Drug Absorption Interactions Between Oral Targeted Anticancer Agents and PPIs: Is pH-Dependent Solubility the Achilles Heel of Targeted Therapy? von Budha, N R, Frymoyer, A, Smelick, G S, Jin, J Y, Yago, M R, Dresser, M J, Holden, S N, Benet, L Z, Ware, J A

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Purine metabolism regulates DNA repair and therapy resistance in glioblastoma von Zhou, Weihua, Yao, Yangyang, Scott, Andrew J., Wilder-Romans, Kari, Dresser, Joseph J., Werner, Christian K., Sun, Hanshi, Pratt, Drew, Sajjakulnukit, Peter, Zhao, Shuang G., Davis, Mary, Nelson, Barbara S., Halbrook, Christopher J., Zhang, Li, Gatto, Francesco, Umemura, Yoshie, Walker, Angela K., Kachman, Maureen, Sarkaria, Jann N., Xiong, Jianping, Morgan, Meredith A., Rehemtualla, Alnawaz, Castro, Maria G., Lowenstein, Pedro, Chandrasekaran, Sriram, Lawrence, Theodore S., Lyssiotis, Costas A., Wahl, Daniel R.

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Prevalence of Acid-Reducing Agents (ARA) in Cancer Populations and ARA Drug–Drug Interaction Potential for Molecular Targeted Agents in Clinical Development von Smelick, Gillian S, Heffron, Timothy P, Chu, Laura, Dean, Brian, West, David A, DuVall, Scott L, Lum, Bert L, Budha, Nageshwar, Holden, Scott N, Benet, Leslie Z, Frymoyer, Adam, Dresser, Mark J, Ware, Joseph A

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A Guide to Rational Dosing of Monoclonal Antibodies von Bai, Shuang, Jorga, Karin, Xin, Yan, Jin, Denise, Zheng, Yanan, Damico-Beyer, Lisa A., Gupta, Manish, Tang, Meina, Allison, David E., Lu, Dan, Zhang, Yi, Joshi, Amita, Dresser, Mark J.

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Considerations on spatial crop load mapping von Taylor, J.A., Dresser, J.L., Hickey, C.C., Nuske, S.T., Bates, T.R.

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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans von Takahashi, Ryan H, Choo, Edna F, Ma, Shuguang, Wong, Susan, Halladay, Jason, Deng, Yuzhong, Rooney, Isabelle, Gates, Mary, Hop, Cornelis E C A, Khojasteh, S Cyrus, Dresser, Mark J, Musib, Luna

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Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters von Dresser, Mark J., Leabman, Maya Kaushal, Giacomini, Kathleen M.

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Inhibiting Isocitrate Dehydrogenase 1-Mediated Reductive Biosynthesis to Augment Glioblastoma Therapy von Wahl, D.R, Dresser, J, Davis, M.A, Zhao, S.G, Morgan, M.A, Lyssiotis, C, Feng, F.Y, Lawrence, T.S

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Cloning and Functional Expression of a Human Liver Organic Cation Transporter von Zhang, L, Dresser, M J, Gray, A T, Yost, S C, Terashita, S, Giacomini, K M

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Single- and Multiple-Dose Pharmacokinetics of Dapoxetine Hydrochloride, a Novel Agent for the Treatment of Premature Ejaculation von Modi, Nishit B., Dresser, Mark J., Simon, Mary, Lin, Denise, Desai, Dhaval, Gupta, Suneel

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Impact of Food and the Proton Pump Inhibitor Rabeprazole on the Pharmacokinetics of GDC-0941 in Healthy Volunteers: Bench to Bedside Investigation of pH-Dependent Solubility von Ware, Joseph A, Dalziel, Gena, Jin, Jin Y, Pellett, Jackson D, Smelick, Gillian S, West, David A, Salphati, Laurent, Ding, Xiao, Sutton, Rebecca, Fridyland, Jane, Dresser, Mark J, Morrisson, Glenn, Holden, Scott N

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Dapoxetine, a novel treatment for premature ejaculation, does not have pharmacokinetic interactions with phosphodiesterase-5 inhibitors von DRESSER, M. J, DESAI, D, GIDWANI, S, SEFTEL, A. D, MODI, N. B

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Best practices for the use of itraconazole as a replacement for ketoconazole in drug-drug interaction studies von Liu, Lichuan, Bello, Akintunde, Dresser, Mark J., Heald, Donald, Komjathy, Steven Ferenc, O'Mara, Edward, Rogge, Mark, Stoch, S. Aubrey, Robertson, Sarah M.

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Arginine 454 and Lysine 370 Are Essential for the Anion Specificity of the Organic Anion Transporter, rOAT3 von Feng, Bo, Dresser, Mark J, Shu, Yan, Johns, Susan Jean, Giacomini, Kathleen M

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TEM annealing study of normal grain growth in silver thin films von Dannenberg, Rand, Stach, Eric, Groza, Joanna R, Dresser, Brian J

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In-situ TEM observations of abnormal grain growth, coarsening, and substrate de-wetting in nanocrystalline Ag thin films von Dannenberg, Rand, Stach, E.A., Groza, J.R., Dresser, B.J.

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A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer von Cheeti, Sravanthi, Budha, Nageshwar R., Rajan, Sharmila, Dresser, Mark J., Jin, Jin Y.

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Absolute Bioavailability and Effect of Formulation Change, Food, or Elevated pH with Rabeprazole on Cobimetinib Absorption in Healthy Subjects von Musib, Luna, Choo, Edna, Deng, Yuzhong, Eppler, Steve, Rooney, Isabelle, Chan, Iris T, Dresser, Mark J

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Na+-dependent purine nucleoside transporter from human kidney: cloning and functional characterization von Wang, Juan, Su, Sheng-Fang, Dresser, Mark J, Schaner, Marci E, Washington, Carla B, Giacomini, Kathleen M

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A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor... von Malhi, Vikram, Colburn, Dawn, Williams, Sarah J., Hop, Cornelis E. C. A., Dresser, Mark J., Chandra, Priya, Graham, Richard A.

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