Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 do... von Longo, Nicola, MD, Harding, Cary O, MD, Burton, Barbara K, MD, Grange, Dorothy K, MD, Vockley, Jerry, MD, Wasserstein, Melissa, MD, Rice, Gregory M, MD, Dorenbaum, Alejandro, MD, Neuenburg, Jutta K, MD, Musson, Donald G, PhD, Gu, Zhonghua, PhD, Sile, Saba, MD

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Immunogenicity of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients With Morquio A Syndrome: Results From MOR-004, a Phase III Trial von Schweighardt, Becky, PhD, Tompkins, Troy, BS, Lau, Kelly, MS, Jesaitis, Lynne, PhD, Qi, Yulan, PhD, Musson, Donald G., PhD, Farmer, Pamela, MD, Haller, Christine, MD, Shaywitz, Adam J., MD, PhD, Yang, Ke, PhD, O’Neill, Charles A., PhD

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Nonclinical evaluation of CNS-administered TPP1 enzyme replacement in canine CLN2 neuronal ceroid lipofuscinosis von Vuillemenot, Brian R., Kennedy, Derek, Cooper, Jonathan D., Wong, Andrew M.S., Sri, Sarmi, Doeleman, Thom, Katz, Martin L., Coates, Joan R., Johnson, Gayle C., Reed, Randall P., Adams, Eric L., Butt, Mark T., Musson, Donald G., Henshaw, Joshua, Keve, Steve, Cahayag, Rhea, Tsuruda, Laurie S., O'Neill, Charles A.

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Acetylator Status Impacts Amifampridine Phosphate (Firdapse™) Pharmacokinetics and Exposure to a Greater Extent Than Renal Function von Haroldsen, Peter E., PhD, Sisic, Zlatko, MD, Datt, Joe, MD, Musson, Donald G., PhD, Ingenito, Gary, MD, PhD

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Effects of Food Intake on the Relative Bioavailability of Amifampridine Phosphate Salt in Healthy Adults von Haroldsen, Peter E., PhD, Musson, Donald G., PhD, Hanson, Boyd, PhD, Quartel, Adrian, MD, O’Neill, Charles A., PhD

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Investigation of high-throughput ultrafiltration for the determination of an unbound compound in human plasma using liquid chromatography and tandem mass spectrometry with electros... von Zhang, Jin, Musson, Donald G.

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Strategies on efficient method development of on-line extraction assays for determination of MK-0974 in human plasma and urine using turbulent-flow chromatography and tandem mass s... von Xu, Yang, Willson, Kenneth J., Musson, Donald G.

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Reversed-phase chiral liquid chromatography on polysaccharide-based stationary phase coupled with tandem mass spectrometry for simultaneous determination of four stereoisomers of M... von Xu, Yang, Musson, Donald G.

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Application of a novel ultra-low elution volume 96-well solid-phase extraction method to the LC/MS/MS determination of simvastatin and simvastatin acid in human plasma von Yang, Amy Y., Sun, Li, Musson, Donald G., Zhao, Jamie J.

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Relative bioavailability of sapropterin from intact and dissolved sapropterin dihydrochloride tablets and the effects of food: A randomized, open-label, crossover study in healthy... von Musson, Donald G., PhD, Kramer, William G., PhD, Foehr, Erik D., PhD, Bieberdorf, Frederick A., MD, Hornfeldt, Carl S., PhD, Kim, Sun Sook, MS, Dorenbaum, Alex, MD

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Genetic variation in aryl N‐acetyltransferase results in significant differences in the pharmacokinetic and safety profiles of amifampridine (3,4‐diaminopyridine) phosphate von Haroldsen, Peter E., Garovoy, Marvin R., Musson, Donald G., Zhou, Huiyu, Tsuruda, Laurie, Hanson, Boyd, O'Neill, Charles A.

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High turbulence liquid chromatography online extraction and tandem mass spectrometry for the simultaneous determination of suberoylanilide hydroxamic acid and its two metabolites i... von Du, Lihong, Musson, Donald G., Wang, Amy Qiu

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Pharmacokinetic and Pharmacodynamic Evaluation of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients with Morquio A Syndrome von Qi, Yulan, Musson, Donald G., Schweighardt, Becky, Tompkins, Troy, Jesaitis, Lynne, Shaywitz, Adam J., Yang, Ke, O’Neill, Charles A.

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A new approach for evaluating carryover and its influence on quantitation in high-performance liquid chromatography and tandem mass spectrometry assay von Zeng, Wei, Musson, Donald G., Fisher, Alison L., Wang, Amy Qiu

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Elimination of diastereomer interference to determine Telcagepant (MK-0974) in human plasma using on-line turbulent-flow technology and off-line solid-phase extraction coupled with... von Xu, Yang, Willson, Kenneth J., Anderson, Melanie D.G., Musson, Donald G., Miller-Stein, Cynthia M., Woolf, Eric J.

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Maternal phenylketonuria syndrome: studies in mice suggest a potential approach to a continuing problem von Zeile, William L, McCune, Helen C, Musson, Donald G, O'Donnell, Brian, O'Neill, Charles A, Tsuruda, Laurie S, Zori, Roberto T, Laipis, Philip J

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A Prospective Population Pharmacokinetic Analysis of Sapropterin Dihydrochloride in Infants and Young Children with Phenylketonuria von Qi, Yulan, Mould, Diane R., Zhou, Huiyu, Merilainen, Markus, Musson, Donald G.

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Concerns in the development of an assay for determination of a highly conjugated adsorption-prone compound in human urine von YANG XU, LIHONG DU, ROSE, Mark J, IRONG FU, WOOLF, Eric J, MUSSON, Donald G

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Recombinant human tripeptidyl peptidase-1 infusion to the monkey CNS: Safety, pharmacokinetics, and distribution von Vuillemenot, Brian R., Kennedy, Derek, Reed, Randall P., Boyd, Robert B., Butt, Mark T., Musson, Donald G., Keve, Steve, Cahayag, Rhea, Tsuruda, Laurie S., O'Neill, Charles A.

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Assay methodology for the quantitation of unbound ertapenem, a new carbapenem antibiotic, in human plasma von Musson, Donald G, Birk, Kimberly L, Kitchen, Chester J, Zhang, Jin, Hsieh, John Y.K, Fang, Wei, Majumdar, Anup K, Rogers, John D

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