Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma von Jühling, Frank, Hamdane, Nourdine, Crouchet, Emilie, Li, Shen, El Saghire, Houssein, Mukherji, Atish, Fujiwara, Naoto, Oudot, Marine A, Thumann, Christine, Saviano, Antonio, Roca Suarez, Armando Andres, Goto, Kaku, Masia, Ricard, Sojoodi, Mozhdeh, Arora, Gunisha, Aikata, Hiroshi, Ono, Atsushi, Tabrizian, Parissa, Schwartz, Myron, Polyak, Stephen J, Davidson, Irwin, Schmidl, Christian, Bock, Christoph, Schuster, Catherine, Chayama, Kazuaki, Pessaux, Patrick, Tanabe, Kenneth K, Hoshida, Yujin, Zeisel, Mirjam B, Duong, François HT, Fuchs, Bryan C, Baumert, Thomas F

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Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment von Roehlen, Natascha, Muller, Marion, Nehme, Zeina, Crouchet, Emilie, Jühling, Frank, Del Zompo, Fabio, Cherradi, Sara, Duong, Francois H.T., Almeida, Nuno, Saviano, Antonio, Fernández-Vaquero, Mirian, Riedl, Tobias, El Saghire, Houssein, Durand, Sarah C., Ponsolles, Clara, Oudot, Marine A., Martin, Romain, Brignon, Nicolas, Felli, Emanuele, Pessaux, Patrick, Lallement, Antonin, Davidson, Irwin, Bandiera, Simonetta, Thumann, Christine, Marchand, Patrice, Moll, Solange, Nicolay, Brandon, Bardeesy, Nabeel, Hoshida, Yujin, Heikenwälder, Mathias, Iacone, Roberto, Toso, Alberto, Meyer, Markus, Elson, Greg, Schweighoffer, Tamas, Teixeira, Geoffrey, Zeisel, Mirjam B., Laquerriere, Patrice, Lupberger, Joachim, Schuster, Catherine, Mailly, Laurent, Baumert, Thomas F.

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Epidermal growth factor receptor signaling impairs the antiviral activity of interferon‐alpha von Lupberger, Joachim, Duong, François H.T., Fofana, Isabel, Zona, Laetitia, Xiao, Fei, Thumann, Christine, Durand, Sarah C., Pessaux, Patrick, Zeisel, Mirjam B., Heim, Markus H., Baumert, Thomas F.

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Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis von Brenig, Robert, Pop, Oltin T, Triantafyllou, Evangelos, Geng, Anne, Singanayagam, Arjuna, Perez-Shibayama, Christian, Besse, Lenka, Cupovic, Jovana, Künzler, Patrizia, Boldanova, Tuyana, Brand, Stephan, Semela, David, Duong, François Ht, Weston, Christopher J, Ludewig, Burkhard, Heim, Markus H, Wendon, Julia, Antoniades, Charalambos G, Bernsmeier, Christine

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IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction von Bibert, Stéphanie, Roger, Thierry, Calandra, Thierry, Bochud, Murielle, Cerny, Andreas, Semmo, Nasser, Duong, François H T, Gerlach, Tilman, Malinverni, Raffaele, Moradpour, Darius, Negro, Francesco, Müllhaupt, Beat, Bochud, Pierre-Yves

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Interferon signaling and treatment outcome in chronic hepatitis C von Sarasin-Filipowicz, Magdalena, Oakeley, Edward J, Duong, Francois H.T, Christen, Verena, Terracciano, Luigi, Filipowicz, Witold, Heim, Markus H

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Vitamin D receptor and Jak-STAT signaling crosstalk results in calcitriol-mediated increase of hepatocellular response to IFN-α von Lange, Christian M, Gouttenoire, Jérôme, Duong, François H T, Morikawa, Kenichi, Heim, Markus H, Moradpour, Darius

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Interferon‐β and interferon‐λ signaling is not affected by interferon‐induced refractoriness to interferon‐α in vivo von Makowska, Zuzanna, Duong, Francois H. T., Trincucci, Gaia, Tough, David F., Heim, Markus H.

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Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53 von Duong, François H T, Dill, Michael T, Matter, Matthias S, Makowska, Zuzanna, Calabrese, Diego, Dietsche, Tanja, Ketterer, Sylvia, Terracciano, Luigi, Heim, Markus H

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Hepatitis C virus–induced up‐regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair von Duong, Francois H. T., Christen, Verena, Lin, Shanshan, Heim, Markus H.

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S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse von Filipowicz, Magdalena, Bernsmeier, Christine, Terracciano, Luigi, Duong, Francois H T, Heim, Markus H

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Upregulation of Protein Phosphatase 2Ac by Hepatitis C Virus Modulates NS3 Helicase Activity through Inhibition of Protein Arginine Methyltransferase 1 von Duong, Francois H T, Christen, Verena, Berke, Jan Martin, Penna, Sabina Hernandez, Moradpour, Darius, Heim, Markus H

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Interferon lambda 4 can directly activate human CD19 + B cells and CD8 + T cells von Coto-Llerena, Mairene, Lepore, Marco, Spagnuolo, Julian, Di Blasi, Daniela, Calabrese, Diego, Suslov, Aleksei, Bantug, Glenn, Duong, Francois Ht, Terracciano, Luigi M, De Libero, Gennaro, Heim, Markus H

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CS4-5 IFN stimulated gene expression in the liver is a better predictor of treatment response in chronic hepatitis C than the IL28B (IFNλ3) genotype von Dill, Michael T., Duong, Francois H.T., Vogt, Julia E., Stéphanie Bibert, Pierre-Yves Bochud, Luigi Terracciano, Andreas Papassotiropoulos, Volker Roth, Heim, Markus H.

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ANTIVIRAL THERAPY von SARASIN-FILIPOWICZ MAGDALENA, FILIPOWICZ WITOLD, DUONG FRANCOIS HT, HEIM MARKUS, OAKELEY EDWARD

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