Beyond GWASs: Illuminating the Dark Road from Association to Function von Edwards, Stacey L., Beesley, Jonathan, French, Juliet D., Dunning, Alison M.

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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study von Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M

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Shortened telomere length is associated with increased risk of cancer: a meta-analysis von Ma, Hongxia, Zhou, Ziyuan, Wei, Sheng, Liu, Zhensheng, Pooley, Karen A, Dunning, Alison M, Svenson, Ulrika, Roos, Göran, Hosgood, 3rd, H Dean, Shen, Min, Wei, Qingyi

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Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype von Barnett, Gillian C., West, Catherine M. L., Dunning, Alison M., Elliott, Rebecca M., Coles, Charlotte E., Pharoah, Paul D. P., Burnet, Neil G.

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Reproducibility of telomere length assessment: an international collaborative study von Martin-Ruiz, Carmen M, Baird, Duncan, Roger, Laureline, Boukamp, Petra, Krunic, Damir, Cawthon, Richard, Dokter, Martin M, van der Harst, Pim, Bekaert, Sofie, de Meyer, Tim, Roos, Goran, Svenson, Ulrika, Codd, Veryan, Samani, Nilesh J, McGlynn, Liane, Shiels, Paul G, Pooley, Karen A, Dunning, Alison M, Cooper, Rachel, Wong, Andrew, Kingston, Andrew, von Zglinicki, Thomas

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Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor von Litchfield, Kevin, Levy, Max, Orlando, Giulia, Loveday, Chey, Law, Philip J, Migliorini, Gabriele, Holroyd, Amy, Broderick, Peter, Karlsson, Robert, Haugen, Trine B, Kristiansen, Wenche, Nsengimana, Jérémie, Fenwick, Kerry, Assiotis, Ioannis, Kote-Jarai, ZSofia, Dunning, Alison M, Muir, Kenneth, Peto, Julian, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Orr, Nick, Pashayan, Nora, Bishop, D Timothy, Reid, Alison, Huddart, Robert A, Shipley, Janet, Grotmol, Tom, Wiklund, Fredrik, Houlston, Richard S, Turnbull, Clare

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Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis von Nead, Kevin T, Sharp, Stephen J, Thompson, Deborah J, Painter, Jodie N, Savage, David B, Semple, Robert K, Barker, Adam, Perry, John R B, Attia, John, Dunning, Alison M, Easton, Douglas F, Holliday, Elizabeth, Lotta, Luca A, O'Mara, Tracy, McEvoy, Mark, Pharoah, Paul D P, Scott, Rodney J, Spurdle, Amanda B, Langenberg, Claudia, Wareham, Nicholas J, Scott, Robert A

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A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1 von Fachal, Laura, Gómez-Caamaño, Antonio, Barnett, Gillian C, Peleteiro, Paula, Carballo, Ana M, Calvo-Crespo, Patricia, Kerns, Sarah L, Sánchez-García, Manuel, Lobato-Busto, Ramón, Dorling, Leila, Elliott, Rebecca M, Dearnaley, David P, Sydes, Matthew R, Hall, Emma, Burnet, Neil G, Carracedo, Ángel, Rosenstein, Barry S, West, Catharine M L, Dunning, Alison M, Vega, Ana

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Most common 'sporadic' cancers have a significant germline genetic component von Lu, Yi, Ek, Weronica E, Whiteman, David, Vaughan, Thomas L, Spurdle, Amanda B, Easton, Douglas F, Pharoah, Paul D, Thompson, Deborah J, Dunning, Alison M, Hayward, Nicholas K, Chenevix-Trench, Georgia, Macgregor, Stuart

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Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study von Barnett, Gillian C, Dr, Coles, Charlotte E, PhD, Elliott, Rebecca M, MRes, Baynes, Caroline, Luccarini, Craig, BSc, Conroy, Don, Wilkinson, Jennifer S, BSc, Tyrer, Jonathan, PhD, Misra, Vivek, MB BS, Platte, Radka, BSc, Gulliford, Sarah L, PhD, Sydes, Matthew R, MSc, Hall, Emma, PhD, Bentzen, Søren M, Prof, Dearnaley, David P, Prof, Burnet, Neil G, PhD, Pharoah, Paul DP, PhD, Dunning, Alison M, PhD, West, Catharine ML, Prof

