Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage von Pandya, Priyanka, Sayers, Robert O., Ting, Joey P., Morshedian, Shaghayegh, Torres, Carina, Cudal, Justine S., Zhang, Kai, Fitchett, Jonathan R., Zhang, Qing, Zhang, Feiyu F., Wang, Jing, Durbin, Jim D., Carrillo, Juan J., Espada, Alfonso, Broughton, Howard, Qian, Yuewei, Afshar, Sepideh

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Probing the Binding Mechanism of Acylated Peptides to Human Serum Albumin von Hu, Haitao, Ransdell, Anthony S., Qu, Hongchang, Durbin, Jim D., Valenzuela, Francisco A., Hernandez-Buquer, Selene, Gonciarz, Malgorzata D.

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N+1 Engineering of an Aspartate Isomerization Hotspot in the Complementarity-Determining Region of a Monoclonal Antibody von Patel, Chetan N., Bauer, Scott P., Davies, Julian, Durbin, Jim D., Shiyanova, Tatiyana L., Zhang, Kai, Tang, Jason X.

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Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody von Boyles, Jeffrey S, Beidler, Catherine B, Strifler, Beth A, Girard, Daniel S, Druzina, Zhanna, Durbin, Jim D, Swearingen, Michelle L, Lee, Linda N, Kikly, Kristine, Chintharlapalli, Sudhakar, Witcher, Derrick R

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Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt) von Lugar, Charles W, Clarke, Christian A, Morphy, Richard, Rudyk, Helene, Sapmaz, Selma, Stites, Ryan E, Vaught, Grant M, Furness, Kelly, Broughton, Howard B, Durst, Greg L, Clawson, David K, Stout, Stephanie L, Guo, Sherry Y, Durbin, Jim D, Stayrook, Keith R, Edmondson, Denise D, Kikly, Kristy, New, Nicole E, Bina, Holly A, Chambers, Mark G, Shetler, Pamela, Chang, William Y, Chang, Veavi Ching-Yun, Barr, Rob, Gough, Wendy H, Steele, Jimmy P, Getman, Brian, Patel, Nita, Mathes, Brian M, Richardson, Timothy I

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Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design von Jones, Spencer B, Pfeifer, Lance A, Bleisch, Thomas J, Beauchamp, Thomas J, Durbin, Jim D, Klimkowski, V. Joseph, Hughes, Norman E, Rito, Christopher J, Dao, Yen, Gruber, Joseph M, Bui, Hai, Chambers, Mark G, Chandrasekhar, Srinivasan, Lin, Chaohua, McCann, Denis J, Mudra, Daniel R, Oskins, Jennifer L, Swearingen, Craig A, Thirunavukkarasu, Kannan, Norman, Bryan H

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A Novel Glucokinase Activator Modulates Pancreatic Islet and Hepatocyte Function von Efanov, Alexander M, Barrett, David G, Brenner, Martin B, Briggs, Stephen L, Delaunois, Annie, Durbin, Jim D, Giese, Ulrich, Guo, Haihong, Radloff, Mark, Gil, Gema Sanz, Sewing, Sabine, Wang, Yong, Weichert, Andreas, Zaliani, Andrea, Gromada, Jesper

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Identification of Potent and Selective Hydantoin Inhibitors of Aggrecanase‑1 and Aggrecanase‑2 That Are Efficacious in Both Chemical and Surgical Models of Osteoarthritis von Durham, Timothy B, Klimkowski, Valentine J, Rito, Christopher J, Marimuthu, Jothirajah, Toth, James L, Liu, Chin, Durbin, Jim D, Stout, Stephanie L, Adams, Lisa, Swearingen, Craig, Lin, Chaohua, Chambers, Mark G, Thirunavukkarasu, Kannan, Wiley, Michael R

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Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm von Jadhav, Prabhakar K, Schiffler, Matthew A, Gavardinas, Kostas, Kim, Euibong J, Matthews, Donald P, Staszak, Michael A, Coffey, D. Scott, Shaw, Bruce W, Cassidy, Kenneth C, Brier, Richard A, Zhang, Yuke, Christie, Robert M, Matter, William F, Qing, Keyun, Durbin, Jim D, Wang, Yong, Deng, Gary G

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Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 5: Combined A- and C-ring structure–activity relationship studies von Richardson, Timothy I., Dodge, Jeffrey A., Wang, Yong, Durbin, Jim D., Krishnan, Venkatesh, Norman, Bryan H.

