The transition to dolutegravir and other new antiretrovirals in low-income and middle-income countries: what are the issues? von Vitoria, Marco, Hill, Andrew, Ford, Nathan, Doherty, Meg, Clayden, Polly, Venter, Francois, Ripin, David, Flexner, Charles, Domanico, Paul L

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A year-long extended release nanoformulated cabotegravir prodrug von Kulkarni, Tanmay A., Bade, Aditya N., Sillman, Brady, Shetty, Bhagya Laxmi Dyavar, Wojtkiewicz, Melinda S., Gautam, Nagsen, Hilaire, James R., Sravanam, Sruthi, Szlachetka, Adam, Lamberty, Benjamin G., Morsey, Brenda M., Fox, Howard S., Alnouti, Yazen, McMillan, JoEllyn M., Mosley, R. Lee, Meza, Jane, Domanico, Paul L., Yue, Tai-Yuen, Moore, Gary, Edagwa, Benson J., Gendelman, Howard E.

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Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate von Watkins, Melynda E., Wring, Steve, Randolph, Ryan, Park, Seonghee, Powell, Kendall, Lutz, Lissa, Nowakowski, Michelle, Ramabhadran, Ram, Domanico, Paul L.

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In vitro screening for molecules that affect virus capsid assembly (and other protein association reactions) von Zlotnick, Adam, Lee, Angela, Bourne, Christina R, Johnson, Jennifer M, Domanico, Paul L, Stray, Stephen J

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Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate von Moss, Darren M, Domanico, Paul, Watkins, Melynda, Park, Seonghee, Randolph, Ryan, Wring, Steve, Rajoli, Rajith Kumar Reddy, Hobson, James, Rannard, Steve, Siccardi, Marco, Owen, Andrew

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What babies need: accelerating access to current and novel antiretroviral drugs in neonates through pharmacokinetic studies von Jacobs, Tom G, Schouwenburg, Stef, Penazzato, Martina, Archary, Moherndran, Ruel, Theodore D, van den Anker, John, Burger, David M, Cressey, Tim R, Abrams, Elaine J, Lyall, Hermione, Bekker, Adrie, Colbers, Angela

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Design and Synthesis of Conformationally Constrained Analogs of 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as Potent Inhibitors of cAMP-Specific Phosphodiesterase von Brackeen, Marcus F, Stafford, Jeffrey A, Cowan, David J, Brown, Peter J, Domanico, Paul L, Feldman, Paul L, Rose, Dudley, Strickland, Alan B, Veal, James M, Verghese, Margrith

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Pharmacologists get a bigger and better tool box von Kenakin, Terry, Domanico, Paul

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Association and metabolism of exogenously-derived lysophosphatidylcholine by cultured mammalian cells: kinetics and mechanisms von Besterman, Jeffrey M, Domanico, Paul L

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Phosphodiesterase Type IV Inhibition. Structure-Activity Relationships of 1,3-Disubstituted Pyrrolidines von Feldman, Paul L, Brackeen, Marcus F, Cowan, David J, Marron, Brian E, Schoenen, Frank J, Stafford, Jeffrey A, Suh, Edward M, Domanico, Paul L, Rose, Dudley

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Dual Inhibition of Human Type 4 Phosphodiesterase Isostates by (R,R)-(±)-Methyl 3-Acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate von Tian, Gaochao, Rocque, Warren J, Wiseman, Jeffrey S, Thompson, Irene Z, Holmes, William D, Domanico, Paul L, Stafford, Jeffrey A, Feldman, Paul L, Luther, Michael A

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Introduction of a conformational switching element on a pyrrolidine ring. Synthesis and evaluation of methyl (R,R)-(.+-.)-3-acetyl-4-[3- (cyclopentyloxy)-4-methoxyphenyl]-3- methyl... von Stafford, Jeffrey A, Veal, James M, Feldman, Paul L, Valvano, Nicole L, Baer, Philip G, Brackeen, Marcus F, Brawley, E. Sloan, Connolly, Kevin M, Domanico, Paul L

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Phenylalanine hydroxylase: absolute configuration and source of oxygen of the 4a-hydroxytetrahydropterin species von Dix, Thomas A, Bollag, Gideon E, Domanico, Paul, Benkovic, Stephen J

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Phosphodiesterase type IV (PDE IV) inhibition. Synthesis and evaluation of a series of 1,3,4-trisubstituted pyrrolidines von Stafford, Jeffrey A, Valvano, Nicole L, Feldman, Paul L, Sloan Brawley, E, Cowan, David J, Domanico, Paul L, Leesnitzer, Michael A, Rose, Dudley A, Stimpson, Stephen A, Strickland, Alan B, Unwalla, Rayomand J, Verghese, Margrith W

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Cleavage of dT8 and dT8 phosphorothioyl analogues by Escherichia coli DNA topoisomerase I: product and rate analysis von Domanico, Paul L, Tse-Dinh, Yuk Ching

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Adenosine 5'-O-(3-thiotriphosphate) hydrolysis by dynein von Shimizu, Takashi, Katsura, Tatsuo, Domanico, Paul L, Marchese-Ragona, Silvio P, Johnson, Kenneth A

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17.beta.-(N-tert-Butylcarbamoyl)-4-aza-5.alpha.-androstan-1-en-3-one Is an Active Site-Directed Slow Time-Dependent Inhibitor of Human Steroid 5.alpha.-Reductase 1 von Tian, Gaochao, Stuart, J. Darren, Moss, Marcia L, Domanico, Paul L, Bramson, H. Neal, Patel, Indravadan R, Kadwell, Sue H, Overton, Laurie K, Kost, Thomas A

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Unambiguous stereochemical course of rabbit liver fructose bisphosphatase hydrolysis von Domanico, Paul L, Rahil, Jubrail F, Benkovic, Stephen J

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The 384-Well Plate: Pros and Cons von Janzen, Bill, Domanico, Paul

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Experimental design for high-throughput screening von Lutz, Michael W., Menius, J. Alan, Choi, Tony D., Gooding Laskody, Rebecca, Domanico, Paul L., Goetz, Aaron S., Saussy, David L.

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