The genomic landscape of African populations in health and disease von Rotimi, Charles N, Bentley, Amy R, Doumatey, Ayo P, Chen, Guanjie, Shriner, Daniel, Adeyemo, Adebowale

Volltext

Gut Microbiome Profiles Are Associated With Type 2 Diabetes in Urban Africans von Doumatey, Ayo P., Adeyemo, Adebowale, Zhou, Jie, Lei, Lin, Adebamowo, Sally N., Adebamowo, Clement, Rotimi, Charles N.

Volltext

Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes von Chen, Guanjie, Shriner, Daniel, Zhang, Jianhua, Zhou, Jie, Adikaram, Poorni, Doumatey, Ayo P, Bentley, Amy R, Adeyemo, Adebowale, Rotimi, Charles N

Volltext

Lipidomics profiling and circulating triglyceride concentrations in sub-Saharan African individuals von Bentley, Amy R., Doumatey, Ayo P., Zhou, Jie, Lei, Lin, Meeks, Karlijn A. C., Heuston, Elisabeth F., Rotimi, Charles N., Adeyemo, Adebowale A.

Volltext

Genetic risk scores for cardiometabolic traits in sub-Saharan African populations von Ekoru, Kenneth, Adeyemo, Adebowale A, Chen, Guanjie, Doumatey, Ayo P, Zhou, Jie, Bentley, Amy R, Shriner, Daniel, Rotimi, Charles N

Volltext

Mendelian randomization study reveals a causal relationship between adiponectin and LDL cholesterol in Africans von Meeks, Karlijn A. C., Bentley, Amy R., Doumatey, Ayo P., Adeyemo, Adebowale A., Rotimi, Charles N.

Volltext

Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations von Szczesny, Brooke, Boorgula, Meher Preethi, Chavan, Sameer, Campbell, Monica, Johnson, Randi K., Kammers, Kai, Thompson, Emma E., Cox, Madison S., Shankar, Gautam, Cox, Corey, Morin, Andréanne, Lorizio, Wendy, Daya, Michelle, Kelada, Samir N. P., Beaty, Terri H., Doumatey, Ayo P., Cruz, Alvaro A., Watson, Harold, Naureckas, Edward T., Giles, B. Louise, Arinola, Ganiyu A., Sogaolu, Olumide, Falade, Adegoke G., Hansel, Nadia N., Yang, Ivana V., Olopade, Christopher O., Rotimi, Charles N., Landis, R. Clive, Figueiredo, Camila A., Altman, Matthew C., Kenny, Eimear, Ruczinski, Ingo, Liu, Andrew H., Ober, Carole, Taub, Margaret A., Barnes, Kathleen C., Mathias, Rasika A.

Volltext

Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensiti... von Meeks, Karlijn A C, Bentley, Amy R, Assimes, Themistocles L, Franceschini, Nora, Adeyemo, Adebowale A, Rotimi, Charles N, Doumatey, Ayo P

Volltext

Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians von Doumatey, Ayo P, Shriner, Daniel, Zhou, Jie, Lei, Lin, Chen, Guanjie, Oluwasola-Taiwo, Omolara, Nkem, Susan, Ogundeji, Adela, Adebamowo, Sally N, Bentley, Amy R, Gouveia, Mateus H, Meeks, Karlijn A C, Adebamowo, Clement A, Adeyemo, Adebowale A, Rotimi, Charles N

Volltext

Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits von Meeks, Karlijn A. C., Bentley, Amy R., Gouveia, Mateus H., Chen, Guanjie, Zhou, Jie, Lei, Lin, Adeyemo, Adebowale A., Doumatey, Ayo P., Rotimi, Charles N.

Volltext

Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome von Tekola-Ayele, Fasil, Doumatey, Ayo P., Shriner, Daniel, Bentley, Amy R., Chen, Guanjie, Zhou, Jie, Fasanmade, Olufemi, Johnson, Thomas, Oli, Johnnie, Okafor, Godfrey, Eghan, Benjami A., Agyenim-Boateng, Kofi, Adebamowo, Clement, Amoah, Albert, Acheampong, Joseph, Adeyemo, Adebowale, Rotimi, Charles N.

