Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants von Satterstrom, F. Kyle, Walters, Raymond K., Singh, Tarjinder, Wigdor, Emilie M., Lescai, Francesco, Demontis, Ditte, Kosmicki, Jack A., Grove, Jakob, Stevens, Christine, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Palmer, Duncan S., Maller, Julian B., Nordentoft, Merete, Mors, Ole, Robinson, Elise B., Hougaard, David M., Werge, Thomas M., Bo Mortensen, Preben, Neale, Benjamin M., Børglum, Anders D., Daly, Mark J.

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The impact of non-additive genetic associations on age-related complex diseases von Guindo-Martínez, Marta, Amela, Ramon, Bonàs-Guarch, Silvia, Puiggròs, Montserrat, Salvoro, Cecilia, Miguel-Escalada, Irene, Carey, Caitlin E., Cole, Joanne B., Rüeger, Sina, Atkinson, Elizabeth, Leong, Aaron, Sanchez, Friman, Ramon-Cortes, Cristian, Ejarque, Jorge, Palmer, Duncan S., Kurki, Mitja, Aragam, Krishna, Florez, Jose C., Badia, Rosa M., Mercader, Josep M., Torrents, David

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Analysis of genetic dominance in the UK Biobank von Palmer, Duncan S, Zhou, Wei, Abbott, Liam, Wigdor, Emilie M, Baya, Nikolas, Churchhouse, Claire, Seed, Cotton, Poterba, Tim, King, Daniel, Kanai, Masahiro, Bloemendal, Alex, Neale, Benjamin M

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A data harmonization pipeline to leverage external controls and boost power in GWAS von Chen, Danfeng, Tashman, Katherine, Palmer, Duncan S, Neale, Benjamin, Roeder, Kathryn, Bloemendal, Alex, Churchhouse, Claire, Ke, Zheng Tracy

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Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records von Venkatesh, Samvida S., Ganjgahi, Habib, Palmer, Duncan S., Coley, Kayesha, Linchangco, Gregorio V., Hui, Qin, Wilson, Peter, Ho, Yuk-Lam, Cho, Kelly, Arumäe, Kadri, Wittemans, Laura B. L., Nellåker, Christoffer, Vainik, Uku, Sun, Yan V., Holmes, Chris, Lindgren, Cecilia M., Nicholson, George

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A naturally protective epitope of limited variability as an influenza vaccine target von Thompson, Craig P., Lourenço, José, Walters, Adam A., Obolski, Uri, Edmans, Matthew, Palmer, Duncan S., Kooblall, Kreepa, Carnell, George W., O’Connor, Daniel, Bowden, Thomas A., Pybus, Oliver G., Pollard, Andrew J., Temperton, Nigel J., Lambe, Teresa, Gilbert, Sarah C., Gupta, Sunetra

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Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes von Karczewski, Konrad J., Solomonson, Matthew, Chao, Katherine R., Goodrich, Julia K., Tiao, Grace, Lu, Wenhan, Riley-Gillis, Bridget M., Tsai, Ellen A., Kim, Hye In, Zheng, Xiuwen, Rahimov, Fedik, Esmaeeli, Sahar, Grundstad, A. Jason, Reppell, Mark, Waring, Jeff, Jacob, Howard, Sexton, David, Bronson, Paola G., Chen, Xing, Hu, Xinli, Goldstein, Jacqueline I., King, Daniel, Vittal, Christopher, Poterba, Timothy, Palmer, Duncan S., Churchhouse, Claire, Howrigan, Daniel P., Zhou, Wei, Watts, Nicholas A., Nguyen, Kevin, Nguyen, Huy, Mason, Cara, Farnham, Christopher, Tolonen, Charlotte, Gauthier, Laura D., Gupta, Namrata, MacArthur, Daniel G., Rehm, Heidi L., Seed, Cotton, Philippakis, Anthony A., Daly, Mark J., Davis, J. Wade, Runz, Heiko, Miller, Melissa R., Neale, Benjamin M.

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Mapping the drivers of within-host pathogen evolution using massive data sets von Palmer, Duncan S., Turner, Isaac, Fidler, Sarah, Frater, John, Goedhals, Dominique, Goulder, Philip, Huang, Kuan-Hsiang Gary, Oxenius, Annette, Phillips, Rodney, Shapiro, Roger, Vuuren, Cloete van, McLean, Angela R., McVean, Gil

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Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank von Lassen, Frederik H., Venkatesh, Samvida S., Baya, Nikolas, Hill, Barney, Zhou, Wei, Bloemendal, Alex, Neale, Benjamin M., Kessler, Benedikt M., Whiffin, Nicola, Lindgren, Cecilia M., Palmer, Duncan S.

