Guidelines for the welfare and use of animals in cancer research von Workman, P, Aboagye, E O, Balkwill, F, Balmain, A, Bruder, G, Chaplin, D J, Double, J A, Everitt, J, Farningham, D A H, Glennie, M J, Kelland, L R, Robinson, V, Stratford, I J, Tozer, G M, Watson, S, Wedge, S R, Eccles, S A

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The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function von Burger, Angelika M, Dai, Fangping, Schultes, Christoph M, Reszka, Anthony P, Moore, Michael J, Double, John A, Neidle, Stephen

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Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo von Leong, C-O, Gaskell, M, Martin, E A, Heydon, R T, Farmer, P B, Bibby, M C, Cooper, P A, Double, J A, Bradshaw, T D, Stevens, M F G

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Quantitative angiogenesis assays in vivo: a review von HASAN, Jurjees, SHNYDER, S. D, BIBBY, M, DOUBLE, J. A, BICKNELL, R, JAYSON, G. C

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Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles von Bradshaw, Tracey D, Bibby, Michael C, Double, John A, Fichtner, Iduna, Cooper, Patricia A, Alley, Michael C, Donohue, Susan, Stinson, Sherman F, Tomaszewjski, Joseph E, Sausville, Edward A, Stevens, Malcolm F G

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Methionine dependence of tumours: A biochemical strategy for optimizing paclitaxel chemosensitivity in vitro von Pavillard, Valerie, Nicolaou, Anna, Double, John A., Phillips, Roger M.

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Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid von Laws, AL, Matthew, AM, Double, JA, Bibby, MC

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Inhibition of telomerase activity by cisplatin in human testicular cancer cells von Burger, A.M., Double, J.A., Newell, D.R.

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Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent von Patterson, L H, McKeown, S R, Ruparelia, K, Double, J A, Bibby, M C, Cole, S, Stratford, I J

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Analysis of cell-cycle kinetics and sulfur amino acid metabolism in methionine-dependent tumor cell lines; the effect of homocysteine supplementation von Pavillard, Valérie, Drbal, Abedalnaser A.A., Swaine, David J., Phillips, Roger M., Double, John A., Nicolaou, Anna

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A novel strategy for NQO1 (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9 von Choudry, G A, Stewart, P A Hamilton, Double, J A, Krul, M R L, Naylor, B, Flannigan, G M, Shah, T K, Brown, J E, Phillips, R M

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A pharmacological approach for the selection of potential anticancer agents von Double, John A

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Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy von Burger, AM, Bibby, MC, Double, JA

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Pharmacokinetics of PK1 and Doxorubicin in Experimental Colon Tumor Models with Differing Responses to PK1 von LOADMAN, P. M, BIBBY, M. C, DOUBLE, J. A, AL-SHAKHAA, W. M, DUNCAN, R

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Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse von UCHEGBU, I. E, DOUBLE, J. A, TURTON, J. A, FLORENCE, A. T

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Cellular uptake, cytotoxicity and DNA-binding studies of the novel imidazoacridinone antineoplastic agent C1311 von Burger, A M, Jenkins, T C, Double, J A, Bibby, M C

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Angiogenesis in the hollow fiber tumor model influences drug delivery to tumor cells : Implications for anticancer drug screening programs von PHILLIPS, R. M, PEARCE, J, LOADMAN, P. M, BIBBY, M. C, COOPER, P. A, SWAINE, D. J, DOUBLE, J. A

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Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mito... von Phillips, Roger M., Burger, Angelika M., Fiebig, Heinz-Herbert, Double, John A.

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Telomeres and Telomerase: Methods and Protocols von Double, John A, Thompson, Michael J

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Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer von Burger, AM, Double, JA, Konopa, J, Bibby, MC

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