Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-esca... von Iveson, Timothy, Dr, Donehower, Ross C, MD, Davidenko, Irina, MD, Tjulandin, Sergey, Prof, Deptala, Andrzej, MD, Harrison, Mark, MD, Nirni, Somanath, MD, Lakshmaiah, Kuntegowdanahalli, MD, Thomas, Anne, Prof, Jiang, Yizhou, PhD, Zhu, Min, PhD, Tang, Rui, PhD, Anderson, Abraham, PhD, Dubey, Sarita, MD, Oliner, Kelly S, PhD, Loh, Elwyn, MD

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Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases von Karagkounis, Georgios, Torbenson, Michael S., Daniel, Hubert D., Azad, Nilofer S., Diaz, Luis A., Donehower, Ross C., Hirose, Kenzo, Ahuja, Nita, Pawlik, Timothy M., Choti, Michael A.

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Randomized Phase III Multi-Institutional Study of TNFerade Biologic With Fluorouracil and Radiotherapy for Locally Advanced Pancreatic Cancer: Final Results von HERMAN, Joseph M, WILD, Aaron T, SAVAGE, Dionne T, CANTO, Marcia I, KLAPMAN, Jason, REID, Tony, SHAH, Raj J, HOFFE, Sarah E, ROSEMURGY, Alexander, WOLFGANG, Christopher L, LAHERU, Daniel A, HAO WANG, TRAN, Phuoc T, CHANG, Kenneth J, TAYLOR, Gretchen E, DONEHOWER, Ross C, PAWLIK, Timothy M, ZIEGLER, Mark A, HONGYAN CAI

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Phase II Study of Erlotinib (OSI-774) in Patients With Advanced Hepatocellular Cancer von PHILIP, Philip A, MAHONEY, Michelle R, ALLMER, Cristine, THOMAS, James, PITOT, Henry C, KIM, George, DONEHOWER, Ross C, FITCH, Tom, PICUS, Joel, ERIICHMAN, Charles

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Phase II Study of Erlotinib in Patients With Advanced Biliary Cancer von PHILIP, Philip A, MAHONEY, Michelle R, ALLMER, Cristine, THOMAS, James, PITOT, Henry C, KIM, George, DONEHOWER, Ross C, FITCH, Tom, PICUS, Joel, ERLICHMAN, Charles

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A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer von Yarchoan, Mark, Huang, Chiung‐Yu, Zhu, Qingfeng, Ferguson, Anna K., Durham, Jennifer N., Anders, Robert A., Thompson, Elizabeth D., Rozich, Noah S., Thomas, Dwayne L., Nauroth, Julie M., Rodriguez, Christina, Osipov, Arsen, De Jesus‐Acosta, Ana, Le, Dung T., Murphy, Adrian G., Laheru, Daniel, Donehower, Ross C., Jaffee, Elizabeth M., Zheng, Lei, Azad, Nilofer S.

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Phase I Study of ON 01910.Na, a Novel Modulator of the Polo-Like Kinase 1 Pathway, in Adult Patients With Solid Tumors von JIMENO, Antonio, JING LI, MESSERSMITH, Wells A, LAHERU, Daniel, RUDEK, Michelle A, MANIAR, Manoj, HIDALGO, Manuel, BAKER, Sharyn D, DONEHOWER, Ross C

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Adjuvant Concurrent Chemoradiation for Adenocarcinoma of the Distal Common Bile Duct von Hughes, Michael A., M.D., M.S, Frassica, Deborah A., M.D, Yeo, Charles J., M.D, Riall, Taylor S., M.D, Lillemoe, Keith D., M.D, Cameron, John L., M.D, Donehower, Ross C., M.D, Laheru, Daniel A., M.D, Hruban, Ralph H., M.D, Abrams, Ross A., M.D

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Interventions for preventing neuropathy caused by cisplatin and related compounds von Albers, James W, Chaudhry, Vinay, Cavaletti, Guido, Donehower, Ross C, Albers, James W

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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency von Le, Dung T, Uram, Jennifer N, Wang, Hao, Bartlett, Bjarne R, Kemberling, Holly, Eyring, Aleksandra D, Skora, Andrew D, Luber, Brandon S, Azad, Nilofer S, Laheru, Dan, Biedrzycki, Barbara, Donehower, Ross C, Zaheer, Atif, Fisher, George A, Crocenzi, Todd S, Lee, James J, Duffy, Steven M, Goldberg, Richard M, de la Chapelle, Albert, Koshiji, Minori, Bhaijee, Feriyl, Huebner, Thomas, Hruban, Ralph H, Wood, Laura D, Cuka, Nathan, Pardoll, Drew M, Papadopoulos, Nickolas, Kinzler, Kenneth W, Zhou, Shibin, Cornish, Toby C, Taube, Janis M, Anders, Robert A, Eshleman, James R, Vogelstein, Bert, Diaz, Luis A

