Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin von Fleishman, Sarel J., Whitehead, Timothy A., Ekiert, Damian C., Dreyfus, Cyrille, Corn, Jacob E., Strauch, Eva-Maria, Wilson, Ian A., Baker, David

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New world bats harbor diverse influenza A viruses von Tong, Suxiang, Zhu, Xueyong, Li, Yan, Shi, Mang, Zhang, Jing, Bourgeois, Melissa, Yang, Hua, Chen, Xianfeng, Recuenco, Sergio, Gomez, Jorge, Chen, Li-Mei, Johnson, Adam, Tao, Ying, Dreyfus, Cyrille, Yu, Wenli, McBride, Ryan, Carney, Paul J, Gilbert, Amy T, Chang, Jessie, Guo, Zhu, Davis, Charles T, Paulson, James C, Stevens, James, Rupprecht, Charles E, Holmes, Edward C, Wilson, Ian A, Donis, Ruben O

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Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing von Whitehead, Timothy A, Chevalier, Aaron, Song, Yifan, Dreyfus, Cyrille, Fleishman, Sarel J, De Mattos, Cecilia, Myers, Chris A, Kamisetty, Hetunandan, Blair, Patrick, Wilson, Ian A, Baker, David

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Structure of a Classical Broadly Neutralizing Stem Antibody in Complex with a Pandemic H2 Influenza Virus Hemagglutinin von Dreyfus, Cyrille, Ekiert, Damian C, Wilson, Ian A

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Highly Conserved Protective Epitopes on Influenza B Viruses von Dreyfus, Cyrille, Laursen, Nick S., Kwaks, Ted, Zuijdgeest, David, Khayat, Reza, Ekiert, Damian C., Lee, Jeong Hyun, Metlagel, Zoltan, Bujny, Miriam V., Jongeneelen, Mandy, van der Vlugt, Remko, Lamrani, Mohammed, Korse, Hans J. W. M., Geelen, Eric, Sahin, Özcan, Sieuwerts, Martijn, Brakenhoff, Just P. J., Vogels, Ronald, Li, Olive T. W., Poon, Leo L. M., Peiris, Malik, Koudstaal, Wouter, Ward, Andrew B., Wilson, Ian A., Goudsmit, Jaap, Friesen, Robert H. E.

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Alternative recognition of the conserved stem epitope in influenza A virus hemagglutinin by a VH3-30-encoded heterosubtypic antibody von Wyrzucki, Arkadiusz, Dreyfus, Cyrille, Kohler, Ines, Steck, Marco, Wilson, Ian A, Hangartner, Lars

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A Novel Online Four-Dimensional SEC×SEC-IM×MS Methodology for Characterization of Monoclonal Antibody Size Variants von Ehkirch, Anthony, Goyon, Alexandre, Hernandez-Alba, Oscar, Rouviere, Florent, D’Atri, Valentina, Dreyfus, Cyrille, Haeuw, Jean-François, Diemer, Hélène, Beck, Alain, Heinisch, Sabine, Guillarme, Davy, Cianferani, Sarah

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Efficacy of the Antibody-Drug Conjugate W0101 in Preclinical Models of IGF-1 Receptor Overexpressing Solid Tumors von Akla, Barbara, Broussas, Matthieu, Loukili, Noureddine, Robert, Alain, Beau-Larvor, Charlotte, Malissard, Martine, Boute, Nicolas, Champion, Thierry, Haeuw, Jean-Francois, Beck, Alain, Perez, Michel, Dreyfus, Cyrille, Pavlyuk, Mariya, Chetaille, Eric, Corvaia, Nathalie

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Integrated Preclinical Data Analysis of ISB 2001 Enables Optimal Starting Dose Selection for a First-in-Class Trispecific T Cell Engager Phase1 Study in Multiple Myeloma von Drake, Adam, Pihlgren, Maria, Menon, Vinu, Pais, Daniela, Carretero-Iglesia, Laura, Berret, Jeremy, Hall, Olivia, Macoin, Julie, Gruber, Isabelle, Stainnack, Elodie, Estoppey, Carole, Dreyfus, Cyrille, Gudi, Girish, Matsuura, Tomomi, van der Graft, Piet H, Dyson, Michael, Konto, Cyril, Pacaud, Lida, Srivastava, Ankita, Zhukovsky, Eugene, Perro, Mario

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ISB 2001, a First-in-Class Trispecific BCMA and CD38 T Cell Engager Designed to Overcome Mechanisms of Escape from Treatments for Multiple Myeloma By Targeting Two Antigens von Pihlgren, Maria, Hall, Olivia, Carretero, Laura, Estoppey, Carole, Drake, Adam, Pais, Daniela, Loyau, Jeremy, Berret, Jeremy, Gruber, Isabelle, Suere, Perrine, Schnorhk, Vincent, Nallet, Emilie, Pouleau, Blandine, Chimen, Myriam, Macoin, Julie, Stainnack, Elodie, Monney, Thierry, Delachat, Aurore, Dreyfus, Cyrille, Matthes, Thomas, Konto, Cyril, Dyson, Michael, Blein, Stanislas, Mbow, Lamine, Wood, Rebecca, Srivastava, Ankita, Zhukovsky, Eugene, Perro, Mario

