A high‐throughput shotgun mutagenesis approach to mapping B‐cell antibody epitopes von Davidson, Edgar, Doranz, Benjamin J.

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Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein von Suryadevara, Naveenchandra, Shrihari, Swathi, Gilchuk, Pavlo, VanBlargan, Laura A., Binshtein, Elad, Zost, Seth J., Nargi, Rachel S., Sutton, Rachel E., Winkler, Emma S., Chen, Elaine C., Fouch, Mallorie E., Davidson, Edgar, Doranz, Benjamin J., Chen, Rita E., Shi, Pei-Yong, Carnahan, Robert H., Thackray, Larissa B., Diamond, Michael S., Crowe, James E.

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Mxra8 is a receptor for multiple arthritogenic alphaviruses von Zhang, Rong, Kim, Arthur S., Fox, Julie M., Nair, Sharmila, Basore, Katherine, Klimstra, William B., Rimkunas, Rebecca, Fong, Rachel H., Lin, Hueylie, Poddar, Subhajit, Crowe, James E., Doranz, Benjamin J., Fremont, Daved H., Diamond, Michael S.

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Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection von Flyak, Andrew I., Shen, Xiaoli, Murin, Charles D., Turner, Hannah L., David, Joshua A., Fusco, Marnie L., Lampley, Rebecca, Kose, Nurgun, Ilinykh, Philipp A., Kuzmina, Natalia, Branchizio, Andre, King, Hannah, Brown, Leland, Bryan, Christopher, Davidson, Edgar, Doranz, Benjamin J., Slaughter, James C., Sapparapu, Gopal, Klages, Curtis, Ksiazek, Thomas G., Saphire, Erica Ollmann, Ward, Andrew B., Bukreyev, Alexander, Crowe, James E.

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Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape von Ku, Zhiqiang, Xie, Xuping, Davidson, Edgar, Ye, Xiaohua, Su, Hang, Menachery, Vineet D., Li, Yize, Yuan, Zihao, Zhang, Xianwen, Muruato, Antonio E., i Escuer, Ariadna Grinyo, Tyrell, Breanna, Doolan, Kyle, Doranz, Benjamin J., Wrapp, Daniel, Bates, Paul F., McLellan, Jason S., Weiss, Susan R., Zhang, Ningyan, Shi, Pei-Yong, An, Zhiqiang

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Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8⁺ T cells von Weiskopf, Daniela, Angelo, Michael A, de Azeredo, Elzinandes L, Sidney, John, Greenbaum, Jason A, Fernando, Anira N, Broadwater, Anne, Kolla, Ravi V, De Silva, Aruna D, de Silva, Aravinda M, Mattia, Kimberly A, Doranz, Benjamin J, Grey, Howard M, Shresta, Sujan, Peters, Bjoern, Sette, Alessandro

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Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies von Davidson, Edgar, Bryan, Christopher, Fong, Rachel H, Barnes, Trevor, Pfaff, Jennifer M, Mabila, Manu, Rucker, Joseph B, Doranz, Benjamin J

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Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices von Wescott, Melanie P., Kufareva, Irina, Paes, Cheryl, Goodman, Jason R., Thaker, Yana, Puffer, Bridget A., Berdougo, Eli, Rucker, Joseph B., Handel, Tracy M., Doranz, Benjamin J.

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Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress von Fox, Julie M., Long, Feng, Edeling, Melissa A., Lin, Hueylie, van Duijl-Richter, Mareike K.S., Fong, Rachel H., Kahle, Kristen M., Smit, Jolanda M., Jin, Jing, Simmons, Graham, Doranz, Benjamin J., Crowe, James E., Fremont, Daved H., Rossmann, Michael G., Diamond, Michael S.

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Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis von Gopal, Radhika, Jackson, Kelli, Tzarum, Netanel, Kong, Leopold, Ettenger, Andrew, Guest, Johnathan, Pfaff, Jennifer M, Barnes, Trevor, Honda, Andrew, Giang, Erick, Davidson, Edgar, Wilson, Ian A, Doranz, Benjamin J, Law, Mansun

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Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals von Chen, Elaine C., Gilchuk, Pavlo, Zost, Seth J., Suryadevara, Naveenchandra, Winkler, Emma S., Cabel, Carly R., Binshtein, Elad, Chen, Rita E., Sutton, Rachel E., Rodriguez, Jessica, Day, Samuel, Myers, Luke, Trivette, Andrew, Williams, Jazmean K., Davidson, Edgar, Li, Shuaizhi, Doranz, Benjamin J., Campos, Samuel K., Carnahan, Robert H., Thorne, Curtis A., Diamond, Michael S., Crowe, James E.

