A stepwise approach for effective management of chronic pain in autosomal-dominant polycystic kidney disease von Casteleijn, Niek F, Visser, Folkert W, Drenth, Joost P H, Gevers, Tom J G, Groen, Gerbrand J, Hogan, Marie C, Gansevoort, Ron T

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Decreased tacrolimus plasma concentrations during HCV therapy: a drug–drug interaction or is there an alternative explanation? von Smolders, E.J, Pape, S, de Kanter, C.T.M.M, van den Berg, A.P, Drenth, J.P.H, Burger, D.M

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GANAB mutations: a possible lead to a common hepatic cystogenesis pathway in autosomal dominant polycystic kidney and liver disease? von Van De Laarschot, L.F.M, te Morsche, R.H, Drenth, J.P.H

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Durable response in the markers of cholestasis through 5 years of open-label extension study of obeticholic acid in primary biliary cholangitis von Nevens, F., Shiffman, M.L., Drenth, J.P.H., Bowlus, C.L., Vargas, V., Andreone, P., van Erpecum, K., Floreani, A., Liberman, A., Pencek, R., Malecha, E. Smoot, MacConell, L., Trauner, M.

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P1264 CLINICAL HETEROGENEITY IN POLYCYSTIC LIVER DISEASE FAMILIES von Cnossen, W.R, Salomon, J, te Morsche, R.H.M, Drenth, J.P.H

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32 GENOME WIDE ANALYSIS IDENTIFIES MITOTIC RECOMBINATION AS CAUSE OF SOMATIC LOSS OF HETEROZYGOSITY IN CYSTS FROM POLYCYSTIC LIVER DISEASE PATIENTS von Janssen, M, Pfundt, R, Drenth, J.P.H

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The Pan-Genotypic Costs-Effectiveness Of Sofosbuvir in Hepatitis C Virus von Novak, A, Drenth, J.P.H, de Knegt, R.J

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Costs Per Successfully Treated Patient with Sofosbuvir in GT1 HCV von Novak, A, Drenth, J.P.H, de Knegt, R.J

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1394 COPY NUMBER ASSAY IN POLYCYSTIC LIVER DISEASE BY MULTIPLEX LIGATION-DEPENDENT PROBE AMPLIFICATION von Maurits, J.S.F, Cnossen, W.R, Waanders, E, te Morsche, R.H.M, Drenth, J.P.H

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1386 EVEROLIMUS DOES NOT FURTHER REDUCE POLYCYSTIC LIVER VOLUME WHEN ADDED TO LONG ACTING OCTREOTIDE: RESULTS FROM A RANDOMIZED CONTROLLED TRIAL IN POLYCYSTIC LIVER DISEASE PATIENT... von Chrispijn, M, Gevers, T.J.G, Hol, J.C, Monshouwer, R, Dekker, H.M, Drenth, J.P.H

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1386 LOW PREVALENCE OF CARDIAC VALVE ABNORMALITIES IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC LIVER DISEASE von Gevers, T.J.G, de Koning, D.B, van Dijk, A.P, Drenth, J.P.H

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346 SOMATIC INACTIVATION IN POLYCYSTIC LIVER SEC63 GERMLINE CARRIERS OCCURS THROUGH LOSS OF HETEROZYGOSITY von Janssen, M.J, Salomon, J, te Morsche, R.H.M, Drenth, J.P.H

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Laparoscopy in cholecysto-choledocholithiasis von van Dijk, A.H., MD, Lamberts, M., MD, van Laarhoven, C.J.H.M., MD, PhD, Drenth, J.P.H., MD, PhD, Boermeester, M.A., MD, PhD, de Reuver, P.R., MD, PhD

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P1250 CHARACTERIZATION AND MANAGEMENT OF HEPATIC AND RENAL CYST INFECTION PATIENTS – A MULTICENTER RETROSPECTIVE STUDY von Lantinga, M.A, Gevers, T.J.G, de Sévaux, R.G.L, Oyen, W.J.G, de Fijter, J.W, Soonawala, D, Salih, M, Meijer, E, Gansevoort, R.T, Drenth, J.P.H

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P1211 HIGH DOSE RIBAVIRIN INFLUENCES EARLY VIRAL KINETICS AND IMPROVES SVR RATES IN CHRONIC HCV PATIENTS WHO ADHERE TO THERAPY (VIRID STUDY) von Koning, L, Drenth, J.P.H, Roomer, R, Brouwer, J.T, Aparicio, N, Den Hollander, J.G, Baak, B.C, Honkoop, P, Klemt-Kropp, M, Janssen, H.L.A, Hansen, B.E, de Knegt, R.J

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696 LOSS OF HETEROZYGOSITY IN LIVER CYSTS OF AUTOSOMAL DOMINANT POLYCYSTIC LIVER DISEASE (PCLD) DEPENDS ON GERMLINE MUTATION OF THE PATIENT von Janssen, M.J, Woudenberg, J, te Morsche, R.H.M, Drenth, J.P.H

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O122 : Clinical impact of five large-scale screening projects for chronic hepatitis B and C in Chinese migrants in The Netherlands von Coenen, S, van Meer, S, Vrolijk, J.M, Richter, C, Drenth, J.P.H, Koopmans, P.P, van Soest, H, van Erpecum, K.J, Arends, J.E, Verhagen, M.A.M.T, Friederich, P, Flink, H.J, ter Borg, M.J, Veldhuijzen, I.K, Reijnders, J.G.P, Mostert, M.C, Dirksen, C.G, Schout, C, Daemen, H.P.J, Spanier, B.W.M

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P1183 : Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease von Muñoz, P, Garcia Marín, J.J, Perugorria, M.J, Urribarri, A.D, Saez, E, Uriz, M, Sarvide, S, Portu, A, Concepción, A, Rodriguez Romero, M, Monte, M.J, Santos-Laso, A, Hijona, E, Jimenez-Agüero, R, Marzioni, M, Beuers, U, Masyuk, T.V, LaRusso, N.F, Prieto, J, Drenth, J.P.H, Bujanda, L, Bañales, J.M

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1387 IDENTIFICATION OF A NOVEL GENE ASSOCIATED WITH POLYCYSTIC LIVER AND KIDNEY DISEASES von Cnossen, W.R, te Morsche, R.H.M, Hoischen, A, Gilissen, C, Chrispijn, M, Venselaar, H, Mehdi, S, Bergmann, C, Veltman, J.A, Drenth, J.P.H

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P390 IMPACT IN DAILY PRACTICE OF THE CONCEPT OF TREATMENT RESPONSE IN PRIMARY BILIARY CIRRHOSIS. A NATIONAL COHORT STUDY von Leeman, M, Lammers, W.J, Ponsioen, C.Y, Boonstra, K, van Erpecum, K.J, Wolfhagen, F.H.J, Kuyvenhoven, J.P, Vrolijk, J.M, Drenth, J.P.H, Witteman, E.M, van Nieuwkerk, C.M.J, van der Spek, B.W, Witteman, B.J.M, Erkelens, G.W, Verhagen, M.A.M.T, van Tuyl, S.A.C, Poen, A.C, Brouwer, J.T, ter Borg, F, Koek, G.H, van Ditzhuijsen, T.J.M, Hansen, B.E, van Buuren, H.R

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