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A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors von JIANQING LIN, GILBERT, Jill, DONEHOWER, Ross C, CARDUCCI, Michael A, RUDEK, Michelle A, ZWIEBEL, James A, GORE, Steve, JIEMJIT, Anchalee, MING ZHAO, BAKER, Sharyn D, AMBINDER, Richard F, HERMAN, James G

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Interventions for preventing neuropathy caused by cisplatin and related compounds von Albers, James W, Chaudhry, Vinay, Cavaletti, Guido, Donehower, Ross C

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Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer von Le, Dung T, Lutz, Eric, Uram, Jennifer N, Sugar, Elizabeth A, Onners, Beth, Solt, Sara, Zheng, Lei, Diaz, Jr, Luis A, Donehower, Ross C, Jaffee, Elizabeth M, Laheru, Daniel A

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Phase 2 Study of Erlotinib Combined With Adjuvant Chemoradiation and Chemotherapy in Patients With Resectable Pancreatic Cancer von Herman, Joseph M., MD, MSc, Fan, Katherine Y., BS, Wild, Aaron T., BA, Hacker-Prietz, Amy, MS, PA-C, Wood, Laura D., MD, PhD, Blackford, Amanda L., ScM, Ellsworth, Susannah, MD, Zheng, Lei, MD, Le, Dung T., MD, De Jesus-Acosta, Ana, MD, Hidalgo, Manuel, MD, PhD, Donehower, Ross C., MD, Schulick, Richard D., MD, MBA, Edil, Barish H., MD, Choti, Michael A., MD, Hruban, Ralph H., MD, Pawlik, Timothy M., MD, MPH, PhD, Cameron, John L., MD, Laheru, Daniel A., MD, Wolfgang, Christopher L., MD, PhD

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A Phase I Clinical and Pharmacological Evaluation of Sodium Phenylbutyrate on an 120-h Infusion Schedule von CARDUCCI, Michael A, GILBERT, Jill, BOWLING, M. Katherine, NOE, Dennis, EISENBERGER, Mario A, SINIBALDI, Victoria, ZABELINA, Yelena, CHEN, Tian-Ling, GROCHOW, Louise B, DONEHOWER, Ross C

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A Phase I Dose Escalation and Bioavailability Study of Oral Sodium Phenylbutyrate in Patients with Refractory Solid Tumor Malignancies von GILBERT, Jill, BAKER, Sharyn D, BOWLING, M. Katherine, GROCHOW, Louise, FIGG, W. Douglas, ZABELINA, Yelena, DONEHOWER, Ross C, CARDUCCI, Michael A

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Pharmacodynamic-Guided Modified Continuous Reassessment Method–Based, Dose-Finding Study of Rapamycin in Adult Patients With Solid Tumors von Jimeno, Antonio, Rudek, Michelle A, Kulesza, Peter, Ma, Wen Wee, Wheelhouse, Jenna, Howard, Anna, Khan, Yasmin, Zhao, Ming, Jacene, Heather, Messersmith, Wells A, Laheru, Daniel, Donehower, Ross C, Garrett-Mayer, Elizabeth, Baker, Sharyn D, Hidalgo, Manuel

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Correlation of Smad4 Status With Outcomes in Patients Receiving Erlotinib Combined With Adjuvant Chemoradiation and Chemotherapy After Resection for Pancreatic Adenocarcinoma von Herman, Joseph M., MD, MSc, Fan, Katherine Y., BS, Wild, Aaron T., BA, Wood, Laura D., MD, PhD, Blackford, Amanda L., ScM, Donehower, Ross C., MD, Hidalgo, Manuel, MD, PhD, Schulick, Richard D., MD, MBA, Edil, Barish H., MD, Choti, Michael A., MD, Hruban, Ralph H., MD, Pawlik, Timothy M., MD, MPH, PhD, Cameron, John L., MD, Laheru, Daniel A., MD, Iacobuzio-Donahue, Christine A., MD, Wolfgang, Christopher L., MD, PhD

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Impact of Prolonged Infusions of the Putative Differentiating Agent Sodium Phenylbutyrate on Myelodysplastic Syndromes and Acute Myeloid Leukemia von GORE, Steven D, WENG, Li-Jun, BURKS, Kathleen, ZABELENA, Yelena, MILLER, Carole B, FIGG, William D, SUOPING ZHAI, DONEHOWER, Ross C, DOVER, George, GREVER, Michael R, GRIFFIN, Constance, GROCHOW, Louise B, HAWKINS, Anita

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Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer von Azad, Nilofer, Dasari, Arvind, Arcaroli, John, Taylor, Gretchen E., Laheru, Daniel A., Carducci, Michael A., McManus, Martine, Quackenbush, Kevin, Wright, John J., Hidalgo, Manuel, Diaz, Luis A., Donehower, Ross C., Zhao, Ming, Rudek, Michelle A., Messersmith, Wells A.

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