Pharmacotherapy in Coronavirus Disease 2019 and Risk of Secondary Infections: A Single-Center Case Series and Narrative Review von Behal, Michael, Barlow, Brooke, Mefford, Breanne, Thompson Bastin, Melissa L., Donaldson, J. Chris, Laine, Melanie, Bissell, Brittany D.

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To Block or Not: Updates in Neuromuscular Blockade in Acute Respiratory Distress Syndrome von Mefford, Breanne, Donaldson, J. Chris, Bissell, Brittany D.

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Comment: Low-Dose Tocilizumab With High-Dose Corticosteroids in Patients Hospitalized for COVID-19 Hypoxic Respiratory Failure Improves Mortality Without Increased Infection Risk von Bissell, Brittany D., Mefford, Breanne, Donaldson, J. Chris

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The immunomodulatory effects of opioids and implications for intensive care unit populations von Mefford, Breanne, Donaldson, J. Chris, Bissell, Brittany D.

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Effect modification of dosing strategy (AUC or trough) on AKI associated with vancomycin in combination with piperacillin/tazobactam or cefepime and meropenem von Mefford, Breanne, Wallace, Katie L, Donaldson, J Chris, Bissell Turpin, Brittany D, Sen, Parijat, Schadler, Aric D, Liu, Lucas J, Thompson Bastin, Melissa L

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A narrative review of pharmacologic de-resuscitation in the critically ill von Bissell, Brittany D., Donaldson, J. Chris, Morris, Peter E., Neyra, Javier A.

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1093: IMPACT OF PRONING ON PARALYZED PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME von Wiegand, Alexandra, Bastin, Melissa Thompson, Cole, Adam, Schadler, Aric, Gray, Tori, Donaldson, J. Chris, Kressin, Christian, Bonnet, Elizabeth, Mefford, Breanne

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Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis von Mells, George F, Floyd, James A B, Morley, Katherine I, Cordell, Heather J, Franklin, Christopher S, Shin, So-Youn, Heneghan, Michael A, Neuberger, James M, Donaldson, Peter T, Day, Darren B, Ducker, Samantha J, Muriithi, Agnes W, Wheater, Elizabeth F, Hammond, Christopher J, Dawwas, Muhammad F, Jones, David E, Peltonen, Leena, Alexander, Graeme J, Sandford, Richard N, Anderson, Carl A

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Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes von Cho, Wan-Seob, Duffin, Rodger, Howie, Sarah E M, Scotton, Chris J, Wallace, William A H, Macnee, William, Bradley, Mark, Megson, Ian L, Donaldson, Ken

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Green Plants in the Red: A Baseline Global Assessment for the IUCN Sampled Red List Index for Plants von Brummitt, Neil A, Bachman, Steven P, Griffiths-Lee, Janine, Lutz, Maiko, Moat, Justin F, Farjon, Aljos, Donaldson, John S, Hilton-Taylor, Craig, Meagher, Thomas R, Albuquerque, Sara, Aletrari, Elina, Andrews, A Kei, Atchison, Guy, Baloch, Elisabeth, Barlozzini, Barbara, Brunazzi, Alice, Carretero, Julia, Celesti, Marco, Chadburn, Helen, Cianfoni, Eduardo, Cockel, Chris, Coldwell, Vanessa, Concetti, Benedetta, Contu, Sara, Crook, Vicki, Dyson, Philippa, Gardiner, Lauren, Ghanim, Nadia, Greene, Hannah, Groom, Alice, Harker, Ruth, Hopkins, Della, Khela, Sonia, Lakeman-Fraser, Poppy, Lindon, Heather, Lockwood, Helen, Loftus, Christine, Lombrici, Debora, Lopez-Poveda, Lucia, Lyon, James, Malcolm-Tompkins, Patricia, McGregor, Kirsty, Moreno, Laura, Murray, Linda, Nazar, Keara, Power, Emily, Quiton Tuijtelaars, Mireya, Salter, Ruth, Segrott, Robert, Thacker, Hannah, Thomas, Leighton J, Tingvoll, Sarah, Watkinson, Gemma, Wojtaszekova, Katerina, Nic Lughadha, Eimear M

