CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer von Zhang, Hua, Christensen, Camilla L., Dries, Ruben, Oser, Matthew G., Deng, Jiehui, Diskin, Brian, Li, Fei, Pan, Yuanwang, Zhang, Xuzhu, Yin, Yandong, Papadopoulos, Eleni, Pyon, Val, Thakurdin, Cassandra, Kwiatkowski, Nicholas, Jani, Kandarp, Rabin, Alexandra R., Castro, Dayanne M., Chen, Ting, Silver, Heather, Huang, Qingyuan, Bulatovic, Mirna, Dowling, Catríona M., Sundberg, Belen, Leggett, Alan, Ranieri, Michela, Han, Han, Li, Shuai, Yang, Annan, Labbe, Kristen E., Almonte, Christina, Sviderskiy, Vladislav O., Quinn, Max, Donaghue, Jack, Wang, Eric S., Zhang, Tinghu, He, Zhixiang, Velcheti, Vamsidhar, Hammerman, Peter S., Freeman, Gordon J., Bonneau, Richard, Kaelin, William G., Sutherland, Kate D., Kersbergen, Ariena, Aguirre, Andrew J., Yuan, Guo-Cheng, Rothenberg, Eli, Miller, George, Gray, Nathanael S., Wong, Kwok-Kin

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In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma von Li, Fei, Huang, Qingyuan, Luster, Troy A., Hu, Hai, Zhang, Hua, Ng, Wai-Lung, Khodadadi-Jamayran, Alireza, Wang, Wei, Chen, Ting, Deng, Jiehui, Ranieri, Michela, Fang, Zhaoyuan, Pyon, Val, Dowling, Catriona M., Bagdatlioglu, Ece, Almonte, Christina, Labbe, Kristen, Silver, Heather, Rabin, Alexandra R., Jani, Kandarp, Tsirigos, Aristotelis, Papagiannakopoulos, Thales, Hammerman, Peter S., Velcheti, Vamsidhar, Freeman, Gordon J., Qi, Jun, Miller, George, Wong, Kwok-Kin

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Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells von Dowling, Catríona M, Herranz Ors, Carmen, Kiely, Patrick A

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Generation of Genetically Engineered Mouse Lung Organoid Models for Squamous Cell Lung Cancers Allows for the Study of Combinatorial Immunotherapy von Hai, Josephine, Zhang, Hua, Zhou, Jin, Wu, Zhong, Chen, Ting, Papadopoulos, Eleni, Dowling, Catriona M., Pyon, Val, Pan, Yuanwang, Liu, Jie Bin, Bronson, Roderick T., Silver, Heather, Lizotte, Patrick H., Deng, Jiehui, Campbell, Joshua D., Sholl, Lynette M., Ng, Christine, Tsao, Ming-Sound, Thakurdin, Cassandra, Bass, Adam J., Wong, Kwok-Kin

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Shining a light on metabolic vulnerabilities in non-small cell lung cancer von Dowling, Catríona M., Zhang, Hua, Chonghaile, Tríona Ní, Wong, Kwok-Kin

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Extracellular matrix gene expression profiling using microfluidics for colorectal carcinoma stratification von Hayes, Christopher J., Dowling, Catriona M., Dwane, Susan, McCumiskey, Mary E., Tormey, Shona M., Anne Merrigan, B., Coffey, John C., Kiely, Patrick A., Dalton, Tara M.

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Immunotherapy through the Lens of Non-Small Cell Lung Cancer von Stanley, Robyn, Flanagan, Saoirse, Reilly, David O', Kearney, Ella, Naidoo, Jarushka, Dowling, Catríona M

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Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer von Li, Fei, Ng, Wai-Lung, Luster, Troy A., Hu, Hai, Sviderskiy, Vladislav O., Dowling, Catriona M., Hollinshead, Kate E. R., Zouitine, Paula, Zhang, Hua, Huang, Qingyuan, Ranieri, Michela, Wang, Wei, Fang, Zhaoyuan, Chen, Ting, Deng, Jiehui, Zhao, Kai, So, Hon-Cheong, Khodadadi-Jamayran, Alireza, Xu, Mousheng, Karatza, Angeliki, Pyon, Val, Li, Shuai, Pan, Yuanwang, Labbe, Kristen, Almonte, Christina, Poirier, John T., Miller, George, Possemato, Richard, Qi, Jun, Wong, Kwok-Kin

