MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition von Fell, Matthew J., Mirescu, Christian, Basu, Kallol, Cheewatrakoolpong, Boonlert, DeMong, Duane E., Ellis, J. Michael, Hyde, Lynn A., Lin, Yinghui, Markgraf, Carrie G., Mei, Hong, Miller, Michael, Poulet, Frederique M., Scott, Jack D., Smith, Michelle D., Yin, Zhizhang, Zhou, Xiaoping, Parker, Eric M., Kennedy, Matthew E., Morrow, John A.

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Asymmetric Synthesis of (2S,3R)-Capreomycidine and the Total Synthesis of Capreomycin IB von DeMong, Duane E, Williams, Robert M

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Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity von Scott, Jack D, DeMong, Duane E, Greshock, Thomas J, Basu, Kallol, Dai, Xing, Harris, Joel, Hruza, Alan, Li, Sarah W, Lin, Sue-Ing, Liu, Hong, Macala, Megan K, Hu, Zhiyong, Mei, Hong, Zhang, Honglu, Walsh, Paul, Poirier, Marc, Shi, Zhi-Cai, Xiao, Li, Agnihotri, Gautam, Baptista, Marco A. S, Columbus, John, Fell, Matthew J, Hyde, Lynn A, Kuvelkar, Reshma, Lin, Yinghui, Mirescu, Christian, Morrow, John A, Yin, Zhizhang, Zhang, Xiaoping, Zhou, Xiaoping, Chang, Ronald K, Embrey, Mark W, Sanders, John M, Tiscia, Heather E, Drolet, Robert E, Kern, Jonathan T, Sur, Sylvie M, Renger, John J, Bilodeau, Mark T, Kennedy, Matthew E, Parker, Eric M, Stamford, Andrew W, Nargund, Ravi, McCauley, John A, Miller, Michael W

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 H -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease von Candito, David A, Simov, Vladimir, Gulati, Anmol, Kattar, Solomon, Chau, Ryan W, Lapointe, Blair T, Methot, Joey L, DeMong, Duane E, Graham, Thomas H, Kurukulasuriya, Ravi, Keylor, Mitchell H, Tong, Ling, Morriello, Gregori J, Acton, John J, Pio, Barbara, Liu, Weiguo, Scott, Jack D, Ardolino, Michael J, Martinot, Theodore A, Maddess, Matthew L, Yan, Xin, Gunaydin, Hakan, Palte, Rachel L, McMinn, Spencer E, Nogle, Lisa, Yu, Hongshi, Minnihan, Ellen C, Lesburg, Charles A, Liu, Ping, Su, Jing, Hegde, Laxminarayan G, Moy, Lily Y, Woodhouse, Janice D, Faltus, Robert, Xiong, Tina, Ciaccio, Paul, Piesvaux, Jennifer A, Otte, Karin M, Kennedy, Matthew E, Bennett, David Jonathan, DiMauro, Erin F, Fell, Matthew J, Neelamkavil, Santhosh, Wood, Harold B, Fuller, Peter H, Ellis, J Michael

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A Novel Method for the Preparation of 4‑Arylimidazolones von DeMong, Duane E, Ng, Irene, Miller, Michael W, Stamford, Andrew W

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The asymmetric synthesis of (2 S ,3 R )-capreomycidine von DeMong, Duane E, Williams, Robert M

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Synthesis, Structure−Activity Relationship and in Vivo Antiinflammatory Efficacy of Substituted Dipiperidines as CCR2 Antagonists von Xia, Mingde, Hou, Cuifen, DeMong, Duane E, Pollack, Scott R, Pan, Meng, Brackley, James A, Jain, Nareshkumar, Gerchak, Chrissy, Singer, Monica, Malaviya, Ravi, Matheis, Michele, Olini, Gil, Cavender, Druie, Wachter, Michael

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1‑Heteroaryl‑1H‑Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease von Candito, David A., Simov, Vladimir, Gulati, Anmol, Kattar, Solomon, Chau, Ryan W., Lapointe, Blair T., Methot, Joey L., DeMong, Duane E., Graham, Thomas H., Kurukulasuriya, Ravi, Keylor, Mitchell H., Tong, Ling, Morriello, Gregori J., Acton, John J., Pio, Barbara, Liu, Weiguo, Scott, Jack D., Ardolino, Michael J., Martinot, Theodore A., Maddess, Matthew L., Yan, Xin, Gunaydin, Hakan, Palte, Rachel L., McMinn, Spencer E., Nogle, Lisa, Yu, Hongshi, Minnihan, Ellen C., Lesburg, Charles A., Liu, Ping, Su, Jing, Hegde, Laxminarayan G., Moy, Lily Y., Woodhouse, Janice D., Faltus, Robert, Xiong, Tina, Ciaccio, Paul, Piesvaux, Jennifer A., Otte, Karin M., Kennedy, Matthew E., Bennett, David Jonathan, DiMauro, Erin F., Fell, Matthew J., Neelamkavil, Santhosh, Wood, Harold B., Fuller, Peter H., Ellis, J. Michael