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Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy von Oltean, Sebastian, Qiu, Yan, Ferguson, Joanne K, Stevens, Megan, Neal, Chris, Russell, Amy, Kaura, Amit, Arkill, Kenton P, Harris, Kirstie, Symonds, Clare, Lacey, Katja, Wijeyaratne, Lihini, Gammons, Melissa, Wylie, Emma, Hulse, Richard P, Alsop, Chloe, Cope, George, Damodaran, Gopinath, Betteridge, Kai B, Ramnath, Raina, Satchell, Simon C, Foster, Rebecca R, Ballmer-Hofer, Kurt, Donaldson, Lucy F, Barratt, Jonathan, Baelde, Hans J, Harper, Steven J, Bates, David O, Salmon, Andrew H J

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Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial von Beard, David J, Rees, Jonathan L, Cook, Jonathan A, Rombach, Ines, Cooper, Cushla, Merritt, Naomi, Shirkey, Beverly A, Donovan, Jenny L, Gwilym, Stephen, Savulescu, Julian, Moser, Jane, Gray, Alastair, Jepson, Marcus, Tracey, Irene, Judge, Andrew, Wartolowska, Karolina, Carr, Andrew J, Ahrens, Philip, Baldwick, Cheryl, Brinsden, Mark, Brownlow, Harry, Burton, David, Butt, Muhammad Sohail, Carr, Andrew, Charalambous, Charalambos P, Conboy, Veronica, Dennell, Lucy, Donaldson, Oliver, Drew, Steven, Dwyer, Amitabh, Gidden, David, Hallam, Peter, Kalogrianitis, Socrates, Kelly, Cormac, Kulkarni, Rohit, Matthews, Tim, McBirnie, Julie, Patel, Vipul, Peach, Chris, Roberts, Chris, Robinson, David, Rosell, Philip, Rossouw, Dan, Senior, Colin, Singh, Bijayendra, Sjolin, Soren, Taylor, Geoffrey, Venkateswaran, Balachandran, Woods, David

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Empagliflozin in Patients with Chronic Kidney Disease von Herrington, William G, Staplin, Natalie, Wanner, Christoph, Green, Jennifer B, Hauske, Sibylle J, Emberson, Jonathan R, Preiss, David, Judge, Parminder, Mayne, Kaitlin J, Ng, Sarah Y A, Sammons, Emily, Zhu, Doreen, Hill, Michael, Stevens, Will, Wallendszus, Karl, Brenner, Susanne, Cheung, Alfred K, Liu, Zhi-Hong, Li, Jing, Hooi, Lai Seong, Liu, Wen, Kadowaki, Takashi, Nangaku, Masaomi, Levin, Adeera, Cherney, David, Maggioni, Aldo P, Pontremoli, Roberto, Deo, Rajat, Goto, Shinya, Rossello, Xavier, Tuttle, Katherine R, Steubl, Dominik, Petrini, Michaela, Massey, Dan, Eilbracht, Jens, Brueckmann, Martina, Landray, Martin J, Baigent, Colin, Haynes, Richard

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Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE von MAVADDAT, Nasim, PEOCK, Susan, DAVIDSON, Rosemarie, ECCLES, Diana, COLE, Trevor, COOK, Jackie, BREWER, Carole, TISCHKOWITZ, Marc, DOUGLAS, Fiona, HODGSON, Shirley, WALKER, Lisa, PORTEOUS, Mary E, FROST, Debra, MORRISON, Patrick J, SIDE, Lucy E, KENNEDY, M. John, HOUGHTON, Catherine, DONALDSON, Alan, ROGERS, Mark T, DORKINS, Huw, MIEDZYBRODZKA, Zosia, GREGORY, Helen, EASON, Jacqueline, ELLIS, Steve, BARWELL, Julian, MCCANN, Emma, MURRAY, Alex, ANTONIOU, Antonis C, EASTON, Douglas F, PLATTE, Radka, FINEBERG, Elena, EVANS, D. Gareth, IZATT, Louise, EELES, Rosalind A, ADLARD, Julian