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Chromatin interactome mapping at 139 independent breast cancer risk signals von Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lima, Luize G, Hillman, Kristine M, Kaufmann, Susanne, Tuano, Natasha, Hussein, Nehal, Ham, Sunyoung, Mukhopadhyay, Pamela, Kazakoff, Stephen, Lee, Jason S, Michailidou, Kyriaki, Barnes, Daniel R, Antoniou, Antonis C, Fachal, Laura, Dunning, Alison M, Easton, Douglas F, Waddell, Nicola, Rosenbluh, Joseph, Möller, Andreas, Chenevix-Trench, Georgia, French, Juliet D, Edwards, Stacey L

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Non-coding RNAs underlie genetic predisposition to breast cancer von Moradi Marjaneh, Mahdi, Beesley, Jonathan, O'Mara, Tracy A, Mukhopadhyay, Pamela, Koufariotis, Lambros T, Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M, Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E, McCart Reed, Amy E, Ferguson, Kaltin, Saunus, Jodi M, Lakhani, Sunil R, Barnes, Daniel R, Antoniou, Antonis C, Dinger, Marcel E, Waddell, Nicola, Easton, Douglas F, Dunning, Alison M, Chenevix-Trench, Georgia, Edwards, Stacey L, French, Juliet D

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From candidate gene studies to GWAS and post-GWAS analyses in breast cancer von Fachal, Laura, Dunning, Alison M

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Association studies for finding cancer-susceptibility genetic variants von Pharoah, Paul D. P., Dunning, Alison M., Ponder, Bruce A. J., Easton, Douglas F.

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Telomere length in prospective and retrospective cancer case-control studies von Pooley, Karen A, Sandhu, Manjinder S, Tyrer, Jonathan, Shah, Mitul, Driver, Kristy E, Luben, Robert N, Bingham, Sheila A, Ponder, Bruce A J, Pharoah, Paul D P, Khaw, Kay-Tee, Easton, Douglas F, Dunning, Alison M

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Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification von Ho, Peh Joo, Ho, Weang Kee, Khng, Alexis J, Yeoh, Yen Shing, Tan, Benita Kiat-Tee, Tan, Ern Yu, Lim, Geok Hoon, Tan, Su-Ming, Tan, Veronique Kiak Mien, Yip, Cheng-Har, Mohd-Taib, Nur-Aishah, Wong, Fuh Yong, Lim, Elaine Hsuen, Ngeow, Joanne, Chay, Wen Yee, Leong, Lester Chee Hao, Yong, Wei Sean, Seah, Chin Mui, Tang, Siau Wei, Ng, Celene Wei Qi, Yan, Zhiyan, Lee, Jung Ah, Rahmat, Kartini, Islam, Tania, Hassan, Tiara, Tai, Mei-Chee, Khor, Chiea Chuen, Yuan, Jian-Min, Koh, Woon-Puay, Sim, Xueling, Dunning, Alison M, Bolla, Manjeet K, Antoniou, Antonis C, Teo, Soo-Hwang, Li, Jingmei, Hartman, Mikael

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STROGAR – STrengthening the Reporting Of Genetic Association studies in Radiogenomics von Kerns, Sarah L, Ruysscher, Dirk de, Andreassen, Christian N, Azria, David, Barnett, Gillian C, Chang-Claude, Jenny, Davidson, Susan, Deasy, Joseph O, Dunning, Alison M, Ostrer, Harry, Rosenstein, Barry S, West, Catharine M.L, Bentzen, Søren M

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Targeted Resequencing of the Coding Sequence of 38 Genes Near Breast Cancer GWAS Loci in a Large Case-Control Study von Decker, Brennan, Allen, Jamie, Luccarini, Craig, Pooley, Karen A, Shah, Mitul, Bolla, Manjeet K, Wang, Qin, Ahmed, Shahana, Baynes, Caroline, Conroy, Don M, Brown, Judith, Luben, Robert, Ostrander, Elaine A, Pharoah, Paul D P, Dunning, Alison M, Easton, Douglas F

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A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding von Painter, Jodie N., Kaufmann, Susanne, O’Mara, Tracy A., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., Spurdle, Amanda B., Edwards, Stacey L.

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Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer von Kerns, Sarah L., Dorling, Leila, Fachal, Laura, Bentzen, Søren, Pharoah, Paul D.P., Barnes, Daniel R., Gómez-Caamaño, Antonio, Carballo, Ana M., Dearnaley, David P., Peleteiro, Paula, Gulliford, Sarah L., Hall, Emma, Michailidou, Kyriaki, Carracedo, Ángel, Sia, Michael, Stock, Richard, Stone, Nelson N., Sydes, Matthew R., Tyrer, Jonathan P., Ahmed, Shahana, Parliament, Matthew, Ostrer, Harry, Rosenstein, Barry S., Vega, Ana, Burnet, Neil G., Dunning, Alison M., Barnett, Gillian C., West, Catharine M.L.

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