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Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 3: Synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification von Richardson, Timothy I., Dodge, Jeffrey A., Durst, Gregory L., Pfeifer, Lance A., Shah, Jikesh, Wang, Yong, Durbin, Jim D., Krishnan, Venkatesh, Norman, Bryan H.

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Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring von Norman, Bryan H., Richardson, Timothy I., Dodge, Jeffrey A., Pfeifer, Lance A., Durst, Gregory L., Wang, Yong, Durbin, Jim D., Krishnan, Venkatesh, Dinn, Sean R., Liu, Shengquan, Reilly, John E., Ryter, Kendal T.

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Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 2: Structure–activity relationship studies on the benzopyran scaffold von Richardson, Timothy I., Norman, Bryan H., Lugar, Charles W., Jones, Scott A., Wang, Yong, Durbin, Jim D., Krishnan, Venkatesh, Dodge, Jeffrey A.

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Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor von Durham, Timothy B., Hao, Junliang, Spinazze, Patrick, Stack, Douglas R., Toth, James L., Massey, Steven, Mbofana, Curren T., Johnston, Richard D., Lineswala, Jayana P., Wrobleski, Aaron, Mínguez, Jose Miguel, Perez, Carlos, Smith, Daryl L., Lamar, Jason, Leon, Rebecca, Corkins, Christopher, Durbin, Jim, Tung, Frances, Guo, Sherry, Linder, Ryan J., Yumibe, Nathan, Wang, Wei, MacKrell, James, Antonellis, Meghan, Mascaro, Bethany

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Abstract P142: Preclinical characterization of LOX-22783, a highly potent, mutant-selective and brain-penetrant allosteric PI3Kα H1047R inhibitor von Klippel, Anke, Wang, Rui, Puca, Loredana, Faber, Andrew Lee, Shen, Weihua, Bhagwat, Shripad V., Karukurichi, Kannan, Zhang, Feiyu Fred, Perez, Carmen, Rama, Ramon, Ramos, Ana, Zheng, Yi, Bonday, Zahid, Thomas, James, Brooks, Harold B., Kindler, Lisa J., Bogner, Sarah M., Zolfaghari, Parisa, II, Mark Hicks, Callies, Sophie, Mattioni, Brian, LeBrun, Laurie, Durbin, Jim, Anderson, Erin, Mayne, Chris, Kesicki, Edward, Kolakowski, Gabrielle, Andrews, Steven W., Brandhuber, Barbara J.

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Discovery and characterization of a neutralizing pan-ELR plus CXC chemokine monoclonal antibody von Boyles, Jeffrey S., Beidler, Catherine B., Strifler, Beth A., Girard, Daniel S., Druzina, Zhanna, Durbin, Jim D., Swearingen, Michelle L., Lee, Linda N., Kikly, Kristine, Chintharlapalli, Sudhakar, Witcher, Derrick R.

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Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody von Boyles, Jeffrey S., Beidler, Catherine B., Strifler, Beth A., Girard, Daniel S., Druzina, Zhanna, Durbin, Jim D., Swearingen, Michelle L., Lee, Linda N., Kikly, Kristine, Chintharlapalli, Sudhakar, Witcher, Derrick R.

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Some managers thrive on corporate speak because they think it's how executives communicate von Durbin, Jim

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Method for crystallizing human beta secretase in complex with an inhibitor von PRINCE D. BRYAN, BENSON TIMOTHY E, DURBIN JIM D

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Method for crystallizing human beta secretase in complex with an inhibitor von Benson, Timothy E, Durbin, Jim D, Prince, D. Bryan

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