Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors von Higa, Kelly C, Goodspeed, Andrew, Chavez, James S, De Dominici, Marco, Danis, Etienne, Zaberezhnyy, Vadym, Rabe, Jennifer L, Tenen, Daniel G, Pietras, Eric M, DeGregori, James

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Targeting CDK6 and BCL2 Exploits the "MYB Addiction" of Ph + Acute Lymphoblastic Leukemia von De Dominici, Marco, Porazzi, Patrizia, Soliera, Angela Rachele, Mariani, Samanta A, Addya, Sankar, Fortina, Paolo, Peterson, Luke F, Spinelli, Orietta, Rambaldi, Alessandro, Martinelli, Giovanni, Ferrari, Anna, Iacobucci, Ilaria, Calabretta, Bruno

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Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells von Spagnuolo, Manuela, Regazzo, Giulia, De Dominici, Marco, Sacconi, Andrea, Pelosi, Andrea, Korita, Etleva, Marchesi, Francesco, Pisani, Francesco, Magenta, Alessandra, Lulli, Valentina, Cordone, Iole, Mengarelli, Andrea, Strano, Sabrina, Blandino, Giovanni, Rizzo, Maria G, Calabretta, Bruno

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Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification von Petruk, Svetlana, Mariani, Samanta A., De Dominici, Marco, Porazzi, Patrizia, Minieri, Valentina, Cai, Jingli, Iacovitti, Lorraine, Flomenberg, Neal, Calabretta, Bruno, Mazo, Alexander

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Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb von D'Aguanno, Simona, Valentini, Elisabetta, Tupone, Maria Grazia, Desideri, Marianna, Di Martile, Marta, Spagnuolo, Manuela, Buglioni, Simonetta, Ercolani, Cristiana, Falcone, Italia, De Dominici, Marco, Milella, Michele, Rizzo, Maria Giulia, Calabretta, Bruno, Cota, Carlo, Anichini, Andrea, Trisciuoglio, Daniela, Del Bufalo, Donatella

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Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2 von Riva, Beatrice, De Dominici, Marco, Gnemmi, Ilaria, Mariani, Samanta A, Minassi, Alberto, Minieri, Valentina, Salomoni, Paolo, Canonico, Pier Luigi, Genazzani, Armando A, Calabretta, Bruno, Condorelli, Fabrizio

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Our ancestry dictates clonal architecture and skin cancer susceptibility von De Dominici, Marco, DeGregori, James

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Shedding Light on Mutant Clonal Dynamics and Cancer Risk in the Skin von De Dominici, Marco, DeGregori, James

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Exploring Aging Dependent Adaptations of Splicing Factor Mutations in Clonal Hematopoiesis von Hoag, Bridget, De Dominici, Marco, Alberti, Michael O., DeGregori, James

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Dnmt3a-Mutant Hematopoietic Stem Cell Rewire IFNγ Signaling to Gain Clonal Advantage von De Dominici, Marco, DeGregori, James

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CHIP: a clonal odyssey of the bone marrow niche von Schleicher, Wolfgang E, Hoag, Bridget, De Dominici, Marco, DeGregori, James, Pietras, Eric M

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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs von De Dominici, Marco, Porazzi, Patrizia, Xiao, Youcai, Chao, Allen, Tang, Hsin-Yao, Kumar, Gaurav, Fortina, Paolo, Spinelli, Orietta, Rambaldi, Alessandro, Peterson, Luke F., Petruk, Svetlana, Barletta, Camilla, Mazo, Alexander, Cingolani, Gino, Salvino, Joseph M., Calabretta, Bruno

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Targeting the CDK6 Dependence of Ph+ Acute Lymphoblastic Leukemia von Porazzi, Patrizia, De Dominici, Marco, Salvino, Joseph, Calabretta, Bruno

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Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression von Porazzi, Patrizia, Petruk, Svetlana, Pagliaroli, Luca, De Dominici, Marco, Deming, 2nd, David, Puccetti, Matthew V, Kushinsky, Saul, Kumar, Gaurav, Minieri, Valentina, Barbieri, Elisa, Deliard, Sandra, Grande, Alexis, Trizzino, Marco, Gardini, Alessandro, Canaani, Eli, Palmisiano, Neil, Porcu, Pierluigi, Ertel, Adam, Fortina, Paolo, Eischen, Christine M, Mazo, Alexander, Calabretta, Bruno

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Abstract PR001: Dissecting the role of aging and inflammation on clonal hematopoiesis von Dominici, Marco De, Menzel, Johannes, DeGregori, James V.

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A phase I study of the combination of palbociclib and dexamethasone for the treatment of relapsed or refractory B-cell acute lymphoblastic leukemia von Wilde, Lindsay, Porazzi, Patrizia, Trotta, Rossana, De Dominici, Marco, Palmisiano, Neil, Keiffer, Gina, Rancani, Kaitlin, Yingling, Kathryn, Calabretta, Bruno, Kasner, Margaret

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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia von Minieri, Valentina, De Dominici, Marco, Porazzi, Patrizia, Mariani, Samanta A, Spinelli, Orietta, Rambaldi, Alessandro, Peterson, Luke F, Porcu, Pierluigi, Nevalainen, Marja T, Calabretta, Bruno

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Targeting chemotherapy to de-condensed H3K27me3-marked chromatin of AML cells enhances leukemia suppression von Porazzi, Patrizia, Petruk, Svetlana, Pagliaroli, Luca, De Dominici, Marco, Deming, David, Puccetti, Matthew V., Kushinsky, Saul, Kumar, Gaurav, Minieri, Valentina, Barbieri, Elisa, Deliard, Sandra, Grande, Alexis, Trizzino, Marco, Gardini, Alessandro, Canaani, Eli, Palmisiano, Neil, Porcu, Pierluigi, Ertel, Adam, Fortina, Paolo, Eischen, Christine M., Mazo, Alexander, Calabretta, Bruno

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CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia von Mariani, S A, Minieri, V, De Dominici, M, Iacobucci, I, Peterson, L F, Calabretta, B

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Targeting the STAT5 pathway in Ph+ acute lymphoblastic leukemia von Minieri, Valentina, De Dominici, Marco, Nevalainen, Marja T, Calabretta, Bruno

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