Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease von Jiang, Yutong, Andrews, Steven W., Condroski, Kevin R., Buckman, Brad, Serebryany, Vlad, Wenglowsky, Steve, Kennedy, April L., Madduru, Machender R., Wang, Bin, Lyon, Michael, Doherty, George A., Woodard, Benjamin T., Lemieux, Christine, Do, Mary Geck, Zhang, Hailong, Ballard, Joshua, Vigers, Guy, Brandhuber, Barbra J., Stengel, Peter, Josey, John A., Beigelman, Leonid, Blatt, Lawrence, Seiwert, Scott D.

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An Asymmetric Synthesis of the Tricyclic Core and a Formal Total Synthesis of Roseophilin via an Enyne Metathesis von Trost, Barry M, Doherty, George A

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SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT) von Curtin, Michael L., Heyman, H. Robin, Clark, Richard F., Sorensen, Bryan K., Doherty, George A., Hansen, T. Matthew, Frey, Robin R., Sarris, Kathy A., Aguirre, Ana L., Shrestha, Anurupa, Tu, Noah, Woller, Kevin, Pliushchev, Marina A., Sweis, Ramzi F., Cheng, Min, Wilsbacher, Julie L., Kovar, Peter J., Guo, Jun, Cheng, Dong, Longenecker, Kenton L., Raich, Diana, Korepanova, Alla V., Soni, Nirupama B., Algire, Mikkel A., Richardson, Paul L., Marin, Violeta L., Badagnani, Ilaria, Vasudevan, Anil, Buchanan, F. Greg, Maag, David, Chiang, Gary G., Tse, Chris, Michaelides, Michael R.

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The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma von Rynne, Jennifer, Ortiz-Zapater, Elena, Bagley, Dustin C, Zanin, Onofrio, Doherty, George, Kanabar, Varsha, Ward, Jon, Jackson, David J, Parsons, Maddy, Rosenblatt, Jody, Adcock, Ian M, Martinez-Nunez, Rocio T

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Discovery of A‑1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL‑XL Inhibitor von Wang, Le, Doherty, George A, Judd, Andrew S, Tao, Zhi-Fu, Hansen, T. Matthew, Frey, Robin R, Song, Xiaohong, Bruncko, Milan, Kunzer, Aaron R, Wang, Xilu, Wendt, Michael D, Flygare, John A, Catron, Nathaniel D, Judge, Russell A, Park, Chang H, Shekhar, Shashank, Phillips, Darren C, Nimmer, Paul, Smith, Morey L, Tahir, Stephen K, Xiao, Yu, Xue, John, Zhang, Haichao, Le, Phuong N, Mitten, Michael J, Boghaert, Erwin R, Gao, Wenqing, Kovar, Peter, Choo, Edna F, Diaz, Dolores, Fairbrother, Wayne J, Elmore, Steven W, Sampath, Deepak, Leverson, Joel D, Souers, Andrew James

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Social Entrepreneurship: A Look at Social Change von Doherty, George W.

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Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines von Wei, Jia, Pouwels, Koen B., Stoesser, Nicole, Matthews, Philippa C., Diamond, Ian, Studley, Ruth, Rourke, Emma, Cook, Duncan, Bell, John I., Newton, John N., Farrar, Jeremy, Howarth, Alison, Marsden, Brian D., Hoosdally, Sarah, Jones, E. Yvonne, Stuart, David I., Crook, Derrick W., Peto, Tim E. A., Walker, A. Sarah, Eyre, David W.

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Discovery of diphenyl lactam derivatives as N-type calcium channel blockers von Doherty, George A., Bhatia, Pramila, Vortherms, Timothy A., Marsh, Kennan C., Wetter, Jill M., Mack, Helmut, Scott, Victoria E., Jarvis, