Inhaled mRNA therapy for treatment of cystic fibrosis: Interim results of a randomized, double‐blind, placebo‐controlled phase 1/2 clinical study von Rowe, S.M., Zuckerman, J.B., Dorgan, D., Lascano, J., McCoy, K., Jain, M., Schechter, M.S., Lommatzsch, S., Indihar, V., Lechtzin, N., McBennett, K., Callison, C., Brown, C., Liou, T.G., MacDonald, K.D., Nasr, S.Z., Bodie, S., Vaughn, M., Meltzer, E.B., Barbier, A.J.

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185 Use of the hemoglobin A1c test as a screening tool for cystic fibrosis related diabetes von Nicolo, M, Dorgan, D, Ferrin, M, Holsclaw, D, Smith, S, Hadjiliadis, D

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Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis von Chalmers, James D, Haworth, Charles S, Metersky, Mark L, Loebinger, Michael R, Blasi, Francesco, Sibila, Oriol, O’Donnell, Anne E, Sullivan, Eugene J, Mange, Kevin C, Fernandez, Carlos, Zou, Jun, Daley, Charles L

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WS02.3 Randomized, double-blind (DB), placebo-controlled study and open-label (OL) extension of liposomal amikacin for inhalation (LAI) in patients with refractory nontuberculous m... von Olivier, K.N, Eagle, G, McGinnis, J.P, Micioni, L, Daley, C.L, Winthrop, K.L, Ruoss, S, Addrizzo-Harris, D.J, Flume, P, Dorgan, D, Salathe, M, Brown-Elliott, B.A, Wallace, R, Griffith, D.E

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132 Current trends in sputum expectoration and respiratory sampling for research: A single-center experience von Hong, G., O’Dea, A., Borowiec, A., Sheikh, S., Dorgan, D., Hadjiliadis, D.

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WS19.1 Using microsystems methods to improve nutritional outcomes in an adult CF center: a quality improvement (QI) initiative von Ferrin, M, Nicolo, M, Dorgan, D, Hadjiliadis, D, Holsclaw, D, Shechtman, M, Kreider, P, Robinson, C.B

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406: Impact of highly-effective CFTR modulation on the microbial environment in cystic fibrosis von Hong, G., Lipscombe, C., Daniel, S., O’Dea, A., Bittinger, K., Dorgan, D., Hadjiliadis, D.

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Geriatric cystic fibrosis: clinical features of patients over 50 years of age von Hadjiliadis, D, Kaplan, M, Ferrin, M, Imbesi, G, Dorgan, D, Holsclaw, D

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WS05.06 Phase 1/2a randomized, double-blind, placebo-controlled study: safety, Pk, and Efficacy outcome measures of inhaled Gallium Citrate (AR-501) in P Aeruginosa infected Cystic... von Cohen, A., Lechtzin, N., Boas, S., Pena, T., McBennett, K., Gross, J., Dorgan, D., Couch, L., Hoffman, L., Saavedra, M., Hisert, K., Stevens-Brogan, M., Plascencia, C., Deans, L., Kelson, A., Lovalenti, P., Woo, J., Truong, V., Jafri, H.S.

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Evans−Tishchenko Coupling of Heteroaryl Aldehydes von Dorgan, Philip D, Durrani, Jamie, Cases-Thomas, Manuel J, Hulme, Alison N

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544: Safety and tolerability of single and repeat doses of MRT5005, an inhaled CFTR mRNA replacement therapy, in adult CF patients von Rowe, S., Dorgan, D., Lascano, J., Zuckerman, J., McCoy, K., Jain, M., Schechter, M., Lommatzsch, S., Indihar, V., Lechtzin, N., McBennett, K., Callison, J., Brown, C., Liou, T., MacDonald, K., Nasr, S., Bodie, S., Meltzer, E., Barbier, A.

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B103 FIXING A HOLE: ADVANCES IN DIAGNOSTIC AND THERAPEUTIC BRONCHOSCOPY: Management Of Airway Complications Following Lung Transplantation von Frye, L K, Pena, T, Ahya, V N, Lee, J, Shah, R J, Dorgan, D, Christie, J D, Hadjiliadis, D, Haas, A, Sterman, D H, Moon, E K, Bessich, J L, Cantu, E, Diamond, J, Lanfranco, A

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Subgroup Analyses Of Baseline Demographics And Efficacy In Patients With Refractory Nontuberculous Mycobact... von Winthrop, K L, Eagle, G, McGinnis, J P, Micioni, L, Daley, C L, Ruoss, S J, Addrizzo-Harris, D J, Flume, P A, Dorgan, D J, Salathe, M, Brown-Elliott, B A, Wallace, R J, Griffith, D E, Olivier, K N

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Analysis Of Functional Exercise Capacity (via The Six-Minute Walk Test [6mwt]) And Culture Negativity In Pa... von Ruoss, S J, Eagle, G, McGinnis, J P, Micioni, L, Daley, C L, Winthrop, K L, Addrizzo-Harris, D J, Flume, P A, Dorgan, D J, Salathe, M, Griffith, D E, Olivier, K N

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C27 DIAGNOSIS AND TREATMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: A Randomized, Double-Blind, Placebo-Controlled Study Of Liposomal Amikacin For Inhalation (arikace®) In Patie... von Olivier, K N, Gupta, R, Daley, C L, Winthrop, K L, Ruoss, S, Addrizzo-Harris, D J, Flume, P, Dorgan, D, Salathe, M A, Brown-Elliott, B A, Wallace, R J, Griffith, D E

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D108 DIAGNOSIS AND MANAGEMENT OF NONTUBERCULOUS MYCOBACTERIA INFECTIONS: Efficacy Of Liposomal Amikacin For Inhalation (lai) In Achieving Nontuberculous Mycobacteria (ntm) Culture... von Biller, J A, Eagle, G, McGinnis, J P, Micioni, L, Daley, C L, Winthrop, K L, Ruoss, S J, Addrizzo-Harris, D J, Flume, P A, Dorgan, D J, Salathe, M, Brown-Elliott, B A, Wallace, R J, Griffith, D E, Olivier, K N

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Evaas-Tishchenko Coupling of Heteroaryl Aldehydes von DORGAN, Philip D, DURRANI, Jamie, CASES-THOMAS, Manuel J, HULME, Alison N

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l-Carnitine: therapeutic strategy for metabolic encephalopathy von Kim, C.S., Dorgan, D.R., Roe, C.R.

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Evans-Tishchenko/ring-closing alkyne metathesis approach toward the synesis of Disorzole C1 von Dorgan, Philip D

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Phenytoin (dilantin)‐induced cleft lip and palate in a/j mice: A scanning and transmission electron microscopic study von Sulik, K. K., Johnston, M. C., Ambrose, L. J. H., Dorgan, D.

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