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Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation von Carey, Caitlin E., Shafee, Rebecca, Wedow, Robbee, Elliott, Amanda, Palmer, Duncan S., Compitello, John, Kanai, Masahiro, Abbott, Liam, Schultz, Patrick, Karczewski, Konrad J., Bryant, Samuel C., Cusick, Caroline M., Churchhouse, Claire, Howrigan, Daniel P., King, Daniel, Davey Smith, George, Neale, Benjamin M., Walters, Raymond K., Robinson, Elise B.

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Cytotoxic T-Lymphocyte Escape Mutations Identified by HLA Association Favor Those Which Escape and Revert Rapidly von FRYER, Helen R, FRATER, John, DUDA, Anna, PALMER, Duncan, PHILLIPS, Rodney E, MCLEAN, Angela R

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The financial survival probability of living annuitants von Palmer, Duncan, Krige, Niel

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Real age-adjusted life expectancy von Palmer, Duncan, Krige, Niel

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Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries von Weale, Michael E., Riveros-Mckay, Fernando, Selzam, Saskia, Seth, Priyanka, Moore, Rachel, Tarran, William A., Gradovich, Eva, Giner-Delgado, Carla, Palmer, Duncan, Wells, Daniel, Saffari, Ayden, Sivley, R. Michael, Lachapelle, Alexander S., Wand, Hannah, Clarke, Shoa L., Knowles, Joshua W., O'Sullivan, Jack W., Ashley, Euan A., McVean, Gil, Plagnol, Vincent, Donnelly, Peter

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CONTEXTUALIZING PSYCHIATRIC CONSTRUCTS AND THEIR RELATIONSHIPS TO PUBLIC HEALTH VIA BIOBANK-SCALE FACTOR ANALYSIS von Carey, Caitlin, Shafee, Rebecca, Wedow, Robbee, Palmer, Duncan, Abbott, Liam, Howrigan, Daniel, Churchhouse, Claire, Neale, Benjamin, Walters, Raymond, Robinson, Elise

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A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release von Thompson, Deborah J, Wells, Daniel, Selzam, Saskia, Peneva, Iliana, Moore, Rachel, Sharp, Kevin, Tarran, William A, Beard, Edward J, Riveros-Mckay, Fernando, Giner-Delgado, Carla, Palmer, Duncan, Seth, Priyanka, Harrison, James, Futema, Marta, McVean, Gil, Plagnol, Vincent, Donnelly, Peter, Weale, Michael E

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A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score von Thompson, Deborah J, Wells, Daniel, Selzam, Saskia, Peneva, Iliana, Moore, Rachel, Sharp, Kevin, Tarran, William A, Beard, Edward J, Riveros-Mckay, Fernando, Giner-Delgado, Carla, Palmer, Duncan, Seth, Priyanka, Harrison, James, Futema, Marta, McVean, Gil, Plagnol, Vincent, Donnelly, Peter, Weale, Michael E

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Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity von Rajagopal, Veera M., Ganna, Andrea, Coleman, Jonathan R. I., Allegrini, Andrea, Voloudakis, Georgios, Grove, Jakob, Als, Thomas D., Horsdal, Henriette T., Petersen, Liselotte, Appadurai, Vivek, Schork, Andrew, Buil, Alfonso, Bulik, Cynthia M., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Hougaard, David M., Mors, Ole, Nordentoft, Merete, Werge, Thomas, Mortensen, Preben Bo, Breen, Gerome, Roussos, Panos, Plomin, Robert, Agerbo, Esben, Børglum, Anders D., Demontis, Ditte

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Large-scale meta-analysis highlights the hypothalamic-pituitary-gonadal axis in the genetic regulation of menstrual cycle length von Laisk, Triin, Kukuškina, Viktorija, Palmer, Duncan, Laber, Samantha, Chen, Chia-Yen, Ferreira, Teresa, Rahmioglu, Nilufer, Zondervan, Krina, Becker, Christian, Smoller, Jordan W, Lippincott, Margaret, Salumets, Andres, Granne, Ingrid, Seminara, Stephanie, Neale, Benjamin, Mägi, Reedik, Lindgren, Cecilia M

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Elevated polygenic burden for autism is associated with differential DNA methylation at birth von Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V, Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D, Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M, Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan

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