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An efficient asymmetric synthesis of (2 S,3 S)- and (2 R,3 R)-β-hydroxyornithine von DeMong, Duane E, Williams, Robert M

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Asymmetric Synthesis of (+)-Hypusine von Jain, Rajendra P, Albrecht, Brian K, DeMong, Duane E, Williams, Robert M

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A Novel Carbohydrate-Glycosphingolipid Interaction between a β-(1–3)-Glucan Immunomodulator, PGG-glucan, and Lactosylceramide of Human Leukocytes von Zimmerman, Janet W., Lindermuth, Johanna, Fish, Pamela A., Palace, Gerard P., Stevenson, Tom T., DeMong, Duane E.

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ChemInform Abstract: A Novel Method for the Preparation of 4-Arylimidazolones von DeMong, Duane E., Ng, Irene, Miller, Michael W., Stamford, Andrew W.

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COMPOSTO, COMPOSIÇÃO FARMACÊUTICA, E, MÉTODOS PARA INDUZIR UMA RESPOSTA IMUNE, PARA INDUZIR PRODUÇÃO DE INTERFERONS DE TIPO I DEPENDENTES DE STING E PARA TRATAR UM DISTÚRBIO DE PRO... von RYAN D. OTTE, MICHAEL D. ALTMAN, JARED N. CUMMING, MATTHEW A. LARSEN, MATTHEW LLOYD HILDERS, MIN LU, DUANE E. DEMONG, BRANDON D. CASH, JAMES P. JEWELL, TIMOTHY J. HENDERSON, ANDREW MARC HAIDLE, JONGWON LIM, BENJAMIN WESLEY TROTTER

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composto, composição farmacêutica, e, métodos para induzir uma resposta imune, para induzir produção de interferons de tipo i dependentes de sting e para tratar um distúrbio de pro... von RYAN D. OTTE, MICHAEL D. ALTMAN, JARED N. CUMMING, MATTHEW A. LARSEN, MATTHEW LLOYD HILDERS, MIN LU, DUANE E. DEMONG, BRANDON D. CASH, JAMES P. JEWELL, TIMOTHY J. HENDERSON, ANDREW MARC HAIDLE, JONGWON LIM, BENJAMIN WESLEY TROTTER

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The first asymmetric synthesis of (2 S)- and (2 R)-amino-3,3-dimethoxypropanoic acid von DeMong, Duane E., Williams, Robert M.

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BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS von CHILDERS Matthew Lloyd, LIM Jongwon, LARSEN Matthew, A, HAIDLE Andrew Marc, ALTMAN Michael, D, TROTTER Benjamin Wesley, DEMONG Duane, E, CUMMING Jared, N, JEWELL James, P, HENDERSON Timothy, J, CASH Brandon, D, LU Min, OTTE Ryan, D

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composto, composição farmacêutica, e, uso de um composto von Yan Guo, MICHAEL MILLER, Duane E. Demong, Christopher W. Plummer, Harry R. Chobanian, Linda L. Brockunier, William K. Hagmann, Helen Chen, Barbara Pio, Dong Xiao, Matthew J. Clements, Alejandro Crespo, Karen M. Marcantonio

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ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE THEREOF von BRILL, Zachary G, ALI, Amjad, PLUMMER, Christopher W, DEMONG, Duane E, LIM, Yeon-Hee, SU, Jing, CHRISTIAN, Alec Hiroshi, CUMMING, Jared N, RICO DUQUE, Jenny Lorena, HENNESSY, Elisabeth T, LI, Derun

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SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF von SCHNEIDER, Sebastian, E, YEUNG, Charles, S, HUANG, Chunhui, ZHENG, Xiao Mei, CANDITO, David, A, LOGAN, Kaitlyn Marie, FISCHER, Christian, FRADERA, Xavier, OTTE, Ryan, D, CHILDERS, Matthew, A, DEMONG, Duane, E, KAWAMURA, Shuhei, JEWELL, James, P, LIU, Ping

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ADENOSINE A2A AND A2B RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF von MORENO, Jesus, ALI, Amjad, PLUMMER, Christopher W, DEMONG, Duane E, CUMMING, Jared N, SATHER, Aaron C, HENNESSY, Elisabeth T, JOHNSON, Rebecca Elizabeth, LARSEN, Matthew A, KAPLAN, William P, LI, Derun, MANSOOR, Umar Faruk, DENG, Qiaolin

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