Diversity and Coverage of Structural Sublibraries Selected Using the SAGE and SCA Algorithms von Reynolds, Charles H, Tropsha, Alexander, Pfahler, Lori B, Druker, Ross, Chakravorty, Subhas, Ethiraj, G, Zheng, Weifan

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Lead Discovery Using Stochastic Cluster Analysis (SCA):  A New Method for Clustering Structurally Similar Compounds von Reynolds, Charles H, Druker, Ross, Pfahler, Lori B

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Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure von Hughes, Timothy P, Mauro, Michael J, Cortes, Jorge E, Minami, Hironobu, Rea, Delphine, DeAngelo, Daniel J, Breccia, Massimo, Goh, Yeow-Tee, Talpaz, Moshe, Hochhaus, Andreas, le Coutre, Philipp, Ottmann, Oliver, Heinrich, Michael C, Steegmann, Juan L, Deininger, Michael W.N, Janssen, Jeroen J.W.M, Mahon, Francois-Xavier, Minami, Yosuke, Yeung, David, Ross, David M, Tallman, Martin S, Park, Jae H, Druker, Brian J, Hynds, David, Duan, Yuyan, Meille, Christophe, Hourcade-Potelleret, Florence, Vanasse, K. Gary, Lang, Fabian, Kim, Dong-Wook

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Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial von Burd, Amy, Levine, Ross L., Ruppert, Amy S., Mims, Alice S., Borate, Uma, Stein, Eytan M., Patel, Prapti, Baer, Maria R., Stock, Wendy, Deininger, Michael, Blum, William, Schiller, Gary, Olin, Rebecca, Litzow, Mark, Foran, James, Lin, Tara L., Ball, Brian, Boyiadzis, Michael, Traer, Elie, Odenike, Olatoyosi, Arellano, Martha, Walker, Alison, Duong, Vu. H., Kovacsovics, Tibor, Collins, Robert, Shoben, Abigail B., Heerema, Nyla A., Foster, Matthew C., Vergilio, Jo-Anne, Brennan, Tim, Vietz, Christine, Severson, Eric, Miller, Molly, Rosenberg, Leonard, Marcus, Sonja, Yocum, Ashley, Chen, Timothy, Stefanos, Mona, Druker, Brian, Byrd, John C.

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Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles von Fröhling, Stefan, Scholl, Claudia, Levine, Ross L., Loriaux, Marc, Boggon, Titus J., Bernard, Olivier A., Berger, Roland, Döhner, Hartmut, Döhner, Konstanze, Ebert, Benjamin L., Teckie, Sewit, Golub, Todd R., Jiang, Jingrui, Schittenhelm, Marcus M., Lee, Benjamin H., Griffin, James D., Stone, Richard M., Heinrich, Michael C., Deininger, Michael W., Druker, Brian J., Gilliland, D. Gary

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Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma von Pan, Jianbo, Hu, Yingwei, Krek, Azra, Li, Yize, Chen, Lin S., Vasaikar, Suhas, Wu, Yige, Chowdhury, Shrabanti, Wyczalkowski, Matthew A., Kong, Andy, Sethuraman, Sunantha, Avtonomov, Dmitry M., Colaprico, Antonio, Cao, Song, Cho, Kyung-Cho, Kalayci, Selim, Ma, Shiyong, Ruggles, Kelly, Kawaler, Emily, Wen, Bo, Chen, Feng, Edwards, Nathan, Pierorazio, Phillip M., Pavlovich, Christian P., Brominski, Gabriel, Hsieh, James J., Lubinski, Jan, Wiznerowicz, Maciej, Kinsinger, Christopher R., Thiagarajan, Mathangi, Mesri, Mehdi, Hiltke, Tara, Ding, Li, Zhang, Zhen, Omenn, Gilbert S., Cieslik, Marcin, Nesvizhskii, Alexey I., Zhang, Hui, Hashimi, Abdul Samad, Charamut, Alyssa, Druker, Brian J., Tognon, Cristina, Mani, D.R., Rohrer, Daniel C., Tansil, Darlene, Chesla, David, Heiman, David, Wheeler, David, Chan, Doug, Demir, Emek, Wilson, George D., Liu, Hongwei, Zhou, Hua, Day, Jacob, Suh, James, Whiteaker, Jeffrey R., Eschbacher, Jennifer, Chen, Jin, Ketchum, Karen A., Rodland, Karin D., Krug, Karsten, Holloway, Kimberly, Sokoll, Lori J., Cornwell, MacIntosh, Loriaux, Marc, Anderson, Matthew, Ellis, Matthew J., Dyer, Maureen, Burke, Meghan C., Borucki, Melissa, Gillette, Michael A., Birrer, Michael J., Smith, Michael, Khan, Munziba, Roche, Nancy, Edwards, Nathan J., Vatanian, Negin, Tignor, Nicole, Piehowski, Paul, McGarvey, Peter B., Hariharan, Pushpa, Gao, Qingsong, Thangudu, Ratna R., Montgomery, Rebecca, Bremner, Ross, Liu, Ruiyang, Hong, Runyu, Payne, Samuel H., Patel, Shalin, Satpathy, Shankha, Davies, Sherri R., Patil, Snehal, Carter, Sonya, Gabriel, Stacey, Thomas, Stefani N., Carr, Steven A., Skelly, Tara, Borate, Uma, Maruvka, Yosef, Li, Zhi