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Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin von Greene, Tiffani A, Alarcon, Suzanne, Thomas, Anu, Berdougo, Eli, Doranz, Benjamin J, Breslin, Paul A S, Rucker, Joseph B

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Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection von Kinchen, Valerie J., Zahid, Muhammad N., Flyak, Andrew I., Soliman, Mary G., Learn, Gerald H., Wang, Shuyi, Davidson, Edgar, Doranz, Benjamin J., Ray, Stuart C., Cox, Andrea L., Crowe, James E., Bjorkman, Pamela J., Shaw, George M., Bailey, Justin R.

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Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability von Zhao, Xuelian, Howell, Katie A., He, Shihua, Brannan, Jennifer M., Wec, Anna Z., Davidson, Edgar, Turner, Hannah L., Chiang, Chi-I., Lei, Lin, Fels, J. Maximilian, Vu, Hong, Shulenin, Sergey, Turonis, Ashley N., Kuehne, Ana I., Liu, Guodong, Ta, Mi, Wang, Yimeng, Sundling, Christopher, Xiao, Yongli, Spence, Jennifer S., Doranz, Benjamin J., Holtsberg, Frederick W., Ward, Andrew B., Chandran, Kartik, Dye, John M., Qiu, Xiangguo, Li, Yuxing, Aman, M. Javad

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The emergence of cell-based protein arrays to test for polyspecific off-target binding of antibody therapeutics von Norden, Diana M, Navia, Carmen T, Sullivan, Jonathan T, Doranz, Benjamin J

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Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis von Jin, Jing, Liss, Nathan M., Chen, Dong-Hua, Liao, Maofu, Fox, Julie M., Shimak, Raeann M., Fong, Rachel H., Chafets, Daniel, Bakkour, Sonia, Keating, Sheila, Fomin, Marina E., Muench, Marcus O., Sherman, Michael B., Doranz, Benjamin J., Diamond, Michael S., Simmons, Graham

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Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus von Smith, Scott A., Silva, Laurie A., Fox, Julie M., Flyak, Andrew I., Kose, Nurgun, Sapparapu, Gopal, Khomandiak, Solomiia, Ashbrook, Alison W., Kahle, Kristen M., Fong, Rachel H., Swayne, Sherri, Doranz, Benjamin J., McGee, Charles E., Heise, Mark T., Pal, Pankaj, Brien, James D., Austin, S. Kyle, Diamond, Michael S., Dermody, Terence S., Crowe, James E.

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Breaking barriers in antibody discovery: harnessing divergent species for accessing difficult and conserved drug targets von Banik, Soma S.R., Kushnir, Natasha, Doranz, Benjamin J., Chambers, Ross

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Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes von Li, Leike, Meng, Weixu, Horton, Melanie, DiStefano, Daniel R, Thoryk, Elizabeth A, Pfaff, Jennifer M, Wang, Qihui, Salazar, Georgina T, Barnes, Trevor, Doranz, Benjamin J, Bett, Andrew J, Casimiro, Danilo R, Vora, Kalpit A, An, Zhiqiang, Zhang, Ningyan

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Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein von Gilchuk, Pavlo, Kuzmina, Natalia, Ilinykh, Philipp A., Huang, Kai, Gunn, Bronwyn M., Bryan, Aubrey, Davidson, Edgar, Doranz, Benjamin J., Turner, Hannah L., Fusco, Marnie L., Bramble, Matthew S., Hoff, Nicole A., Binshtein, Elad, Kose, Nurgun, Flyak, Andrew I., Flinko, Robin, Orlandi, Chiara, Carnahan, Robert, Parrish, Erica H., Sevy, Alexander M., Bombardi, Robin G., Singh, Prashant K., Mukadi, Patrick, Muyembe-Tamfum, Jean Jacques, Ohi, Melanie D., Saphire, Erica Ollmann, Lewis, George K., Alter, Galit, Ward, Andrew B., Rimoin, Anne W., Bukreyev, Alexander, Crowe, James E.

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