Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma von Bixel, Kristin, Saini, Uksha, Kumar Bid, Hemant, Fowler, John, Riley, Maria, Wanner, Ross, Deepa Priya Dorayappan, Kalpana, Rajendran, Sneha, Konishi, Ikuo, Matsumura, Noriomi, Cohn, David E., Selvendiran, Karuppaiyah

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Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomes von Hisey, Colin L, Dorayappan, Kalpana Deepa Priya, Cohn, David E, Selvendiran, Karuppaiyah, Hansford, Derek J

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Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins von Dorayappan, Kalpana Deepa Priya, Wanner, Ross, Wallbillich, John J., Saini, Uksha, Zingarelli, Roman, Suarez, Adrian A., Cohn, David E., Selvendiran, Karuppaiyah

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The biological significance and clinical applications of exosomes in ovarian cancer von Dorayappan, Kalpana Deepa Priya, Wallbillich, John J, Cohn, David E, Selvendiran, Karuppaiyah

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High Glucose-Mediated STAT3 Activation in Endometrial Cancer Is Inhibited by Metformin: Therapeutic Implications for Endometrial Cancer von Wallbillich, John J, Josyula, Srirama, Saini, Uksha, Zingarelli, Roman A, Dorayappan, Kalpana Deepa Priya, Riley, Maria K, Wanner, Ross A, Cohn, David E, Selvendiran, Karuppaiyah

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Correction: Targeting TMEM205 mediated drug resistance in ovarian clear cell carcinoma using oncolytic virus von Saini, Uksha, Smith, Brentley Q, Dorayappan, Kalpana Deepa Priya, Yoo, Ji Young, Maxwell, G Larry, Kaur, Balveen, Konishi, Ikuo, O'Malley, David, Cohn, David E, Selvendiran, Karuppaiyah

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Targeting TMEM205 mediated drug resistance in ovarian clear cell carcinoma using oncolytic virus von Saini, Uksha, Smith, Brentley Q, Dorayappan, Kalpana Deepa Priya, Yoo, Ji Young, Maxwell, G Larry, Kaur, Balveen, Konishi, Ikuo, O'Malley, David, Cohn, David E, Selvendiran, Karuppaiyah

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ISG15 mediates the function of extracellular vesicles in promoting ovarian cancer progression and metastasis von Dorayappan, Kalpana Deepa Priya, Wagner, Vincent, Park, Dongju, Newcomer, Meghan M., Lightfoot, Michelle D. S., Kalaiyarasan, Deepika, Sakaue, Takahiko, Khadraoui, Wafa, Yu, Lianbo, Wang, Qi‐En, Maxwell, G. Larry, O'Malley, David, Pollock, Raphael E., Cohn, David E., Selvendiran, Karuppaiyah

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Circulating exosomal TMEM205 protein expression for early prediction of platinum-resistance in high grade serous ovarian cancer (255) von Wagner, Vincent, Dorayappan, Kalpana Deepa Priya, Cosgrove, Casey, Cohn, David, Karuppaiyah, Selvendiran

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A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer von Dorayappan, Kalpana Deepa Priya, Gardner, Miranda L, Hisey, Colin L, Zingarelli, Roman A, Smith, Brentley Q, Lightfoot, Michelle D S, Gogna, Rajan, Flannery, Meghan M, Hays, John, Hansford, Derek J, Freitas, Michael A, Yu, Lianbo, Cohn, David E, Selvendiran, Karuppaiyah

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Obesity-induced extracellular vesicles proteins drive the endometrial cancer pathogenesis: therapeutic potential of HO-3867 and Metformin von Sakaue, Takahiko, Dorayappan, Kalpana Deepa Priya, Zingarelli, Roman, Khadraoui, Wafa, Anbalagan, Muralidharan, Wallbillich, John, Bognar, Balazs, Wanner, Ross, Cosgrove, Casey, Suarez, Adrian, Koga, Hironori, Maxwell, G. Larry, O’Malley, David M., Cohn, David E., Selvendiran, Karuppaiyah

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Identifying the role of transmembrane protein TMEM205 in promoting platinum resistance in ovarian cancer through exosomal efflux of platinum agents von Calo, Corinne, Dorayappan, Kalpana Deepa Priya, Wagner, Vincent, Werner, Marissa, Wang, Qi-En, Backes, Floor, Maxwell, G. Larry, Cohn, David, Karuppaiyah, Selvendiran

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Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomesElectronic supplementary information (ESI) available: 4 figures and 2 v... von Hisey, Colin L, Dorayappan, Kalpana Deepa Priya, Cohn, David E, Selvendiran, Karuppaiyah, Hansford, Derek J

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Development of a Targeted Ultrasound Microbubble for Early Detection of Ovarian Cancer von Flannery, Meghan M., Dorayappan, Kalpana Deepa Priya, Calo, Corinne A., Kalmar, Eileen L., Tweedle, Michael F., Suarez, Adrian A., Cohn, David E., Karuppaiyah, Selvendiran