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Prevalence and architecture of de novo mutations in developmental disorders von McRae, Jeremy F, Clayton, Stephen, Mason, Laura E, Tivey, Adrian R, Ahmed, Munaza, Awada, Jana, Balasubramanian, Meena, Banka, Siddharth, Bennett, Chris, Bernhard, Birgitta, Bevan, A. Paul, Blair, Edward, Blyth, Moira, Burn, John, Castle, Bruce, Clasper, Susan, Collins, Amanda, Collinson, Morag N, Dabir, Tabib, Davidson, Rosemarie, Davies, Sally, Dean, John, Donnai, Dian, Ellard, Sian, Ellis, Ian, Everest, Sarah, Foulds, Nicola, Fryer, Alan, Gaunt, Lorraine, Goudie, David, Gray, Emma, Greene, Philip, Gribble, Susan, Henderson, Alex, Hildyard, Lucy, Holden, Simon, Holder, Muriel, Ingram, Stuart, Jackson, Andrew, Kaemba, Beckie, Kazembe, Sandra, Kinning, Esther, Kraus, Alison, Kumar, V. K. Ajith, Lachlan, Katherine, Lam, Wayne, Lim, Derek, Longman, Cheryl, Lynch, Sally A, Maher, Eddy, Maye, Una, McKay, Kirsten, McWilliam, Catherine, Metcalfe, Kay, Morgan, Sian, Murday, Victoria, Murphy, Helen, Nemeth, Andrea, Nevitt, Louise, Newbury-Ecob, Ruth, Park, Soo-Mi, Paterson, Joan, Payne, Stewart, Perrett, Daniel, Pratt, Norman, Quarrell, Oliver, Randall, Josh, Rankin, Julia, Raymond, Lucy, Robert, Leema, Roberts, Paul, Saggar, Anand, Samant, Shalaka, Sampson, Julian, Sandford, Richard, Selby, Ann, Sequeira, Cheryl, Shearing, Emma, Smith, Audrey, Smith, Kath, Splitt, Miranda, Suri, Mohnish, Sutton, Vivienne, Tatton-Brown, Kate, Temple, I. Karen, Turner, Claire, Varghese, Vinod, Vasudevan, Pradeep, Vogt, Julie, Wakeling, Emma, Wilcox, Sarah, Williams, Denise, Williams, Nicola, Wilson, Louise, Wright, Michael, Yates, Laura, Yau, Michael, Wright, Caroline F, FitzPatrick, David R, Barrett, Jeffrey C

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Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) von MAVADDAT, Nasim, BARROWDALE, Daniel, MULLIGAN, Anna Marie, COUCH, Fergus J, ENGEL, Christoph, MCGUFFOG, Lesley, HEALER, Sue, SINILNIKOVA, Olga M, SOUTHEY, Melissa C, TERRY, Mary Beth, GOLDGAR, David, O'MALLEY, Frances, ANDRULIS, Irene L, JOHN, Esther M, JANAVICIUS, Ramunas, TIHOMIROVA, Laima, HANSEN, Thomas V. O, NIELSEN, Finn C, OSORIO, Ana, STAVROPOULOU, Alexandra, BENITEZ, Javier, MANOUKIAN, Siranoush, PEISSEL, Bernard, DOMCHEK, Susan M, BARILE, Monica, VOLORIO, Sara, PASIN, Barbara, DOLCETTI, Riccardo, PUTIGNANO, Anna Laura, OTTINI, Laura, RADICE, Paolo, HAMANN, Ute, RASHID, Muhammad U, HOGERVORST, Frans B, ECCLES, Diana, KRIEGE, Mieke, VAN DER LUIJT, Rob B, HEBON, PEOCK, Susan, FROST, Debra, GARETH EVANS, D, BREWER, Carole, WALKER, Lisa, ROGERS, Mark T, SIDE, Lucy E, NEVANLINNA, Heli, HOUGHTON, Catherine, EMBRACE, WEAVER, Joellen, GODWIN, Andrew K, SCHMUTZLER, Rita K, WAPPENSCHMIDT, Barbara, MEINDL, Alfons, KAST, Karin, RAMUS, Susan J, SPURDLE, Amanda, ROBSON, Mark, SHERMAN, Mark

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Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis von Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M, Donaldson, Peter T, Bathgate, Andrew J, Burroughs, Andrew, Davies, Mervyn H, Jones, David E, Alexander, Graeme J, Barrett, Jeffrey C, Sandford, Richard N, Anderson, Carl A

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Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer von Ruark, Elise, Snape, Katie, Humburg, Peter, Loveday, Chey, Bajrami, Ilirjana, Brough, Rachel, Rodrigues, Daniel Nava, Renwick, Anthony, Seal, Sheila, Ramsay, Emma, Duarte, Silvana Del Vecchio, Rivas, Manuel A., Warren-Perry, Margaret, Zachariou, Anna, Campion-Flora, Adriana, Hanks, Sandra, Murray, Anne, Pour, Naser Ansari, Douglas, Jenny, Gregory, Lorna, Rimmer, Andrew, Walker, Neil M., Yang, Tsun-Po, Adlard, Julian W., Barwell, Julian, Berg, Jonathan, Brady, Angela F., Brewer, Carole, Brice, Glen, Chapman, Cyril, Cook, Jackie, Davidson, Rosemarie, Donaldson, Alan, Douglas, Fiona, Eccles, Diana, Evans, D. Gareth, Greenhalgh, Lynn, Henderson, Alex, Izatt, Louise, Kumar, Ajith, Lalloo, Fiona, Miedzybrodzka, Zosia, Morrison, Patrick J., Paterson, Joan, Porteous, Mary, Rogers, Mark T., Shanley, Susan, Walker, Lisa, Gore, Martin, Houlston, Richard, Brown, Matthew A., Caufield, Mark J., Deloukas, Panagiotis, McCarthy, Mark I., Todd, John A., Turnbull, Clare, Reis-Filho, Jorge S., Ashworth, Alan, Antoniou, Antonis C., Lord, Christopher J., Donnelly, Peter, Rahman, Nazneen