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High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients von Tyner, Jeffrey W., Erickson, Heidi, Deininger, Michael W.N., Willis, Stephanie G., Eide, Christopher A., Levine, Ross L., Heinrich, Michael C., Gattermann, Norbert, Gilliland, D. Gary, Druker, Brian J., Loriaux, Marc M.

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A precision medicine classification for treatment of acute myeloid leukemia in older patients von Mims, Alice S, Kohlschmidt, Jessica, Borate, Uma, Blachly, James S, Orwick, Shelley, Eisfeld, Ann-Kathrin, Papaioannou, Dimitrios, Nicolet, Deedra, Mrόzek, Krzysztof, Stein, Eytan, Bhatnagar, Bhavana, Stone, Richard M, Kolitz, Jonathan E, Wang, Eunice S, Powell, Bayard L, Burd, Amy, Levine, Ross L, Druker, Brian J, Bloomfield, Clara D, Byrd, John C

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Entospletinib with decitabine in acute myeloid leukemia with mutant TP53 or complex karyotype: A phase 2 substudy of the Beat AML Master Trial von Duong, Vu H., Ruppert, Amy S., Mims, Alice S., Borate, Uma, Stein, Eytan M., Baer, Maria R., Stock, Wendy, Kovacsovics, Tibor, Blum, William, Arellano, Martha L., Schiller, Gary J., Olin, Rebecca L., Foran, James M., Litzow, Mark R., Lin, Tara L., Patel, Prapti A., Foster, Matthew C., Redner, Robert L., Al‐Mansour, Zeina, Cogle, Christopher R., Swords, Ronan T., Collins, Robert H., Vergilio, Jo‐Anne, Heerema, Nyla A., Rosenberg, Leonard, Yocum, Ashley O., Marcus, Sonja, Chen, Timothy, Druggan, Franchesca, Stefanos, Mona, Gana, Theophilus J., Shoben, Abigail B., Druker, Brian J., Burd, Amy, Byrd, John C., Levine, Ross L., Boyiadzis, Michael M.

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TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia von Sanda, Takaomi, Tyner, Jeffrey W, Gutierrez, Alejandro, Ngo, Vu N, Glover, Jason, Chang, Bill H, Yost, Arla, Ma, Wenxue, Fleischman, Angela G, Zhou, Wenjun, Yang, Yandan, Kleppe, Maria, Ahn, Yebin, Tatarek, Jessica, Kelliher, Michelle A, Neuberg, Donna S, Levine, Ross L, Moriggl, Richard, Müller, Mathias, Gray, Nathanael S, Jamieson, Catriona H M, Weng, Andrew P, Staudt, Louis M, Druker, Brian J, Look, A Thomas

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The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia von Levine, Ross L., Loriaux, Marc, Huntly, Brian J.P., Loh, Mignon L., Beran, Miroslav, Stoffregen, Eric, Berger, Roland, Clark, Jennifer J., Willis, Stephanie G., Nguyen, Kim T., Flores, Nikki J., Estey, Elihu, Gattermann, Norbert, Armstrong, Scott, Look, A. Thomas, Griffin, James D., Bernard, Olivier A., Heinrich, Michael C., Gilliland, D. Gary, Druker, Brian, Deininger, Michael W.N.

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Challenges and approaches to implementing master/basket trials in oncology von Burd, Amy, Schilsky, Richard L., Byrd, John C., Levine, Ross L., Papadimitrakopoulou, Vassiliki A., Herbst, Roy S., Redman, Mary W., Druker, Brian J., Gandara, David R.

