The genomic landscape of cutaneous melanoma von Zhang, Tongwu, Dutton-Regester, Ken, Brown, Kevin M., Hayward, Nicholas K.

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Co‐targeting bromodomain and extra‐terminal proteins and MCL1 induces synergistic cell death in melanoma von Tseng, Hsin‐Yi, Dreyer, Jan, Emran, Abdullah Al, Gunatilake, Dilini, Pirozyan, Mehdi, Cullinane, Carleen, Dutton‐Regester, Ken, Rizos, Helen, Hayward, Nicholas K., McArthur, Grant, Hersey, Peter, Tiffen, Jessamy, Gallagher, Stuart

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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq von Tirosh, Itay, Izar, Benjamin, Prakadan, Sanjay M., Wadsworth, Marc H., Treacy, Daniel, Trombetta, John J., Rotem, Asaf, Rodman, Christopher, Lian, Christine, Murphy, George, Fallahi-Sichani, Mohammad, Dutton-Regester, Ken, Lin, Jia-Ren, Cohen, Ofir, Shah, Parin, Lu, Diana, Genshaft, Alex S., Hughes, Travis K., Ziegler, Carly G. K., Kazer, Samuel W., Gaillard, Aleth, Kolb, Kellie E., Villani, Alexandra-Chloé, Johannessen, Cory M., Andreev, Aleksandr Y., Van Allen, Eliezer M., Bertagnolli, Monica, Sorger, Peter K., Sullivan, Ryan J., Flaherty, Keith T., Frederick, Dennie T., Jané-Valbuena, Judit, Yoon, Charles H., Rozenblatt-Rosen, Orit, Shalek, Alex K., Regev, Aviv, Garraway, Levi A.

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Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor von Boyle, Glen M., Woods, Susan L., Bonazzi, Vanessa F., Stark, Mitchell S., Hacker, Elke, Aoude, Lauren G., Dutton-Regester, Ken, Cook, Anthony L., Sturm, Richard A., Hayward, Nicholas K.

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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes von Cao, Juxiang, Wan, Lixin, Hacker, Elke, Dai, Xiangpeng, Lenna, Stefania, Jimenez-Cervantes, Celia, Wang, Yongjun, Leslie, Nick R., Xu, George X., Widlund, Hans R., Ryu, Byungwoo, Alani, Rhoda M., Dutton-Regester, Ken, Goding, Colin R., Hayward, Nicholas K., Wei, Wenyi, Cui, Rutao

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Recurrent inactivating RASA2 mutations in melanoma von Arafeh, Rand, Qutob, Nouar, Emmanuel, Rafi, Keren-Paz, Alona, Madore, Jason, Elkahloun, Abdel, Wilmott, James S, Gartner, Jared J, Di Pizio, Antonella, Winograd-Katz, Sabina, Sindiri, Sivasish, Rotkopf, Ron, Dutton-Regester, Ken, Johansson, Peter, Pritchard, Antonia L, Waddell, Nicola, Hill, Victoria K, Lin, Jimmy C, Hevroni, Yael, Rosenberg, Steven A, Khan, Javed, Ben-Dor, Shifra, Niv, Masha Y, Ulitsky, Igor, Mann, Graham J, Scolyer, Richard A, Hayward, Nicholas K, Samuels, Yardena

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Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes von Tiffen, Jessamy C, Gunatilake, Dilini, Gallagher, Stuart J, Gowrishankar, Kavitha, Heinemann, Anja, Cullinane, Carleen, Dutton-Regester, Ken, Pupo, Gulietta M, Strbenac, Dario, Yang, Jean Y, Madore, Jason, Mann, Graham J, Hayward, Nicholas K, McArthur, Grant A, Filipp, Fabian V, Hersey, Peter

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Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines von Young, Richard J., Waldeck, Kelly, Martin, Claire, Foo, Jung H., Cameron, Donald P., Kirby, Laura, Do, Hongdo, Mitchell, Catherine, Cullinane, Carleen, Liu, Wendy, Fox, Stephen B., Dutton-Regester, Ken, Hayward, Nicholas K., Jene, Nicholas, Dobrovic, Alexander, Pearson, Richard B., Christensen, James G., Randolph, Sophia, McArthur, Grant A., Sheppard, Karen E.

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Reviewing the somatic genetics of melanoma: from current to future analytical approaches von Dutton-Regester, Ken, Hayward, Nicholas K.

