Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus von Downes, Damien J., Cross, Amy R., Hua, Peng, Roberts, Nigel, Schwessinger, Ron, Cutler, Antony J., Munis, Altar M., Brown, Jill, Mielczarek, Olga, de Andrea, Carlos E., Melero, Ignacio, Gill, Deborah R., Hyde, Stephen C., Knight, Julian C., Todd, John A., Sansom, Stephen N., Issa, Fadi, Davies, James O. J., Hughes, Jim R.

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Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo von Hanssen, Lars L. P., Kassouf, Mira T., Oudelaar, A. Marieke, Biggs, Daniel, Preece, Chris, Downes, Damien J., Gosden, Matthew, Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline A., Hughes, Jim R., Davies, Benjamin, Higgs, Douglas R.

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DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation von Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.

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The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin von Truch, Julia, Downes, Damien J., Scott, Caroline, Gür, E. Ravza, Telenius, Jelena M., Repapi, Emmanouela, Schwessinger, Ron, Gosden, Matthew, Brown, Jill M., Taylor, Stephen, Cheong, Pak Leng, Hughes, Jim R., Higgs, Douglas R., Gibbons, Richard J.

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Comparing the two leading erythroid lines BEL-A and HUDEP-2 von Daniels, Deborah E., Downes, Damien J., Ferrer-Vicens, Ivan, Ferguson, Daniel C. J., Singleton, Belinda K., Wilson, Marieangela C., Trakarnsanga, Kongtana, Kurita, Ryo, Nakamura, Yukio, Anstee, David J., Frayne, Jan

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A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker von Bozhilov, Yavor K., Downes, Damien J., Telenius, Jelena, Marieke Oudelaar, A., Olivier, Emmanuel N., Mountford, Joanne C., Hughes, Jim R., Gibbons, Richard J., Higgs, Douglas R.

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High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale von Downes, Damien J., Beagrie, Robert A., Gosden, Matthew E., Telenius, Jelena, Carpenter, Stephanie J., Nussbaum, Lea, De Ornellas, Sara, Sergeant, Martin, Eijsbouts, Chris Q., Schwessinger, Ron, Kerry, Jon, Roberts, Nigel, Shivalingam, Arun, El-Sagheer, Afaf, Oudelaar, A. Marieke, Brown, Tom, Buckle, Veronica J., Davies, James O. J., Hughes, Jim R.

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Erratum to: Comparing the two leading erythroid lines BEL-A and HUDEP-2 von Daniels, Deborah E, Downes, Damien J, Ferrer-Vicens, Ivan, Ferguson, Daniel C J, Singleton, Belinda K, Wilson, Marieangela C, Trakarnsanga, Kongtana, Kurita, Ryo, Nakamura, Yukio, Anstee, David J, Frayne, Jan

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Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development von Owens, Dominic D. G., Anselmi, Giorgio, Oudelaar, A. Marieke, Downes, Damien J., Cavallo, Alessandro, Harman, Joe R., Schwessinger, Ron, Bucakci, Akin, Greder, Lucas, de Ornellas, Sara, Jeziorska, Danuta, Telenius, Jelena, Hughes, Jim R., de Bruijn, Marella F. T. R.

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Reactivation of a developmentally silenced embryonic globin gene von King, Andrew J., Songdej, Duantida, Downes, Damien J., Beagrie, Robert A., Liu, Siyu, Buckley, Megan, Hua, Peng, Suciu, Maria C., Marieke Oudelaar, A., Hanssen, Lars L. P., Jeziorska, Danuta, Roberts, Nigel, Carpenter, Stephanie J., Francis, Helena, Telenius, Jelena, Olijnik, Aude-Anais, Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline, Eglinton, Jennifer, Kassouf, Mira T., Orkin, Stuart H., Pennacchio, Len A., Davies, James O. J., Hughes, Jim R., Higgs, Douglas R., Babbs, Christian

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Recapitulation of erythropoiesis in congenital dyserythropoietic anemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities von Scott, Caroline, Downes, Damien J., Brown, Jill M., Beagrie, Robert, Olijnik, Aude-Anais, Gosden, Matthew, Schwessinger, Ron, Fisher, Christopher A., Rose, Anna, Ferguson, David J. P., Johnson, Errin, Hill, Quentin A., Okoli, Steven, Renella, Raffaele, Ryan, Kate, Brand, Marjorie, Hughes, Jim, Roy, Noemi B. A., Higgs, Douglas R., Babbs, Christian, Buckle, Veronica J.

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Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans von Steyer, Joel T., Downes, Damien J., Hunter, Cameron C., Migeon, Pierre A., Todd, Richard B.

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Defining genome architecture at base-pair resolution von Hua, Peng, Badat, Mohsin, Hanssen, Lars L. P., Hentges, Lance D., Crump, Nicholas, Downes, Damien J., Jeziorska, Danuta M., Oudelaar, A. Marieke, Schwessinger, Ron, Taylor, Stephen, Milne, Thomas A., Hughes, Jim R., Higgs, Doug R., Davies, James O. J.

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Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types von Miar, Ana, Arnaiz, Esther, Bridges, Esther, Beedie, Shaunna, Cribbs, Adam P., Downes, Damien J., Beagrie, Robert A., Rehwinkel, Jan, Harris, Adrian L.

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Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells von Torres, Jason M, Sun, Han, Nylander, Vibe, Downes, Damien J, van de Bunt, Martijn, McCarthy, Mark I, Hughes, Jim R, Gloyn, Anna L

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Natural and Experimental Rewiring of Gene Regulatory Regions von Downes, Damien J, Hughes, Jim R

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Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains von Oudelaar, A. Marieke, Davies, James O. J., Hanssen, Lars L. P., Telenius, Jelena M., Schwessinger, Ron, Liu, Yu, Brown, Jill M., Downes, Damien J., Chiariello, Andrea M., Bianco, Simona, Nicodemi, Mario, Buckle, Veronica J., Dekker, Job, Higgs, Douglas R., Hughes, Jim R.

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Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis von Gillespie, Mark A., Palii, Carmen G., Sanchez-Taltavull, Daniel, Shannon, Paul, Longabaugh, William J.R., Downes, Damien J., Sivaraman, Karthi, Espinoza, Herbert M., Hughes, Jim R., Price, Nathan D., Perkins, Theodore J., Ranish, Jeffrey A., Brand, Marjorie

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Multi Locus View: an extensible web-based tool for the analysis of genomic data von Sergeant, Martin J., Hughes, Jim R., Hentges, Lance, Lunter, Gerton, Downes, Damien J., Taylor, Stephen

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LanceOtron: a deep learning peak caller for genome sequencing experiments von Hentges, Lance D, Sergeant, Martin J, Cole, Christopher B, Downes, Damien J, Hughes, Jim R, Taylor, Stephen

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