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SOX11 variants cause a neurodevelopmental disorder with infrequent ocular malformations and hypogonadotropic hypogonadism and with distinct DNA methylation profile von Al-Jawahiri, Reem, Foroutan, Aidin, McConkey, Haley, Levy, Michael, Haghshenas, Sadegheh, Rooney, Kathleen, Turner, Jasmin, Shears, Debbie, Holder, Muriel, Lefroy, Henrietta, Castle, Bruce, Reis, Linda M., Semina, Elena V., Nickerson, Deborah, Bamshad, Michael, Leal, Suzanne, Lachlan, Katherine, Chandler, Kate, Clayton-Smith, Jill, Hug, Franziska Phan, Pitteloud, Nelly, Bartoloni, Lucia, Hoffjan, Sabine, Park, Soo-Mi, Thankamony, Ajay, Lees, Melissa, Wakeling, Emma, Naik, Swati, Hanker, Britta, Girisha, Katta M., Agolini, Emanuele, Giuseppe, Zampino, Alban, Ziegler, Tessarech, Marine, Keren, Boris, Afenjar, Alexandra, Zweier, Christiane, Smol, Thomas, Nobuhiko, Okamoto, Sekiguchi, Futoshi, Tsuchida, Naomi, Matsumoto, Naomichi, Kou, Ikuyo, Yonezawa, Yoshiro, Ikegawa, Shiro, Callewaert, Bert, Ambrose, John C., Arumugam, Prabhu, Bleda, Marta, Boardman-Pretty, Freya, Boustred, Christopher R., Brittain, Helen, Caulfield, Mark J., Chan, Georgia C., Fowler, Tom, Giess, Adam, Hamblin, Angela, Henderson, Shirley, Hubbard, Tim J.P., Jones, Louise J., Kasperaviciute, Dalia, Kayikci, Melis, Kousathanas, Athanasios, Lahnstein, Lea, Leigh, Sarah E.A., Leong, Ivonne U.S., Lopez, Javier F., FionaMaleady-Crowe, McEntagart, Meriel, Minneci, Federico, Moutsianas, Loukas, Mueller, Michael, Murugaesu, Nirupa, Need, Anna C., Odhams, Chris A., Patch, Christine, Perez-Gil, Daniel, Pullinger, John, Rendon, Augusto, TimRogers, Savage, Kevin, Sawant, Kushmita, Scott, Richard H., Siddiq, Afshan, Sieghart, Alexander, Smith, Samuel C., Sosinsky, Alona, Stuckey, Alexander, Tanguy, Mélanie, Taylor Tavares, Ana Lisa, Thomas, Ellen R.A., Thompson, Simon R., Tucci, Arianna, Williams, Eleanor, Kleinendorst, Lotte, Donaldson, Alan, Alders, Marielle, De Paepe, Anne, Sadikovic, Bekim, McNeill, Alisdair

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Effects of Empagliflozin on Fluid Overload, Weight, and Blood Pressure in CKD von Mayne, Kaitlin J, Staplin, Natalie, Keane, David F, Wanner, Christoph, Brenner, Susanne, Cejka, Vladimir, Stegbauer, Johannes, Judge, Parminder K, Preiss, David, Emberson, Jonathan, Trinca, Daniele, Dayanandan, Rejive, Lee, Ryonfa, Nolan, John, Omata, Akiko, Green, Jennifer B, Cherney, David Z I, Hooi, Lai Seong, Pontremoli, Roberto, Tuttle, Katherine R, Lees, Jennifer S, Mark, Patrick B, Davies, Simon J, Hauske, Sibylle J, Steubl, Dominik, Brückmann, Martina, Landray, Martin J, Baigent, Colin, Haynes, Richard, Herrington, William G

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