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Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma von Clark, David J., Petralia, Francesca, Pan, Jianbo, Hu, Yingwei, Lih, Tung-Shing M., Chang, Hui-Yin, Ma, Weiping, Krek, Azra, Li, Yize, Ozbek, Umut, Wu, Yige, Chowdhury, Shrabanti, Wyczalkowski, Matthew A., Schnaubelt, Michael, Avtonomov, Dmitry M., Kalayci, Selim, Ma, Shiyong, Ruggles, Kelly, Gümüş, Zeynep H., Kawaler, Emily, Edwards, Nathan, Chen, Xi Steven, Antczak, Andrzej, Omelchenko, Tatiana, Kinsinger, Christopher R., Thiagarajan, Mathangi, Mesri, Mehdi, Robles, Ana I., Qian, Jiang, Fenyö, David, Zhang, Bing, Zhang, Zhen, Cieslik, Marcin, Chan, Daniel W., Nesvizhskii, Alexey I., Hashimi, Abdul Samad, Charamut, Alyssa, Druker, Brian J., Tognon, Cristina, Mani, D.R., Rohrer, Daniel C., Tansil, Darlene, Chesla, David, Heiman, David, Wheeler, David, Chan, Doug, Demir, Emek, Modugno, Francesmary, Getz, Gaddy, Wilson, George D., Liu, Hongwei, Zhou, Hua, Day, Jacob, Suh, James, Whiteaker, Jeffrey R., Eschbacher, Jennifer, Chen, Jin, Ketchum, Karen A., Rodland, Karin D., Krug, Karsten, Holloway, Kimberly, Sokoll, Lori J., Cornwell, MacIntosh, Loriaux, Marc, Anderson, Matthew, Ellis, Matthew J., Dyer, Maureen, Burke, Meghan C., Borucki, Melissa, Gillette, Michael A., Birrer, Michael J., Smith, Michael, Khan, Munziba, Roche, Nancy, Edwards, Nathan J., Vatanian, Negin, Tignor, Nicole, Grady, Pamela, Piehowski, Paul, McGarvey, Peter B., Hariharan, Pushpa, Gao, Qingsong, Thangudu, Ratna R., Montgomery, Rebecca, Bremner, Ross, Liu, Ruiyang, Hong, Runyu, Payne, Samuel H., Patel, Shalin, Satpathy, Shankha, Davies, Sherri R., Patil, Snehal, Carter, Sonya, Gabriel, Stacey, Thomas, Stefani N., Carr, Steven A., Skelly, Tara, Borate, Uma, Maruvka, Yosef, Li, Zhi

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A Randomized Phase 2 Trial of 28-Day (Arm A) Versus 14-Day (Arm B) Schedule of Venetoclax + Azacitidine in Newly Diagnosed Acute Myeloid Leukemia Patients ≥ 60 Years von Borate, Uma M., Huang, Ying, Johnson, Mary F., Zeidner, Joshua F., Swords, Ronan T., Koenig, Kristin L, Stein, Eytan M., Baer, Maria R., Stock, Wendy, Madanat, Yazan F., Olin, Rebecca, Blum, William, Schiller, Gary J., Lin, Tara L, Redner, Robert L., Curran, Emily K, Heerema, Nyla A., Martycz, Molly, Rosenberg, Leonard, Marcus, Sonja Gullen, Chen, Timothy, Stefanos, Mona, Levine, Ross L, Druker, Brian J., Yocum, Ashley Owen, Burd, Amy, Mims, Alice, Byrd, John C.

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A phase 1b/2 study of TP-0903 and decitabine targeting mutant TP53 and/or complex karyotype in patients with untreated acute myeloid leukemia ≥ age 60 years: Phase 1b interim resul... von Mims, Alice S., Huang, Ying, Eisenmann, Eric, Buelow, Daelynn, Swords, Ronan T., Foster, Matthew Charles, Lin, Tara L., Baer, Maria R., Kovacsovics, Tibor, Al-Mansour, Zeina, Stefanos, Mona, Druggan, Franchesca, Chen, Timothy, Yocum, Ashley, Borate, Uma, Druker, Brian J., Burd, Amy, Levine, Ross L., Baker, Sharyn D., Byrd, John C.

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A study to assess the efficacy of enasidenib and risk-adapted addition of azacitidine in newly diagnosed IDH2-mutant AML von Cai, Sheng F., Huang, Ying, Lance, Jennie R., Mao, Charlene, Dunbar, Andrew J., McNulty, Samantha N., Druley, Todd, Li, Yan, Baer, Maria R., Stock, Wendy, Kovacsovics, Tibor, Blum, William G., Schiller, Gary J., Olin, Rebecca L., Foran, James M., Litzow, Mark, Lin, Tara, Patel, Prapti, Foster, Matthew C., Boyiadzis, Michael, Collins, Robert H., Chervin, Jordan, Shoben, Abigail, Vergilio, Jo-Anne, Heerema, Nyla A., Rosenberg, Leonard, Chen, Timothy L., Yocum, Ashley O., Druggan, Franchesca, Marcus, Sonja, Stefanos, Mona, Druker, Brian J., Mims, Alice S., Borate, Uma, Burd, Amy, Byrd, John C., Levine, Ross L., Stein, Eytan M.

