Microscale purification in support of high-throughput medicinal chemistry von Barhate, Chandan L, Donnell, Andrew F, Davies, Merrill, Li, Ling, Zhang, Yong, Yang, Fukang, Black, Regina, Zipp, Greg, Zhang, Yingru, Cavallaro, Cullen L, Priestley, E. Scott, Weller, Harold N

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Total Synthesis of (+)-Apiosporamide: Assignment of Relative and Absolute Configuration von Williams, David R., Kammler, David C., Donnell, Andrew F., Goundry, William R. F.

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Ni/Photoredox-Catalyzed C(sp2)–C(sp3) Cross-Coupling of Alkyl Pinacolboronates and (Hetero)Aryl Bromides von Cauley, Anthony N., Ramirez, Antonio, Barhate, Chandan L., Donnell, Andrew F., Khandelwal, Purnima, Sezen-Edmonds, Melda, Sherwood, Trevor C., Sloane, Jack L., Cavallaro, Cullen L., Simmons, Eric M.

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Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor von Zhang, Yong, Parrish, Karen E, Tortolani, David R, Poss, Michael A, Huang, Audris, Wan, Honghe, Purandare, Ashok V, Donnell, Andrew F, Kempson, James, Hou, Xiaoping, Pawluczyk, Joseph, Yip, Shiuhang, Luk, Emily, Raghavan, Nimmi, Swanson, Jesse, Smalley, James, Murtaza, Anwar, Yang, Zheng, Augustine-Rauch, Karen, Lombardo, Louis J, Borzilleri, Robert

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Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology von He, Liqi, Zhang, Meng Yao, Cox, Matthew, Zhang, Qian, Donnell, Andrew F., Zhang, Yong, Tarby, Christine, Gill, Patrice, Subbaiah, Murugaiah A. M., Ramar, Thangeswaran, Reddy, Maheswara, Puttapaka, Vijaya, Li, Yi-Xin, Sivaprakasam, Prasanna, Critton, David, Mulligan, Dawn, Xie, Chunshan, Ramakrishnan, Radha, Nagar, Jignesh, Dudhgaonkar, Shailesh, Murtaza, Anwar, Oderinde, Martins S., Schieven, Gary L., Mathur, Arvind, Gavai, Ashvinikumar V., Vite, Gregory, Gangwar, Sanjeev, Poudel, Yam B.

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Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology von Poudel, Yam B., He, Liqi, Cox, Matthew, Zhang, Qian, Johnson, Walter L., Cong, Qiang, Cheng, Heng, Chowdari, Naidu S., Tarby, Christine, Donnell, Andrew F., Broekema, Matthais, O’Malley, Daniel P., Zhang, Yong, A. M. Subbaiah, Murugaiah, Kumar, Boda Vijay, Subramani, Lakshumanan, Wang, Bei, Li, Yi-Xin, Sivaprakasam, Prasanna, Critton, David, Mulligan, Dawn, Sandhu, Bhupindar, Xie, Chunshan, Ramakrishnan, Radha, Nagar, Jignesh, Dudhgaonkar, Shailesh, Oderinde, Martins S., Murtaza, Anwar, Schieven, Gary L., Mathur, Arvind, Gavai, Ashvinikumar V., Vite, Gregory, Gangwar, Sanjeev

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Discovery of 4‑Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents von Zhang, Yong, Zhao, Yufen, Tebben, Andrew J, Sheriff, Steven, Ruzanov, Max, Fereshteh, Mark P, Fan, Yi, Lippy, Jonathan, Swanson, Jesse, Ho, Ching-Ping, Wautlet, Barri S, Rose, Anne, Parrish, Karen, Yang, Zheng, Donnell, Andrew F, Zhang, Liping, Fink, Brian E, Vite, Gregory D, Augustine-Rauch, Karen, Fargnoli, Joseph, Borzilleri, Robert M

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Macrocyclic pyrrolobenzodiazepine dimers as antibody-drug conjugate payloads von Donnell, Andrew F., Zhang, Yong, Stang, Erik M., Wei, Donna D., Tebben, Andrew J., Perez, Heidi L., Schroeder, Gretchen M., Pan, Chin, Rao, Chetana, Borzilleri, Robert M., Vite, Gregory D., Gangwar, Sanjeev

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Studies of Azetidin-2-one as a Reactive Enolate Synthon of β‑Alanine for Condensations with Aldehydes and Ketones von Williams, David R, Donnell, Andrew F, Kammler, David C, Ward, Sarah A, Taylor, Levin

