Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease von Khan, Usman A, Liu, Li, Provenzano, Frank A, Berman, Diego E, Profaci, Caterina P, Sloan, Richard, Mayeux, Richard, Duff, Karen E, Small, Scott A

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Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases von Myeku, Natura, Duff, Karen E.

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Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease von Fu, Hongjun, Rodriguez, Gustavo A., Herman, Mathieu, Emrani, Sheina, Nahmani, Eden, Barrett, Geoffrey, Figueroa, Helen Y., Goldberg, Eliana, Hussaini, S. Abid, Duff, Karen E.

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Neuronal activity enhances tau propagation and tau pathology in vivo von Wu, Jessica W, Hussaini, S Abid, Bastille, Isle M, Rodriguez, Gustavo A, Mrejeru, Ana, Rilett, Kelly, Sanders, David W, Cook, Casey, Fu, Hongjun, Boonen, Rick A C M, Herman, Mathieu, Nahmani, Eden, Emrani, Sheina, Figueroa, Y Helen, Diamond, Marc I, Clelland, Catherine L, Wray, Selina, Duff, Karen E

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Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons von Wu, Jessica W., Herman, Mathieu, Liu, Li, Simoes, Sabrina, Acker, Christopher M., Figueroa, Helen, Steinberg, Joshua I., Margittai, Martin, Kayed, Rakez, Zurzolo, Chiara, Di Paolo, Gilbert, Duff, Karen E.

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Mechanisms of protein seeding in neurodegenerative diseases von Walker, Lary C, Diamond, Marc I, Duff, Karen E, Hyman, Bradley T

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Selective vulnerability in neurodegenerative diseases von Fu, Hongjun, Hardy, John, Duff, Karen E.

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Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A beta and tau pathology in the hippocampus von Rodriguez, Gustavo A., Barrett, Geoffrey M., Duff, Karen E., Hussaini, S. Abid

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Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology von Nuriel, Tal, Angulo, Sergio L., Khan, Usman, Ashok, Archana, Chen, Qiuying, Figueroa, Helen Y., Emrani, Sheina, Liu, Li, Herman, Mathieu, Barrett, Geoffrey, Savage, Valerie, Buitrago, Luna, Cepeda-Prado, Efrain, Fung, Christine, Goldberg, Eliana, Gross, Steven S., Hussaini, S. Abid, Moreno, Herman, Small, Scott A., Duff, Karen E.

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Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo von Congdon, Erin E., Wu, Jessica W., Myeku, Natura, Figueroa, Yvette H., Herman, Mathieu, Marinec, Paul S., Gestwicki, Jason E., Dickey, Chad A., Yu, W. Haung, Duff, Karen E.

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The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo von Nuriel, Tal, Peng, Katherine Y, Ashok, Archana, Dillman, Allissa A, Figueroa, Helen Y, Apuzzo, Justin, Ambat, Jayanth, Levy, Efrat, Cookson, Mark R, Mathews, Paul M, Duff, Karen E

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In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease von Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L., Sanchez, Justin S., Xu, Catherine K., Duff, Karen E., Johnson, Keith A., Rowe, James B., Hyman, Bradley T., Knowles, Tuomas P. J., Klenerman, David

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Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits von Oliveira, Tiago Gil, Chan, Robin B, Tian, Huasong, Laredo, Mikael, Shui, Guanghou, Staniszewski, Agnieszka, Zhang, Hong, Wang, Lili, Kim, Tae-Wan, Duff, Karen E, Wenk, Markus R, Arancio, Ottavio, Di Paolo, Gilbert

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Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease von Chen, Shuo, Chang, Yuzhou, Li, Liangping, Acosta, Diana, Li, Yang, Guo, Qi, Wang, Cankun, Turkes, Emir, Morrison, Cody, Julian, Dominic, Hester, Mark E, Scharre, Douglas W, Santiskulvong, Chintda, Song, Sarah XueYing, Plummer, Jasmine T, Serrano, Geidy E, Beach, Thomas G, Duff, Karen E, Ma, Qin, Fu, Hongjun

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Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia von Planel, Emmanuel, Richter, Karl E. G, Nolan, Charles E, Finley, James E, Liu, Li, Wen, Yi, Krishnamurthy, Pavan, Herman, Mathieu, Wang, Lili, Schachter, Joel B, Nelson, Robert B, Lau, Lit-Fui, Duff, Karen E

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Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice von Miranda, André Miguel, Ashok, Archana, Chan, Robin Barry, Zhou, Bowen, Xu, Yimeng, McIntire, Laura Beth, Area-Gomez, Estela, Di Paolo, Gilbert, Duff, Karen E., Oliveira, Tiago Gil, Nuriel, Tal

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Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction von Alldred, Melissa J, Duff, Karen E, Ginsberg, Stephen D

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Tau-targeting antibody therapies: too late, wrong epitope or wrong target? von Jabbari, Edwin, Duff, Karen E.

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3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Age... von Fu, Hongjun, Hussaini, S Abid, Wegmann, Susanne, Profaci, Caterina, Daniels, Jacob D, Herman, Mathieu, Emrani, Sheina, Figueroa, Helen Y, Hyman, Bradley T, Davies, Peter, Duff, Karen E

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Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia von Planel, Emmanuel, Bretteville, Alexis, Liu, Li, Virag, Laszlo, Du, Angela L, Yu, Wai Haung, Dickson, Dennis W, Whittington, Robert A, Duff, Karen E

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