A novel method for the 1,2-carbonyl transposition of pleuromutilins von Duquenne, Céline, Gallagher, Timothy F., Axten, Jeffrey M.

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Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2 von Verma, Sharad K, Tian, Xinrong, LaFrance, Louis V, Duquenne, Céline, Suarez, Dominic P, Newlander, Kenneth A, Romeril, Stuart P, Burgess, Joelle L, Grant, Seth W, Brackley, James A, Graves, Alan P, Scherzer, Daryl A, Shu, Art, Thompson, Christine, Ott, Heidi M, Aller, Glenn S. Van, Machutta, Carl A, Diaz, Elsie, Jiang, Yong, Johnson, Neil W, Knight, Steven D, Kruger, Ryan G, McCabe, Michael T, Dhanak, Dashyant, Tummino, Peter J, Creasy, Caretha L, Miller, William H

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Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activity von Axten, Jeffrey M., Medina, Jesús R., Blackledge, Charles W., Duquenne, Céline, Grant, Seth W., Bobko, Mark A., Peng, Tony, Miller, William H., Pinckney, Theresa, Gallagher, Timothy F., Kulkarni, Swarupa, Lewandowski, Thomas, Van Aller, Glenn S., Zonis, Rimma, Ward, Paris, Campobasso, Nino

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations von McCabe, Michael T., Ott, Heidi M., Ganji, Gopinath, Korenchuk, Susan, Thompson, Christine, Van Aller, Glenn S., Liu, Yan, Graves, Alan P., III, Anthony Della Pietra, Diaz, Elsie, LaFrance, Louis V., Mellinger, Mark, Duquenne, Celine, Tian, Xinrong, Kruger, Ryan G., McHugh, Charles F., Brandt, Martin, Miller, William H., Dhanak, Dashyant, Verma, Sharad K., Tummino, Peter J., Creasy, Caretha L.

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Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-d]imidazole Thrombopoietin Mimics von Duffy, Kevin J, Price, Alan T, Delorme, Evelyne, Dillon, Susan B, Duquenne, Celine, Erickson-Miller, Connie, Giampa, Leslie, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Liu, Nannan, Miller, Stephen G, Rosen, Jon, Shaw, Anthony N, Smith, Heather, Wiggall, Kenneth J, Zhang, Lihua, Luengo, Juan I

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Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors von Medina, Jesús R, Becker, Christopher J, Blackledge, Charles W, Duquenne, Celine, Feng, Yanhong, Grant, Seth W, Heerding, Dirk, Li, William H, Miller, William H, Romeril, Stuart P, Scherzer, Daryl, Shu, Arthur, Bobko, Mark A, Chadderton, Antony R, Dumble, Melissa, Gardiner, Christine M, Gilbert, Seth, Liu, Qi, Rabindran, Sridhar K, Sudakin, Valery, Xiang, Hong, Brady, Pat G, Campobasso, Nino, Ward, Paris, Axten, Jeffrey M

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Abstract 5379: A potent EZH2 inhibitor exhibits long residence time and anti-tumor activity von Ott, Heidi, van Aller, Glenn, Ward, Jessica, Le, BaoChau, Rominger, Cynthia, Foley, James, Korenchuk, Susan, McHugh, Charles, Butticello, Michael, Blackledge, Charles, Brackley, James, Burgess, Joelle, Duquenne, Celine, Johnson, Neil, Kasparec, Jiri, LaFrance, Louis, Li, Mei, McNulty, Kenneth, Newlander, Kenneth, Romeril, Stuart, Schmidt, Stanley, Schulz, Mark, Su, Dai-Shi, Suarez, Dominic, Tian, Xinrong, Carpenter, Christopher, Luengo, Juan, Kruger, Ryan, Knight, Steven, McCabe, Michael T.

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Abstract 3260: Identification and synthesis of benzimidazole carboxamides as potent inhibitors of focal adhesion kinase (FAK) von Verma, Sharad K., Leber, Jack D., LaFrance, Louis V., Li, Mei, Duquenne, Celine, Cui, Guanglei, Miller, William H.