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Benzazepinones and Benzoxazepinones as Antagonists of Inhibitor of Apoptosis Proteins (IAPs) Selective for the Second Baculovirus IAP Repeat (BIR2) Domain von Donnell, Andrew F, Michoud, Christophe, Rupert, Kenneth C, Han, Xiaochun, Aguilar, Douglas, Frank, Karl B, Fretland, Adrian J, Gao, Lin, Goggin, Barry, Hogg, J. Heather, Hong, Kyoungja, Janson, Cheryl A, Kester, Robert F, Kong, Norman, Le, Kang, Li, Shirley, Liang, Weiling, Lombardo, Louis J, Lou, Yan, Lukacs, Christine M, Mischke, Steven, Moliterni, John A, Polonskaia, Ann, Schutt, Andrew D, Solis, Dave S, Specian, Anthony, Taylor, Robert T, Weisel, Martin, Remiszewski, Stacy W

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Optimization of Benzodiazepinones as Selective Inhibitors of the X‑Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain von Kester, Robert F, Donnell, Andrew F, Lou, Yan, Remiszewski, Stacy W, Lombardo, Louis J, Chen, Shaoqing, Le, Nam T, Lo, Jennifer, Moliterni, John A, Han, Xiaochun, Hogg, J. Heather, Liang, Weiling, Michoud, Christophe, Rupert, Kenneth C, Mischke, Steven, Le, Kang, Weisel, Martin, Janson, Cheryl A, Lukacs, Christine M, Fretland, Adrian J, Hong, Kyoungja, Polonskaia, Ann, Gao, Lin, Li, Shirley, Solis, Dave S, Aguilar, Doug, Tardell, Christine, Dvorozniak, Mark, Tannu, Shahid, Lee, Edmund C, Schutt, Andy D, Goggin, Barry

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Identification of pyridazino[4,5- b]indolizines as selective PDE4B inhibitors von Donnell, Andrew F., Dollings, Paul J., Butera, John A., Dietrich, Arlene J., Lipinski, Kerri K., Ghavami, Afshin, Hirst, Warren D.

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Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents von Zhang, Yong, Zhao, Yufen, Tebben, Andrew J., Sheriff, Steven, Ruzanov, Max, Fereshteh, Mark P., Fan, Yi, Lippy, Jonathan, Swanson, Jesse, Ho, Ching-Ping, Wautlet, Barri S., Rose, Anne, Parrish, Karen, Yang, Zheng, Donnell, Andrew F., Zhang, Liping, Fink, Brian E., Vite, Gregory D., Augustine-Rauch, Karen, Fargnoli, Joseph, Borzilleri, Robert M.

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NLRP3 MODULATORS von GAVAI, Ashvinikumar V, DONNELL, Andrew F, GHOSH, Shomir, SIVAPRAKASAM, Prasanna, MARKWALDER, Jay A, SEITZ, Steven P, ZHANG, Yong, ROUSH, William R

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NLRP3 modulators von Gavai, Ashvinikumar V, Markwalder, Jay A, Donnell, Andrew F, Ghosh, Shomir, Seitz, Steven P, Zhang, Yong, Sivaprakasam, Prasanna, Roush, William R

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Nlrp3 modulators von Gavai, Ashvinikumar V, Markwalder, Jay A, Ghosh, Shomir, Donnell, Andrew F, Seitz, Steven P, Zhang, Yong, Sivaprakasam, Prasanna, Roush, William R

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NLRP3 MODULATORS von GAVAI, Ashvinikumar V, DONNELL, Andrew F, GHOSH, Shomir, SIVAPRAKASAM, Prasanna, MARKWALDER, Jay A, SEITZ, Steven P, ZHANG, Yong, ROUSH, William R

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NLRP3 MODULATORS von GAVAI, Ashvinikumar V, DONNELL, Andrew F, GHOSH, Shomir, SIVAPRAKASAM, Prasanna, MARKWALDER, Jay A, SEITZ, Steven P, ZHANG, Yong, ROUSH, William R

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1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS von GAVAI, Ashvinikumar V, DONNELL, Andrew F, TARBY, Christine M, ANDAPPAN MURUGAIAH SUBBAIAH, Murugaiah, HE, Liqi, GANGWAR, Sanjeev, CONG, Qiang, SIVAPRAKASAM, Prasanna, GILL, Patrice, POUDEL, Yam B

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1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS von CHENG, Heng, GAVAI, Ashvinikumar V, DONNELL, Andrew F, TARBY, Christine M, SUBBAIAH, Murugaiah Andappan Murugaiah, GANGWAR, Sanjeev, SIVAPRAKASAM, Prasanna, GILL, Patrice, JOHNSON, Walter L, POUDEL, Yam B

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