lam, Khiem C., Thorkelsson, Andres, Iacovelli, Anthony J., Kulaga, Alan, Fon, Anyen, Michalowski, Aleksandra M., Hugo, Willy, Lo, Roger S., Restifo, Nicholas P., Sharan, Shyam K., Van Dyke, Terry, Goldszmid, Romina S., Weaver Ohler, Zoe, Lee, Maxwell P., Day, Chi-Ping, Merlino, Glenn

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The genetics of splicing in neuroblastoma von Chen, Justin, Hackett, Christopher S, Zhang, Shile, Song, Young K, Bell, Robert J A, Molinaro, Annette M, Quigley, David A, Balmain, Allan, Song, Jun S, Costello, Joseph F, Gustafson, W Clay, Van Dyke, Terry, Kwok, Pui-Yan, Khan, Javed, Weiss, William A

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Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues von Johnson, Carrie E, Huang, Yolanda Y, Parrish, Amanda B, Smith, Michelle I, Vaughn, Allyson E, Zhang, Qian, Wright, Kevin M, Van Dyke, Terry, Wechsler-Reya, Robert J, Kornbluth, Sally, Deshmukh, Mohanish

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Inactivation of TRP53, PTEN, RB1, and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis von Shi, Mingxin, Whorton, Allison E, Sekulovski, Nikola, Paquet, Marilène, MacLean, James A, Song, Yurong, Van Dyke, Terry, Hayashi, Kanako

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Characterization of an Mtbp Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model von Ranjan, Atul, Thoenen, Elizabeth A., Kaida, Atsushi, Wood, Stephanie, Van Dyke, Terry, Iwakuma, Tomoo

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pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia von Simin, Karl, Wu, Hua, Lu, Lucy, Pinkel, Dan, Albertson, Donna, Cardiff, Robert D, Van Dyke, Terry

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Genetically Engineered Mouse Models in Cancer Research von Walrath, Jessica C., Hawes, Jessica J., Van Dyke, Terry, Reilly, Karlyne M.

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Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer von SZABOVA, Ludmila, CHAOYING YIN, MCDUNN, Jonathan E, MARTIN, Philip L, VAN DYKE, Terry, DIFILIPPANTONIO, Simone, BUPP, Sujata, GUERIN, Theresa M, SCHLOMER, Jerome J, HOUSEHOLDER, Deborah B, BARAN, Maureen L, MING YI, YURONG SONG, WENPING SUN

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Distinct Biomarker Profiles and TCR Sequence Diversity Characterize the Response to PD-L1 Blockade in a Mouse Melanoma Model von El Meskini, Rajaa, Atkinson, Devon, Kulaga, Alan, Abdelmaksoud, Abdalla, Gumprecht, Michelle, Pate, Nathan, Hayes, Susana, Oberst, Michael, Kaplan, Ian M., Raber, Patrick, Van Dyke, Terry, Sharan, Shyam K., Hollingsworth, Robert, Day, Chi-Ping, Merlino, Glenn, Ohler, Zoe Weaver

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Sense out of missense von Dyke, Terry Van

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Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles von Li, Wuping, Asokan, Aravind, Wu, Zhijian, Van Dyke, Terry, DiPrimio, Nina, Johnson, Jarrod S, Govindaswamy, Lakshmanan, Agbandje-McKenna, Mavis, Leichtle, Stefan, Eugene Redmond Jr, D, McCown, Thomas J, Petermann, Kimberly B, Sharpless, Norman E, Samulski, Richard J

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