Tuning the Functionality by Splicing: Factor H and Its Alternative Splice Variant FHL-1 Share a Gene but Not All Functions von Mannes, Marco, Dopler, Arthur, Huber-Lang, Markus, Schmidt, Christoph Q

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Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels von Golomingi, Murielle, Kohler, Jessie, Lamers, Christina, Pouw, Richard B, Ricklin, Daniel, Dobó, József, Gál, Péter, Pál, Gábor, Kiss, Bence, Dopler, Arthur, Schmidt, Christoph Q, Hardy, Elaissa Trybus, Lam, Wilbur, Schroeder, Verena

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Factor H Autoantibodies and Complement-Mediated Diseases von Zhang, Yuzhou, Ghiringhelli Borsa, Nicolo, Shao, Dingwu, Dopler, Arthur, Jones, Michael B, Meyer, Nicole C, Pitcher, Gabriella R, Taylor, Amanda O, Nester, Carla M, Schmidt, Christoph Q, Smith, Richard J H

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Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces von Dopler, Arthur, Stibitzky, Selina, Hevey, Rachel, Mannes, Marco, Guariento, Mara, Höchsmann, Britta, Schrezenmeier, Hubert, Ricklin, Daniel, Schmidt, Christoph Q

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Different Levels of Incomplete Terminal Pathway Inhibition by Eculizumab and the Clinical Response of PNH Patients von Harder, Markus J, Höchsmann, Britta, Dopler, Arthur, Anliker, Markus, Weinstock, Christof, Skerra, Arne, Simmet, Thomas, Schrezenmeier, Hubert, Schmidt, Christoph Q

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117 Complement receptor 1 long homologous repeats (A, B, and C) as a novel tool to study immune-adherence functionality of human erythrocytes von Ghaboosh, Hiba, Dopler, Arthur, Schmidt, Christoph

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212 Determinants resulting in high residual C5 activity in presence of Eculizumab or Coversin von Sichau, Jannik, Berther, Monika, Dopler, Arthur, Schmidt, Christoph Q.

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186 Assessment of immunogenicity in mice and cross-species activity of an engineered complement regulator von Dopler, Arthur, Kistermann, Sophia, Huber-Lang, Markus, Schmidt, Christoph Q.

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Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity von Mannes, Marco, Dopler, Arthur, Zolk, Oliver, Lang, Sophia J., Halbgebauer, Rebecca, Höchsmann, Britta, Skerra, Arne, Braun, Christian K., Huber-Lang, Markus, Schrezenmeier, Hubert, Schmidt, Christoph Q.

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207 Crystal structure of the Factor H domains 8-14 in complex with the Factor H-recruiting peptide 5C6 validates the unprecedented domain arrangement in the central segment of Fact... von Schmidt, Christoph, Bechtler, Clément, Sichau, Jannik, Umnyakova, Ekaterina, Felsch, Jannes, Dopler, Arthur, Ricklin, Daniel, Niessing, Dirk, Monecke, Thomas

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Self versus Nonself Discrimination by the Soluble Complement Regulators Factor H and FHL-1 von Dopler, Arthur, Guntau, Leonie, Harder, Markus J, Palmer, Annette, Höchsmann, Britta, Schrezenmeier, Hubert, Simmet, Thomas, Huber-Lang, Markus, Schmidt, Christoph Q

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Triple-fusion protein (TriFu): A potent, targeted, enzyme-like inhibitor of all three complement activation pathways von Sonnentag, Sophia J., Dopler, Arthur, Kleiner, Katharina, Garg, Brijesh K., Mannes, Marco, Späth, Nadja, Akilah, Amira, Höchsmann, Britta, Schrezenmeier, Hubert, Anliker, Markus, Boyanapalli, Ruby, Huber-Lang, Markus, Schmidt, Christoph Q.