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Genomic Characterization of Newly Diagnosed Acute Myeloid Leukemia in Patients Age 60 Years and Older; A Report from the Beat AML Master Trial von Hoff, Fieke W, Huang, Ying, Welkie, Rina Li, Swords, Ronan T., Traer, Elie, Stein, Eytan M., Lin, Tara L, Patel, Prapti A., Collins, Robert H., Baer, Maria R., Duong, Vu H., Blum, William, Arellano, Martha, Stock, Wendy, Odenike, Olatoyosi, Redner, Robert L., Kovacsovics, Tibor J., Deininger, Michael W., Zeidner, Joshua F., Olin, Rebecca, Smith, Catherine C., Foran, James M., Schiller, Gary J., Curran, Emily K, Koenig, Kristin L, Heerema, Nyla A., Chen, Timothy, Martycz, Molly, Stefanos, Mona, Marcus, Sonja Gullen, Rosenberg, Leonard, Druker, Brian J., Levine, Ross L, Burd, Amy, Yocum, Ashley Owen, Borate, Uma M., Mims, Alice, Byrd, John C., Madanat, Yazan F.

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Beat AML S8 Group 2: Gilteritinib (GILT) in Combination with Decitabine (DEC) and Venetoclax (VEN) in Untreated FLT3 Mutated Acute Myeloid Leukemia (AML) Patients Age ≥60 with High... von Liu, Qiuying (Selina), Welkie, Rina Li, Huang, Ying, Swords, Ronan T., Lin, Tara L, Koenig, Kristin L, Madanat, Yazan F., Patel, Prapti A., Collins, Robert H., Blum, William, Arellano, Martha, Baer, Maria R., Stock, Wendy, Kovacsovics, Tibor J., Olin, Rebecca, Curran, Emily K, Stein, Eytan M., Schiller, Gary J., Zeidner, Joshua F., Redner, Robert L., Heerema, Nyla A., Martycz, Molly, Rosenberg, Leonard, Marcus, Sonja Gullen, Chen, Timothy, Stefanos, Mona, Levine, Ross L, Druker, Brian J., Yocum, Ashley Owen, Burd, Amy, Mims, Alice, Borate, Uma M., Byrd, John C., Traer, Elie

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Influence of Pre-Treatment Features and Therapy Choice By Physicians on Overall Survival in Older Adults with Acute Myeloid Leukemia: A Report from the Beat AML Master Trial von Borate, Uma M., Huang, Ying, Welkie, Rina Li, Swords, Ronan T., Traer, Elie, Stein, Eytan M., Lin, Tara L, Madanat, Yazan F., Patel, Prapti A., Collins, Robert H., Baer, Maria R., Duong, Vu H., Blum, William, Arellano, Martha, Stock, Wendy, Odenike, Olatoyosi, Redner, Robert L., Kovacsovics, Tibor J., Deininger, Michael W., Zeidner, Joshua F., Olin, Rebecca, Smith, Catherine C., Foran, James M., Schiller, Gary J., Curran, Emily K, Koenig, Kristin L, Heerema, Nyla A., Chen, Timothy, Martycz, Molly, Stefanos, Mona, Marcus, Sonja Gullen, Rosenberg, Leonard, Druker, Brian J., Levine, Ross L, Burd, Amy, Yocum, Ashley Owen, Mims, Alice, Byrd, John C.

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A Phase 1b Dose Escalation and Expansion Study of SNDX-5613, Azacitidine (AZA) and Venetoclax (VEN) in Newly Diagnosed, Patients ≥ 60 Years with Untreated NPM1-Mutated/ FLT3-Wild T... von Zeidner, Joshua F., Foster, Matthew C., Johnson, Mary, Huang, Ying, Swords, Ronan T., Stein, Eytan, Foran, James M., Baer, Maria R., Stock, Wendy, Madanat, Yazan F., Kovacsovics, Tibor, Olin, Rebecca L., Blum, William G., Schiller, Gary J., Lin, Tara L., Redner, Robert L., Al-Mansour, Zeina, Curran, Emily K, Heerema, Nyla A., Martycz, Molly, Rosenberg, Leonard, Marcus, Sonja, Yocum, Ashley O., Chen, Timothy, Stefanos, Mona, Druggan, Franchesca, Burd, Amy, Levine, Ross L., Druker, Brian J., Borate, Uma, Byrd, John C., Mims, Alice S.

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