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BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer von Walsh, Louise, Haley, Kathryn E, Moran, Bruce, Mooney, Brian, Tarrant, Finbarr, Madden, Stephen F, Di Grande, Alessandra, Fan, Yue, Das, Sudipto, Rueda, Oscar M, Dowling, Catríona M, Varešlija, Damir, Chin, Suet-Feung, Linn, Sabine, Young, Leonie S, Jirström, Karin, Crown, John P, Bernards, Rene, Caldas, Carlos, Gallagher, William M, O'Connor, Darran P, Ní Chonghaile, Tríona

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Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC von Zhang, Hua, Nabel, Christopher S., Li, Dezhi, O’Connor, Ruth Í., Crosby, Caroline R., Chang, Sarah M., Hao, Yuan, Stanley, Robyn, Sahu, Soumyadip, Levin, Daniel S., Chen, Ting, Tang, Sittinon, Huang, Hsin-Yi, Meynardie, Mary, Stephens, Janaye, Sherman, Fiona, Chafitz, Alison, Costelloe, Naoise, Rodrigues, Daniel A., Fogarty, Hilda, Kiernan, Miranda G., Cronin, Fiona, Papadopoulos, Eleni, Ploszaj, Magdalena, Weerasekara, Vajira, Deng, Jiehui, Kiely, Patrick, Bardeesy, Nabeel, Vander Heiden, Matthew G., Chonghaile, Triona Ni, Dowling, Catríona M., Wong, Kwok-Kin

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Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer von Dowling, Catriona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Dussmann, Heiko, O'Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Triona Ni

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Targeting the Atf7ip-Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity von Hu, Hai, Khodadadi-Jamayran, Alireza, Dolgalev, Igor, Cho, Hyunwoo, Badri, Sana, Chiriboga, Luis A., Zeck, Briana, Gregorio, Miguel Lopez De Rodas, Dowling, Catriona M., Labbe, Kristen, Deng, Jiehui, Chen, Ting, Zhang, Hua, Zappile, Paul, Chen, Ze, Ueberheide, Beatrix, Karatza, Angeliki, Han, Han, Ranieri, Michela, Tang, Sittinon, Jour, George, Osman, Iman, Sucker, Antje, Schadendorf, Dirk, Tsirigos, Aristotelis, Schalper, Kurt A., Velcheti, Vamsidhar, Huang, Hsin-yi, Jin, Yujuan, Ji, Hongbin, Poirier, John T., Li, Fei, Wong, Kwok-Kin

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Expression of protein kinase C gamma promotes cell migration in colon cancer von Dowling, Catríona M, Hayes, Sheri L, Phelan, James J, Cathcart, Mary Clare, Finn, Stephen P, Mehigan, Brian, McCormick, Paul, Coffey, John C, O'sullivan, Jacintha, Kiely, Patrick A

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Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival von Dowling, Catríona M, Phelan, James, Callender, Julia A, Cathcart, Mary Clare, Mehigan, Brian, McCormick, Paul, Dalton, Tara, Coffey, John C, Newton, Alexandra C, O'Sullivan, Jacintha, Kiely, Patrick A

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Targeting Protein Kinase C Downstream of Growth Factor and Adhesion Signalling von Dowling, Catríona M, Kiely, Patrick A

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The importance of selecting the appropriate reference genes for quantitative real time PCR as illustrated using colon cancer cells and tissue von Dowling, Catríona M, Walsh, Dara, Coffey, John C, Kiely, Patrick A

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HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression von Cartwright, Tyrell N., Worrell, Julie C., Marchetti, Letizia, Dowling, Catríona M., Knox, Amber, Kiely, Patrick, Mann, Jelena, Mann, Derek A., Wilson, Caroline L.

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The importance of selecting the appropriate reference genes for quantitative real time PCR as illustrated using colon cancer cells and tissue [version 2; peer review: 2 approved] von Dowling, Catríona M, Walsh, Dara, Coffey, John C, Kiely, Patrick A

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Abstract 2326: A high-throughput screen identified cancer selective small molecules that kill independent of mitochondrial apoptosis von Dowling, Catriona M., Hemann, Micheal, Bradner, James, Letai, Anthony, Chonghaile, Triona Ni

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Abstract 1888: Protein kinase C beta II suppresses colorectal cancer by regulating IGF1 mediated cell survival von Dowling, Catriona M., Phelan, James, Callender, Julia A., Cathcart, Mary Clare, Mehigan, Brian, McCormick, Paul, Dalton, Tara, Coffey, John C., Newton, Alexandra C., O’Sullivan, Jacintha, Kiely, Patrick A.

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