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95 Complement-associated prothrombotic state is caused by MAC-induced lysis of cells von Mannes, Marco, Pechtl, Veronika, Hafner, Susanne, Dopler, Arthur, Eriksson, Oskar, Manivel, Vivek A., Wohlgemuth, Lisa, Messerer, David A.C., Schrezenmeier, Hubert, Ekdahl, Kristina N., Nilsson, Bo, Jacobsen, Eva-Maria, Hoenig, Manfred, Huber-Lang, Markus, Schmidt, Christoph Q., Braun, Christian

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Antibodies and complement are key drivers of thrombosis von Stark, Konstantin, Kilani, Badr, Stockhausen, Sven, Busse, Johanna, Schubert, Irene, Tran, Thuy-Duong, Gaertner, Florian, Leunig, Alexander, Pekayvaz, Kami, Nicolai, Leo, Fumagalli, Valeria, Stermann, Julia, Stephan, Felix, David, Christian, Müller, Martin B., Heyman, Birgitta, Lux, Anja, da Palma Guerreiro, Alexandra, Frenzel, Lukas P., Schmidt, Christoph Q., Dopler, Arthur, Moser, Markus, Chandraratne, Sue, von Brühl, Marie-Luise, Lorenz, Michael, Korff, Thomas, Rudelius, Martina, Popp, Oliver, Kirchner, Marieluise, Mertins, Philipp, Nimmerjahn, Falk, Iannacone, Matteo, Sperandio, Markus, Engelmann, Bernd, Verschoor, Admar, Massberg, Steffen

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Upregulation of Checkpoint Ligand Programmed Death-Ligand 1 in Patients with Paroxysmal Nocturnal Hemoglobinuria Explained by Proximal Complement Activation von Anliker, Markus, Drees, Daniela, Loacker, Lorin, Hafner, Susanne, Griesmacher, Andrea, Hoermann, Gregor, Fux, Vilmos, Schennach, Harald, Hörtnagl, Paul, Dopler, Arthur, Schmidt, Stefan, Bellmann-Weiler, Rosa, Weiss, Günter, Marx-Hofmann, Astrid, Körper, Sixten, Höchsmann, Britta, Schrezenmeier, Hubert, Schmidt, Christoph Q

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A particular role for the factor H splice variant FHL-1 in regulating the alternative pathway von Dopler, Arthur, Guntau, Leonie, Harder, Markus, Palmer, Annette, Simmet, Thomas, Huber-Lang, Markus, Schmidt, Christoph

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Response to Comment on "Self versus Nonself Discrimination by the Soluble Complement Regulators Factor H and FHL-1" von Dopler, Arthur, Guntau, Leonie, Harder, Markus J, Palmer, Annette, Höchsmann, Britta, Schrezenmeier, Hubert, Simmet, Thomas, Huber-Lang, Markus, Schmidt, Christoph Q

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Complement and platelets: prothrombotic cell activation requires membrane attack complex–induced release of danger signals von Mannes, Marco, Pechtl, Veronika, Hafner, Susanne, Dopler, Arthur, Eriksson, Oskar, Manivel, Vivek Anand, Wohlgemuth, Lisa, Messerer, David Alexander Christian, Schrezenmeier, Hubert, Ekdahl, Kristina N., Nilsson, Bo, Jacobsen, Eva-Maria, Hoenig, Manfred, Huber-Lang, Markus, Braun, Christian K., Schmidt, Christoph Q.

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Complement and platelets : prothrombotic cell activation requires membrane attack complex-induced release of danger signals von Mannes, Marco, Pechtl, Veronika, Hafner, Susanne, Dopler, Arthur, Eriksson, Oskar, Manivel, Vivek Anand, Wohlgemuth, Lisa, Messerer, David Alexander Christian, Schrezenmeier, Hubert, Nilsson Ekdahl, Kristina, Nilsson, Bo, Jacobsen, Eva -Maria, Hoenig, Manfred, Huber-Lang, Markus, Braun, Christian K, Schmidt, Christoph Q

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Antibodies and complement are key drivers of thrombosis von Stark, Konstantin, Kilani, Badr, Stockhausen, Sven, Busse, Johanna, Schubert, Irene, Tran, Thuy-Duong, Gaertner, Florian, Leunig, Alexander, Pekayvaz, Kami, Nicolai, Leo, Fumagalli, Valeria, Stermann, Julia, Stephan, Felix, David, Christian, Müller, Martin B, Heyman, Birgitta, Lux, Anja, da Palma Guerreiro, Alexandra, Frenzel, Lukas P, Schmidt, Christoph Q, Dopler, Arthur, Moser, Markus, Chandraratne, Sue, von Brühl, Marie-Luise, Lorenz, Michael, Korff, Thomas, Rudelius, Martina, Popp, Oliver, Kirchner, Marieluise, Mertins, Philipp, Nimmerjahn, Falk, Iannacone, Matteo, Sperandio, Markus, Engelmann, Bernd, Verschoor, Admar, Massberg, Steffen

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