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Abstract 4054: Development of a new site-specific sulfomaleimide rebridging platform for the generation of homogeneous, stable, potent and safe antibody drug conjugates von Haeuw, Jean-Francois, Marion, Frederic, Dreyfus, Cyrille, Akla, Barbara, Zanna, Laurence, Janin, Marie-Claire, Beau-Larvor, Charlotte, Millet, Marion, Farrie, Martine, Batton, Alain, Thuilliez, Celine, Beck, Alain, Cianferani, Sarah, Clerc, Thierry, Maillos, Philippe, Corvaia, Nathalie

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Abstract 815: New approach for old target: W0101 antibody drug conjugate effectively inhibits tumor growth in preclinical models of IGF-1R overexpressing solid tumors von Akla, Barbara, Loukili, Noureddine, Robert, Alain, Beau-Larvor, Charlotte, Malissard, Martine, Haeuw, Jean-Francois, Beck, Alain, Perez, Michel, Dreyfus, Cyrille, Pavlyuk, Mariya, Chetaille, Eric, Corvaia, Nathalie

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Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a V H 3-30-Encoded Heterosubtypic Antibody von Wyrzucki, Arkadiusz, Dreyfus, Cyrille, Kohler, Ines, Steck, Marco, Wilson, Ian A., Hangartner, Lars

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Vers un vaccin universel contre la grippe ? von Dreyfus, Cyrille

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Towards a universal vaccine against flu? von Dreyfus, Cyrille

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ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells von Carretero-Iglesia, Laura, Hall, Olivia J., Berret, Jérémy, Pais, Daniela, Estoppey, Carole, Chimen, Myriam, Monney, Thierry, Loyau, Jeremy, Dreyfus, Cyrille, Macoin, Julie, Perez, Cynthia, Menon, Vinu, Gruber, Isabelle, Laurendon, Amélie, Caro, Lydia N., Gudi, Girish S., Matsuura, Tomomi, van der Graaf, Piet H., Blein, Stanislas, Mbow, M. Lamine, Croasdale-Wood, Rebecca, Srivastava, Ankita, Dyson, Michael R., Matthes, Thomas, Kaya, Zeynep, Edwards, Claire M., Edwards, James R., Maiga, Sophie, Pellat-Deceunynck, Catherine, Touzeau, Cyrille, Moreau, Philippe, Konto, Cyril, Drake, Adam, Zhukovsky, Eugene A., Perro, Mario, Pihlgren, Maria

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Abstract 2970: Overcoming mechanisms of escape from treatments for multiple myeloma with ISB 2001, a potential first-in-class trispecific BCMA and CD38 targeted T cell engager von Pihlgren, Maria, Carretero, Laura, Berret, Jeremy, Hall, Olivia, Estoppey, Carole, Drake, Adam, Pais, Daniela, Macoin, Julie, Chimen, Myriam, Suere, Perrine, Nallet, Emily, Pouleau, Blandine, Stainnack, Elodie, Loyau, Jeremy, Monney, Thierry, Delachat, Aurore, Dreyfus, Cyrille, Blein, Stan, Kaya, Zeynep, Matthes, Thomas, Croasdale-wood, Rebecca, Edwards, James, Edwards, Claire, Mbow, Lamine, Dyson, Michael, Konto, Cyril, Srivastava, Ankita, Zhukovshy, Eugene, Perro, Mario

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New World Bats Harbor Diverse Influenza A Viruses: e1003657 von Tong, Suxiang, Zhu, Xueyong, Li, Yan, Shi, Mang, Zhang, Jing, Bourgeois, Melissa, Yang, Hua, Chen, Xianfeng, Recuenco, Sergio, Gomez, Jorge, Chen, Li-Mei, Johnson, Adam, Tao, Ying, Dreyfus, Cyrille, Yu, Wenli, McBride, Ryan, Carney, Paul J, Gilbert, Amy T, Chang, Jessie, Guo, Zhu, Davis, Charles T, Paulson, James C, Stevens, James, Rupprecht, Charles E, Holmes, Edward C, Wilson, Ian A, Donis, Ruben O

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SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES von MARION, Frédéric, HAEUW, Jean-François, DREYFUS, Cyrille, PEREZ, Michel

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SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES von MARION, Frédéric, HAEUW, Jean-François, DREYFUS, Cyrille, PEREZ, Michel

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