Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier von Kim, Jihye, Alejandro, Brian, Hetman, Michal, Hattab, Eyas M, Joiner, Joshua, Schroten, Horst, Ishikawa, Hiroshi, Chung, Dong-Hoon

Volltext

Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay von Adcock, Robert S., Chu, Yong-Kyu, Golden, Jennifer E., Chung, Dong-Hoon

Volltext

Ribosomal stress and Tp53-mediated neuronal apoptosis in response to capsid protein of the Zika virus von Slomnicki, Lukasz P., Chung, Dong-Hoon, Parker, Austin, Hermann, Taylor, Boyd, Nolan L., Hetman, Michal

Volltext

Identification of potent small molecule inhibitors of SARS-CoV-2 entry von Mediouni, Sonia, Mou, Huihui, Otsuka, Yuka, Jablonski, Joseph Anthony, Adcock, Robert Scott, Batra, Lalit, Chung, Dong-Hoon, Rood, Christopher, de Vera, Ian Mitchelle S., Rahaim Jr, Ronald, Ullah, Sultan, Yu, Xuerong, Getmanenko, Yulia A., Kennedy, Nicole M., Wang, Chao, Nguyen, Tu-Trinh, Hull, Mitchell, Chen, Emily, Bannister, Thomas D., Baillargeon, Pierre, Scampavia, Louis, Farzan, Michael, Valente, Susana T., Spicer, Timothy P.

Volltext

Inflammasome-Independent Leukotriene B4 Production Drives Crystalline Silica–Induced Sterile Inflammation von Hegde, Bindu, Bodduluri, Sobha R., Satpathy, Shuchismita R., Alghsham, Ruqaih S., Jala, Venkatakrishna R., Uriarte, Silvia M., Chung, Dong-Hoon, Lawrenz, Matthew B., Haribabu, Bodduluri

Volltext

The Murine Model for Hantaan Virus-Induced Lethal Disease Shows Two Distinct Paths in Viral Evolutionary Trajectory with and without Ribavirin Treatment von Chung, Dong-Hoon, Vaestermark, Aake, Camp, Jeremy V, McAllister, Ryan, Remold, Susanna K, Chu, Yong-Kyu, Bruder, Carl, Jonsson, Colleen B

Volltext

Phenotypic differences in virulence and immune response in closely related clinical isolates of influenza A 2009 H1N1 pandemic viruses in mice von Camp, Jeremy V, Chu, Yong-Kyu, Chung, Dong-Hoon, McAllister, Ryan C, Adcock, Robert S, Gerlach, Rachael L, Wiemken, Timothy L, Peyrani, Paula, Ramirez, Julio A, Summersgill, James T, Jonsson, Colleen B

Volltext

Dynein-Dependent Transport of the Hantaan Virus Nucleocapsid Protein to the Endoplasmic Reticulum-Golgi Intermediate Compartment von RAMANATHAN, Harish N, CHUNG, Dong-Hoon, PLANE, Steven J, SZTUL, Elizabeth, CHU, Yong-Kyu, GUTTIERI, Mary C, MCDOWELL, Michael, ALI, Georgia, JONSSON, Colleen B

Volltext

Ribavirin Reveals a Lethal Threshold of Allowable Mutation Frequency for Hantaan Virus von CHUNG, Dong-Hoon, YANJIE SUN, PARKER, William B, ARTERBURN, Jeffrey B, BARTOLUCCI, Al, JONSSON, Colleen B

Volltext

Activity of Ribavirin against Hantaan Virus Correlates with Production of Ribavirin-5′-Triphosphate, Not with Inhibition of IMP Dehydrogenase von Sun, Yanjie, Chung, Dong-Hoon, Chu, Yong-Kyu, Jonsson, Colleen B, Parker, William B

Volltext

Inflammasome-Independent Leukotriene B 4 Production Drives Crystalline Silica-Induced Sterile Inflammation von Hegde, Bindu, Bodduluri, Sobha R, Satpathy, Shuchismita R, Alghsham, Ruqaih S, Jala, Venkatakrishna R, Uriarte, Silvia M, Chung, Dong-Hoon, Lawrenz, Matthew B, Haribabu, Bodduluri

