Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology von Dourlen, P, Fernandez-Gomez, F J, Dupont, C, Grenier-Boley, B, Bellenguez, C, Obriot, H, Caillierez, R, Sottejeau, Y, Chapuis, J, Bretteville, A, Abdelfettah, F, Delay, C, Malmanche, N, Soininen, H, Hiltunen, M, Galas, M-C, Amouyel, P, Sergeant, N, Buée, L, Lambert, J-C, Dermaut, B

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Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology von Chapuis, J, Hansmannel, F, Gistelinck, M, Mounier, A, Van Cauwenberghe, C, Kolen, K V, Geller, F, Sottejeau, Y, Harold, D, Dourlen, P, Grenier-Boley, B, Kamatani, Y, Delepine, B, Demiautte, F, Zelenika, D, Zommer, N, Hamdane, M, Bellenguez, C, Dartigues, J-F, Hauw, J-J, Letronne, F, Ayral, A-M, Sleegers, K, Schellens, A, Broeck, L V, Engelborghs, S, De Deyn, P P, Vandenberghe, R, O'Donovan, M, Owen, M, Epelbaum, J, Mercken, M, Karran, E, Bantscheff, M, Drewes, G, Joberty, G, Campion, D, Octave, J-N, Berr, C, Lathrop, M, Callaerts, P, Mann, D, Williams, J, Buée, L, Dewachter, I, Van Broeckhoven, C, Amouyel, P, Moechars, D, Dermaut, B, Lambert, J-C

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Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation von Dichtel-Danjoy, M-L, Ma, D, Dourlen, P, Chatelain, G, Napoletano, F, Robin, M, Corbet, M, Levet, C, Hafsi, H, Hainaut, P, Ryoo, H D, Bourdon, J-C, Mollereau, B

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Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina von Van Den Brink, Daan M, Cubizolle, Aurélie, Chatelain, Gilles, Davoust, Nathalie, Girard, Victor, Johansen, Simone, Napoletano, Francesco, Dourlen, Pierre, Guillou, Laurent, Angebault-Prouteau, Claire, Bernoud-Hubac, Nathalie, Guichardant, Michel, Brabet, Philippe, Mollereau, Bertrand

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The peptidyl prolyl cis/trans isomerase Pin1 downregulates the Inhibitor of Apoptosis Protein Survivin von Dourlen, P., Ando, K., Hamdane, M., Begard, S., Buée, L., Galas, M.C.

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Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology von Dourlen, P, Fernandez-Gomez, FJ, Dupont, C, Grenier-Boley, B, Bellenguez, C, Obriot, H, Caillierez, R, Sottejeau, Y, Chapuis, J, Bretteville, A, Abdelfettah, F, Delay, C, Malmanche, N, Soininen, H, Hiltunen, M, Galas, M-C, Amouyel, P, Sergeant, N, Buée, L, Lambert, J-C, Dermaut, Bart

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Pin1 allows for differential Tau dephosphorylation in neuronal cells von Hamdane, Malika, Dourlen, Pierre, Bretteville, Alexis, Sambo, Anne-Véronique, Ferreira, Stéphanie, Ando, Kunie, Kerdraon, Olivier, Bégard, Séverine, Geay, Linda, Lippens, Guy, Sergeant, Nicolas, Delacourte, André, Maurage, Claude-Alain, Galas, Marie-Christine, Buée, Luc

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Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology von Chapuis, J, Hansmannel, F, Gistelinck, Marc, Mounier, A, Van Cauwenberghe, C, Kolen, K.V, Geller, F, Sottejeau, Y, Harold, D, Dourlen, P, Grenier-Boley, B, Kamatani, Y, Delepine, B, Demiautte, F, Zelenika, D, Zommer, N, Hamdane, M, Bellenguez, C, Dartigues, J.-F, Hauw, J.-J, Letronne, F, Ayral, A.-M, Sleegers, K, Schellens, Annik, Broeck, L.V, Engelborghs, S, De Deyn, P.P, Vandenberghe, R, O'Donovan, M, Owen, M, Epelbaum, J, Mercken, M, Karran, Eric, Bantscheff, M, Drewes, G, Joberty, G, Campion, D, Octave, J.-N, Berr, C, Lathrop, M, Callaerts, Patrick, Mann, D, Williams, J, Buée, L, Dewachter, I, Van Broeckhoven, C, Amouyel, P, Moechars, D, Dermaut, B, Lambert, J.-C, GERAD consortium

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P1-10 The prolyl isomerase PIN1 modulates oxydative stress-induced dephosphorylation of tau in neurons von Galas, M.C., Dourlen, P., Bégard, S., Vandesquille, M., Hamdame, M., Buée, L.

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Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism von Chapuis, J, Flaig, A, Grenier-Boley, B, Eysert, F, Pottiez, V, Deloison, G, Vandeputte, A, Ayral, A-M, Mendes, T, Desai, S, Goate, AM, Kauwe, JSK, Leroux, F, Herledan, A, Demiautte, F, Bauer, C, Checler, F, Petersen, RC, Blennow, K, Zetterberg, H, Minthon, L, Van Deerlin, VM, Lee, VM-Y, Shaw, LM, Trojanowski, JQ, Albert, M, Moghekar, A, O'Brien, R, Peskind, ER, Malmanche, N, Schellenberg, GD, Dourlen, P, Song, O-R, Cruchaga, C, Amouyel, P, Deprez, B, Brodin, P, Lambert, J-C

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C2-4 La protéine microtubulaire Tau : le ying et le yang des tauopathies von Hamdane, M., Bretteville, A., Ando, K., Dourlen, P., Schindowski, K., Kerdraon, O., Bégard, S., Schraen-Mashke, S., Caillet-Boudin, M.L., Sergeant, N., Delacourte, A., Galas, M.C., Maurage, C.A., Buée, L.

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use of MapPop1.0 for choosing a QTL mapping sample from an advanced backcross population von Birolleau-Touchard, C, Hanocq, E, Bouchez, A, Bauland, C, Dourlen, I, Seret, J. -P, Rabier, D, Hervet, S, Allienne, J. -F, Lucas, Ph, Jaminon, O, Etienne, R, Baudhuin, G, Giauffret, C

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La stérilisation volontaire en France et dans le monde von S., J.-P., Palmer, R., Dourlen-Rollier, A. M., Audebert, A., Geraud, R.

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