Volltext

Time-to-event modeling of hypertension reveals the nonexistence of true controls von Shriner, Daniel, Bentley, Amy R., Zhou, Jie, Ekoru, Kenneth, Doumatey, Ayo P., Chen, Guanjie, Adeyemo, Adebowale, Rotimi, Charles N.

Volltext

Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese von Chen, Guanjie, Zhang, Zhenjian, Adebamowo, Sally N, Liu, Guozheng, Adeyemo, Adebowale, Zhou, Yanxun, Doumatey, Ayo P, Wang, Chuntao, Zhou, Jie, Yan, Wenqiang, Shriner, Daniel, Tekola-Ayele, Fasil, Bentley, Amy R, Jiang, Congqing, Rotimi, Charles N

Volltext

Universal genome-wide association studies: Powerful joint ancestry and association testing von Shriner, Daniel, Bentley, Amy R., Gouveia, Mateus H., Heuston, Elisabeth F., Doumatey, Ayo P., Chen, Guanjie, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.

Volltext

Gene-based sequencing identifies lipid-influencing variants with ethnicity-specific effects in African Americans von Bentley, Amy R, Chen, Guanjie, Shriner, Daniel, Doumatey, Ayo P, Zhou, Jie, Huang, Hanxia, Mullikin, James C, Blakesley, Robert W, Hansen, Nancy F, Bouffard, Gerard G, Cherukuri, Praveen F, Maskeri, Baishali, Young, Alice C, Adeyemo, Adebowale, Rotimi, Charles N

Volltext

UGT1A1 is a major locus influencing bilirubin levels in African Americans von CHEN, Guanjie, RAMOS, Edward, BENTLEY, Amy R, HUICHUN XU, CHARLES, Bashira A, CHRISTMAN, Michael F, ROTIMI, Charles N, ADEYEMO, Adebowale, SHRINER, Daniel, JIE ZHOU, DOUMATEY, Ayo P, HUANG, Hanxia, ERDOS, Michael R, GERRY, Norman P, HERBERT, Alan

Volltext

A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals von Chen, Guanjie, Adeyemo, Adebowale, Zhou, Jie, Doumatey, Ayo P., Bentley, Amy R., Ekoru, Kenneth, Shriner, Daniel, Rotimi, Charles N.

Volltext

The African Genome Variation Project shapes medical genetics in Africa von Gurdasani, Deepti, Carstensen, Tommy, Tekola-Ayele, Fasil, Pagani, Luca, Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Karthikeyan, Savita, Iles, Louise, Pollard, Martin O., Choudhury, Ananyo, Ritchie, Graham R. S., Xue, Yali, Asimit, Jennifer, Nsubuga, Rebecca N., Young, Elizabeth H., Pomilla, Cristina, Kivinen, Katja, Rockett, Kirk, Kamali, Anatoli, Doumatey, Ayo P., Asiki, Gershim, Seeley, Janet, Sisay-Joof, Fatoumatta, Jallow, Muminatou, Tollman, Stephen, Mekonnen, Ephrem, Ekong, Rosemary, Oljira, Tamiru, Bradman, Neil, Bojang, Kalifa, Ramsay, Michele, Adeyemo, Adebowale, Bekele, Endashaw, Motala, Ayesha, Norris, Shane A., Pirie, Fraser, Kaleebu, Pontiano, Kwiatkowski, Dominic, Tyler-Smith, Chris, Rotimi, Charles, Zeggini, Eleftheria, Sandhu, Manjinder S.

Volltext

High sensitivity C-reactive protein (Hs-CRP) remains highly stable in long-term archived human serum von Doumatey, Ayo P., Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles

Volltext

Genome-wide association study of type 2 diabetes in Africa von Chen, Ji, Sun, Meng, Adeyemo, Adebowale, Pirie, Fraser, Carstensen, Tommy, Pomilla, Cristina, Doumatey, Ayo P., Chen, Guanjie, Young, Elizabeth H., Sandhu, Manjinder, Morris, Andrew P., Barroso, Inês, McCarthy, Mark I., Mahajan, Anubha, Wheeler, Eleanor, Rotimi, Charles N., Motala, Ayesha A.

Volltext