Volltext

Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State von Chung, Dong-Hoon, Golden, Jennifer E, Adcock, Robert S, Schroeder, Chad E, Chu, Yong-Kyu, Sotsky, Julie B, Cramer, Daniel E, Chilton, Paula M, Song, Chisu, Anantpadma, Manu, Davey, Robert A, Prodhan, Aminul I, Yin, Xinmin, Zhang, Xiang

Volltext

Efficacy of a ML336 derivative against Venezuelan and eastern equine encephalitis viruses von Jonsson, Colleen B., Cao, Xufeng, Lee, Jasper, Gabbard, Jon D., Chu, Yong-Kyu, Fitzpatrick, Elizabeth A., Julander, Justin, Chung, Dong-Hoon, Stabenow, Jennifer, Golden, Jennifer E.

Volltext

Synthesis of 1-β- d-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus von Chung, Dong-Hoon, Kumarapperuma, Sidath C., Sun, Yanjie, Li, Qianjun, Chu, Yong-Kyu, Arterburn, Jeffrey B., Parker, William B., Smith, Jeffrey, Spik, Kristin, Ramanathan, Harish N., Schmaljohn, Connie S., Jonsson, Colleen B.

Volltext

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus von Chung, Dong-Hoon, Moore, Blake P, Matharu, Daljit S, Golden, Jennifer E, Maddox, Clinton, Rasmussen, Lynn, Sosa, Melinda I, Ananthan, Subramaniam, White, E Lucile, Jia, Fuli, Jonsson, Colleen B, Severson, William E

Volltext

High-Throughput Screening of a 100,000-Compound Library for Inhibitors of Influenza A Virus (H3N2) von Severson, William E., McDowell, Michael, Ananthan, Subramaniam, Chung, Dong-Hoon, Rasmussen, Lynn, Sosa, Melinda I., White, E. Lucile, Noah, James, Jonsson, Colleen B.

Volltext

Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine von Chung, Dong-Hoon, Strouse, J Jacob, Sun, Yanjie, Arterburn, Jeffrey B, Parker, William B, Jonsson, Colleen B

Volltext

HTS-driven discovery of new chemotypes with West Nile Virus inhibitory activity von Chung, Dong Hoon, Jonsson, Colleen B, Maddox, Clinton, McKellip, Sara N, Moore, Blake P, Heil, Marintha, White, E Lucile, Ananthan, Subramaniam, Li, Qianjun, Feng, Shuang, Rasmussen, Lynn

Volltext

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes von Schreiber, Stuart L., Kotz, Joanne D., Li, Min, Aubé, Jeffrey, Austin, Christopher P., Reed, John C., Rosen, Hugh, White, E. Lucile, Sklar, Larry A., Lindsley, Craig W., Alexander, Benjamin R., Bittker, Joshua A., Clemons, Paul A., de Souza, Andrea, Foley, Michael A., Palmer, Michelle, Shamji, Alykhan F., Wawer, Mathias J., McManus, Owen, Wu, Meng, Zou, Beiyan, Yu, Haibo, Golden, Jennifer E., Schoenen, Frank J., Simeonov, Anton, Jadhav, Ajit, Jackson, Michael R., Pinkerton, Anthony B., Chung, Thomas D.Y., Griffin, Patrick R., Cravatt, Benjamin F., Hodder, Peter S., Roush, William R., Roberts, Edward, Chung, Dong-Hoon, Jonsson, Colleen B., Noah, James W., Severson, William E., Ananthan, Subramaniam, Edwards, Bruce, Oprea, Tudor I., Conn, P. Jeffrey, Hopkins, Corey R., Wood, Michael R., Stauffer, Shaun R., Emmitte, Kyle A., Brady, Linda S., Driscoll, Jamie, Li, Ingrid Y., Loomis, Carson R., Margolis, Ronald N., Michelotti, Enrique, Perry, Mary E., Pillai, Ajay, Yao, Yong

Volltext

The molecular interaction between ML336 and the VEEV non-structural proteins von M. Skidmore, Abdrew, Chung, Dong-Hoon

Volltext