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Tissue factor as a novel diagnostic target for early detection of ovarian cancer using ultrasound microbubbles von Newcomer, Meghan M., Dorayappan, Kalpana Deepa Priya, Wagner, Vincent, Suarez, Adrian A., Calo, Corinne A., Kalmar, Eileen L., Maxwell, G. Larry, O’Malley, David, Cohn, David E., Tweedle, Michael F., Selvendiran, Karuppaiyah

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Aberrant expression of TMEM205 signaling promotes platinum resistance in ovarian cancer: An implication for the antitumor potential of DAP compound von Calo, Corinne A., Smith, Brentley Q., Dorayappan, Kalpana Deepa Priya, Saini, Uksha, Lightfoot, Michelle, Wagner, Vincent, Kalaiyarasan, Deepika, Cosgrove, Casey, Wang, Qi-En, Maxwell, G. Larry, Kálai, Tamás, Kuppusamy, Periannan, Cohn, David E., Selvendiran, Karuppaiyah

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Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells von Madan, Esha, Palma, António M, Vudatha, Vignesh, Kumar, Amit, Bhoopathi, Praveen, Wilhelm, Jochen, Bernas, Tytus, Martin, Patrick C, Bilolikar, Gaurav, Gogna, Aenya, Peixoto, Maria Leonor, Dreier, Isabelle, Araujo, Thais Fenz, Garre, Elena, Gustafsson, Anna, Dorayappan, Kalpana Deepa Priya, Mamidi, Narsimha, Sun, Zhaoyu, Yekelchyk, Michail, Accardi, Davide, Olsen, Amalie Lykke, Lin, Lin, Titelman, Asaf Ashkenazy, Bianchi, Michael, Jessmon, Phil, Farid, Elnaz Abbasi, Pradhan, Anjan K, Neufeld, Lena, Yeini, Eilam, Maji, Santanu, Pelham, Christopher J, Kim, Hyobin, Oh, Daniel, Rolfsnes, Hans Olav, Marques, Rita C, Lu, Amy, Nagane, Masaki, Chaudhary, Sahil, Gupta, Kartik, Gogna, Keshav C, Bigio, Ana, Bhoopathi, Karthikeya, Mannangatti, Padmanabhan, Achary, K Gopinath, Akhtar, Javed, Belião, Sara, Das, Swadesh, Correia, Isabel, da Silva, Cláudia L, Fialho, Arsénio M, Poellmann, Michael J, Javius-Jones, Kaila, Hawkridge, Adam M, Pal, Sanya, Shree, Kumari S, Rakha, Emad A, Khurana, Sambhav, Xiao, Gaoping, Zhang, Dongyu, Rijal, Arjun, Lyons, Charles, Grossman, Steven R, Turner, David P, Pillappa, Raghavendra, Prakash, Karanvir, Gupta, Gaurav, Robinson, Gary L W G, Koblinski, Jennifer, Wang, Hongjun, Singh, Gita, Singh, Sujay, Rayamajhi, Sagar, Bacolod, Manny D, Richards, Hope, Sayeed, Sadia, Klein, Katherine P, Chelmow, David, Satchi-Fainaro, Ronit, Selvendiran, Karuppaiyah, Connolly, Denise, Thorsen, Frits Alan, Bjerkvig, Rolf, Nephew, Kenneth P, Idowu, Michael O, Kühnel, Mark P, Moskaluk, Christopher, Hong, Seungpyo, Redmond, William L, Landberg, Göran, Lopez-Beltran, Antonio, Poklepovic, Andrew S, Sanyal, Arun, Fisher, Paul B, Church, George M, Menon, Usha, Drapkin, Ronny, Godwin, Andrew K, Luo, Yonglun, Ackermann, Maximilian, Tzankov, Alexandar

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Abstract 5798: Exosomal oncogenic proteins promote tumor progression, metastasis and chemoresistance in ovarian cancer von Dorayappan, Kalpana Deepa Priya, Wanner, Ross A., Zingarelli, Roman A., Saini, Uksha, Karuppaiyah, Selvendiran, Cohn, David E.

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Abstract 5888: Tmem 205-mediated cisplatin resistance in ovarian clear cell carcinoma (OCCC) is overcome by herpes simplex virus (oHSV)/cisplatin combination therapy von Saini, Uksha, Riley, Maria, Dorayappan, Kalpana Deepa, Bolyard, Chelsea, Kaur, Balveen, Zingarelli, Roman, Konishi, Ikuo, Kuppusamy, Periannan, Maxwell, George Larry, Cohn, David E., Selvendiran, Karuppaiyah

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Abstract LB156: Identified the ISG15 mediated extracellular vesicles drives ovarian cancer progression and metastasis: extracellular vesicular ISG15 is a potential biomarker and th... von Dorayappan, Kalpana Deepa Priya, Wagner, Vincent, Park, Dongju, Newcomer, Meghan M., Lightfoot, Michelle DS, Kalaiyarasan, Deepika, Sakaue, Takahiko, Khadraoui, Wafa, Cosgrove, Casey, Maxwell, Larry J., Wang, Qi-En Wang, O’Malley, David, Pollock, Raphael E., Cohn, David E., Karuppaiyah, Selvendiran

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