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A high-throughput panel for identifying clinically relevant mutation profiles in melanoma von Dutton-Regester, Ken, Irwin, Darryl, Hunt, Priscilla, Aoude, Lauren G, Tembe, Varsha, Pupo, Gulietta M, Lanagan, Cathy, Carter, Candace D, O'Connor, Linda, O'Rourke, Michael, Scolyer, Richard A, Mann, Graham J, Schmidt, Christopher W, Herington, Adrian, Hayward, Nicholas K

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Somatic Mutations in MAP3K5 Attenuate Its Proapoptotic Function in Melanoma through Increased Binding to Thioredoxin von Prickett, Todd D., Zerlanko, Brad, Gartner, Jared J., Parker, Stephen C.J., Dutton-Regester, Ken, Lin, Jimmy C., Teer, Jamie K., Wei, Xiaomu, Jiang, Jiji, NISC Comparative Sequencing Program, Chen, Guo, Davies, Michael A., Gershenwald, Jeffrey E., Robinson, William, Robinson, Steven, Hayward, Nicholas K., Rosenberg, Steven A., Margulies, Elliott H., Samuels, Yardena

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BRAF/NRAS wild-type melanoma, NF1 status and sensitivity to trametinib von Ranzani, Marco, Alifrangis, Constantine, Perna, Daniele, Dutton-Regester, Ken, Pritchard, Antonia, Wong, Kim, Rashid, Mamunur, Robles-Espinoza, Carla Daniela, Hayward, Nicholas K., McDermott, Ultan, Garnett, Mathew, Adams, David J.

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Science and Health von Dutton-Regester, Ken

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Melanomas of unknown primary have a mutation profile consistent with cutaneous sun-exposed melanoma von Dutton-Regester, Ken, Kakavand, Hojabr, Aoude, Lauren G., Stark, Mitchell S., Gartside, Michael G., Johansson, Peter, O'Connor, Linda, Lanagan, Cathy, Tembe, Varsha, Pupo, Gulietta M., Haydu, Lauren E., Schmidt, Christopher W., Mann, Graham J., Thompson, John F., Scolyer, Richard A., Hayward, Nicholas K.

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Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene von Dutton-Regester, Ken, Aoude, Lauren G., Nancarrow, Derek J., Stark, Mitchell S., O'Connor, Linda, Lanagan, Cathy, Pupo, Gulietta M., Tembe, Varsha, Carter, Candace D., O'Rourke, Michael, Scolyer, Richard A., Mann, Graham J., Schmidt, Christopher W., Herington, Adrian, Hayward, Nicholas K.

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Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma von Gartner, Jared J., Parker, Stephen C. J., Prickett, Todd D., Dutton-Regester, Ken, Stitzel, Michael L., Lin, Jimmy C., Davis, Sean, Simhadri, Vijaya L., Jha, Sujata, Katagiri, Nobuko, Gotea, Valer, Teer, Jamie K., Wei, Xiaomu, Morken, Mario A., Bhanot, Umesh K., Chen, Guo, Elnitski, Laura L., Davies, Michael A., Gershenwald, Jeffrey E., Carter, Hannah, Karchin, Rachel, Robinson, William, Robinson, Steven, Rosenberg, Steven A., Collins, Francis S., Parmigiani, Giovanni, Komar, Anton A., Kimchi-Sarfaty, Chava, Hayward, Nicholas K., Margulies, Elliott H., Samuels, Yardena

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Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing von Stark, Mitchell S, Woods, Susan L, Gartside, Michael G, Bonazzi, Vanessa F, Dutton-Regester, Ken, Aoude, Lauren G, Chow, Donald, Sereduk, Chris, Niemi, Natalie M, Tang, Nanyun, Ellis, Jonathan J, Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M, Pollak, Thomas, Youngkin, David, Brooks, Bradford R, Lanagan, Catherine, Schmidt, Christopher W, Kobe, Bostjan, MacKeigan, Jeffrey P, Yin, Hongwei, Brown, Kevin M, Gibbs, Richard, Trent, Jeffrey, Hayward, Nicholas K

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Abstract 4226: TNFRSF14 is a cell surface marker of MITF expression in melanoma von Dutton-Regester, Ken, Hayward, Nicholas K.

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Abstract 237: Enrichment of AXL-high/ MITF-low melanoma cells in the presence of MAPK inhibitors in vitro von Dutton-Regester, Ken, Garraway, Levi

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma von Krauthammer, Michael, Kong, Yong, Ha, Byung Hak, Evans, Perry, Bacchiocchi, Antonella, McCusker, Jamie P, Cheng, Elaine, Davis, Matthew J, Goh, Gerald, Choi, Murim, Ariyan, Stephan, Narayan, Deepak, Dutton-Regester, Ken, Capatana, Ana, Holman, Edna C, Bosenberg, Marcus, Sznol, Mario, Kluger, Harriet M, Brash, Douglas E, Stern, David F, Materin, Miguel A, Lo, Roger S, Mane, Shrikant, Ma, Shuangge, Kidd, Kenneth K, Hayward, Nicholas K, Lifton, Richard P, Schlessinger, Joseph, Boggon, Titus J, Halaban, Ruth

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