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Rapid synthesis of diversely functionalized 3,4,7-trisubstituted indoles von Grant, Seth W., Gallagher, Timothy F., Bobko, Mark A., Duquenne, Celine, Axten, Jeffrey M.

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Novel applications of convertible isonitriles for the synthesis of mono and bicyclic γ-lactams via a UDC strategy von Hulme, Christopher, Ma, Liang, Cherrier, Marie-Pierre, Romano, Joseph J, Morton, George, Duquenne, Celine, Salvino, Joseph, Labaudiniere, Richard

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Abstract 2939: Discovery and synthesis of highly potent and selective small molecule inhibitors of the histone methyltransferase EZH2 von Verma, Sharad K., LaFrance, Louis V., Tian, Xinrong, Newlander, Ken, Duquenne, Céline, Suarez, Dominic, Knight, Steven D., Burgess, Joelle, Brackley, James, Johnson, Neil W., Graves, Alan P., Mellinger, Mark, Romeril, Stuart, Grant, Seth W., Scherzer, Daryl, Shu, Art, Creasy, Caretha L., Kruger, Ryan, Diaz, Elsie, Le, Baochau, Thompson, Christine, Morgan-Ott, Heidi, McCabe, Michael T., McHugh, Charles F., Miller, William H., Tummino, Peter, Dhanak, Dash

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Electrosynthesis of α-Arylated β-Substituted Cyclopropylphosphonates. Synthesis of a Phosphonic Analogue of Minalcipran von Duquenne, Céline, Goumain, Sophie, Jubault, Philippe, Feasson, Christian, Quirion, Jean-Charles

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ChemInform Abstract: Rapid Synthesis of Diversely Functionalized 3,4,7-Trisubstituted Indoles von Grant, Seth W., Gallagher, Timothy F., Bobko, Mark A., Duquenne, Celine, Axten, Jeffrey M.

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ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS von VERMA, SHARAD, KUMAR, BURGESS, JOELLE, LORRAINE, KNIGHT, STEVEN, DAVID, NEWLANDER, KENNETH, ALLEN, MILLER, WILLIAM, HENRY, DUQUENNE, CELINE

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ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS von NEWLANDER KENNETH ALLEN, DUQUENNE CELINE, KNIGHT STEVEN DAVID, BURGESS JOELLE LORRAINE, MILLER WILLIAM HENRY, VERMA SHARAD KUMAR

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Indazoles von TIAN XINRONG, JOHNSON NEIL, LAFRANCE LOUIS, NEWLANDER KENNETH, KNIGHT STEVEN D, DUQUENNE CELINE, ROUSE MEAGAN B, MILLER WILLIAM H, VERMA SHARAD KUMAR, ROMERIL STUART

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INDAZOLES von LAFRANCE, LOUIS, TIAN, XINRONG, VERMA, SHARAD, KUMAR, ROMERIL, STUART, JOHNSON, NEIL, ROUSE, MEAGAN, B, KNIGHT, STEVEN, D, NEWLANDER, KENNETH, MILLER, WILLIAM, H, DUQUENNE, CELINE

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ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS von VERMA, SHARAD, KUMAR, BURGESS, JOELLE, LORRAINE, KNIGHT, STEVEN, DAVID, NEWLANDER, KENNETH, ALLEN, MILLER, WILLIAM, HENRY, DUQUENNE, CELINE

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INDAZOLES von TIAN XINRONG, JOHNSON NEIL, LAFRANCE LOUIS, NEWLANDER KENNETH, KNIGHT STEVEN D, DUQUENNE CELINE, ROUSE MEAGAN B, MILLER WILLIAM H, VERMA SHARAD KUMAR, ROMERIL STUART

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Indazoles von TIAN XINRONG, JOHNSON NEIL, LAFRANCE LOUIS, NEWLANDER KENNETH, KNIGHT STEVEN D, DUQUENNE CELINE, ROUSE MEAGAN B, MILLER WILLIAM H, VERMA SHARAD KUMAR, ROMERIL STUART

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