Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals von Maeda, Toru, Sakabe, Tomoya, Sunaga, Ataru, Sakai, Keiko, Rivera, Alexander L., Keene, Douglas R., Sasaki, Takako, Stavnezer, Edward, Iannotti, Joseph, Schweitzer, Ronen, Ilic, Dusko, Baskaran, Harihara, Sakai, Takao

Volltext

Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization von Thrivikraman, Greeshma, Athirasala, Avathamsa, Gordon, Ryan, Zhang, Limin, Bergan, Raymond, Keene, Douglas R., Jones, James M., Xie, Hua, Chen, Zhiqiang, Tao, Jinhui, Wingender, Brian, Gower, Laurie, Ferracane, Jack L., Bertassoni, Luiz E.

Volltext

Novel Model of Tendon Regeneration Reveals Distinct Cell Mechanisms Underlying Regenerative and Fibrotic Tendon Healing von Howell, Kristen, Chien, Chun, Bell, Rebecca, Laudier, Damien, Tufa, Sara F., Keene, Douglas R., Andarawis-Puri, Nelly, Huang, Alice H.

Volltext

In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial von Gurevich, Irina, Agarwal, Pooja, Zhang, PeiPei, Dolorito, John A., Oliver, Stacie, Liu, Henry, Reitze, Nicholas, Sarma, Nikhil, Bagci, Isin Sinem, Sridhar, Kunju, Kakarla, Visesha, Yenamandra, Vamsi K., O’Malley, Mark, Prisco, Marco, Tufa, Sara F., Keene, Douglas R., South, Andrew P., Krishnan, Suma M., Marinkovich, M. Peter

Volltext

Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype von Stone, William, Strege, Chloe, Miller, William, Geurts, Aron M, Grzybowski, Michael, Riddle, Megan, Lees, Christopher, Eide, Cindy, Keene, Douglas R, Tufa, Sara F, Seelig, Davis, McGrath, John, Tolar, Jakub

Volltext

QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study von Bornert, Olivier, Hogervorst, Marieke, Nauroy, Pauline, Bischof, Johannes, Swildens, Jim, Athanasiou, Ioannis, Tufa, Sara F., Keene, Douglas R., Kiritsi, Dimitra, Hainzl, Stefan, Murauer, Eva M., Marinkovich, M. Peter, Platenburg, Gerard, Hausser, Ingrid, Wally, Verena, Ritsema, Tita, Koller, Ulrich, Haisma, Elisabeth M., Nyström, Alexander

Volltext

Microenvironmental regulation by fibrillin-1 von Sengle, Gerhard, Tsutsui, Ko, Keene, Douglas R, Tufa, Sara F, Carlson, Eric J, Charbonneau, Noe L, Ono, Robert N, Sasaki, Takako, Wirtz, Mary K, Samples, John R, Fessler, Liselotte I, Fessler, John H, Sekiguchi, Kiyotoshi, Hayflick, Susan J, Sakai, Lynn Y

Volltext

Tgfβ signaling is critical for maintenance of the tendon cell fate von Tan, Guak-Kim, Pryce, Brian A, Stabio, Anna, Brigande, John V, Wang, ChaoJie, Xia, Zheng, Tufa, Sara F, Keene, Douglas R, Schweitzer, Ronen

Volltext

Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons von Murchison, Nicholas D, Price, Brian A, Conner, David A, Keene, Douglas R, Olson, Eric N, Tabin, Clifford J, Schweitzer, Ronen

Volltext

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice von Sengle, Gerhard, Carlberg, Valerie, Tufa, Sara F, Charbonneau, Noe L, Smaldone, Silvia, Carlson, Eric J, Ramirez, Francesco, Keene, Douglas R, Sakai, Lynn Y

Volltext

Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa von Wagner, John E, Ishida-Yamamoto, Akemi, McGrath, John A, Hordinsky, Maria, Keene, Douglas R, Woodley, David T, Chen, Mei, Riddle, Megan J, Osborn, Mark J, Lund, Troy, Dolan, Michelle, Blazar, Bruce R, Tolar, Jakub

Volltext

Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure von Agarwal, Pallavi, Zwolanek, Daniela, Keene, Douglas R., Schulz, Jan-Niklas, Blumbach, Katrin, Heinegård, Dick, Zaucke, Frank, Paulsson, Mats, Krieg, Thomas, Koch, Manuel, Eckes, Beate

Volltext

Sex, pregnancy and aortic disease in Marfan syndrome von Renard, Marjolijn, Muiño-Mosquera, Laura, Manalo, Elise C, Tufa, Sara, Carlson, Eric J, Keene, Douglas R, De Backer, Julie, Sakai, Lynn Y

Volltext

Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis von Iwasaki, Ayumi, Sakai, Keiko, Moriya, Kei, Sasaki, Takako, Keene, Douglas R., Akhtar, Riaz, Miyazono, Takayoshi, Yasumura, Satoshi, Watanabe, Masatoshi, Morishita, Shin, Sakai, Takao

Volltext

Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture von Schlesinger, Saundra Y., Seo, Seongkyung, Pryce, Brian A., Tufa, Sara F., Keene, Douglas R., Huang, Alice H., Schweitzer, Ronen

Volltext

Musculoskeletal integration at the wrist underlies the modular development of limb tendons von Huang, Alice H, Riordan, Timothy J, Pryce, Brian, Weibel, Jennifer L, Watson, Spencer S, Long, Fanxin, Lefebvre, Veronique, Harfe, Brian D, Stadler, H Scott, Akiyama, Haruhiko, Tufa, Sara F, Keene, Douglas R, Schweitzer, Ronen

Volltext

New insights into the structural role of EMILINs within the human skin microenvironment von Schiavinato, Alvise, Marcous, Fady, Zuk, Alexandra V., Keene, Douglas R., Tufa, Sara F., Mosquera, Laura M., Zigrino, Paola, Mauch, Cornelia, Eckes, Beate, Francois, Katrien, De Backer, Julie, Hunzelmann, Nicolas, Moinzadeh, Pia, Krieg, Thomas, Callewaert, Bert, Sengle, Gerhard

Volltext

The Atypical Homeodomain Transcription Factor Mohawk Controls Tendon Morphogenesis von Liu, Wenjin, Watson, Spencer S., Lan, Yu, Keene, Douglas R., Ovitt, Catherine E., Liu, Han, Schweitzer, Ronen, Jiang, Rulang

Volltext

Reticulocalbin 3 is involved in postnatal tendon development by regulating collagen fibrillogenesis and cellular maturation von Park, Na Rae, Shetye, Snehal S., Bogush, Igor, Keene, Douglas R., Tufa, Sara, Hudson, David M., Archer, Marilyn, Qin, Ling, Soslowsky, Louis J., Dyment, Nathaniel A., Joeng, Kyu Sang

Volltext

Characterization of TGFβ1-induced tendon-like structure in the scaffold-free three-dimensional tendon cell culture system von Koo, Bon-hyeock, Lee, Yeon-Ju, Park, Na Rae, Heo, Su Chin, Hudson, David M., Fernandes, Aysel A., Friday, Chet S., Hast, Michael W., Corr, David T., Keene, Douglas R., Tufa, Sara F., Dyment, Nathaniel A., Joeng, Kyu Sang

Volltext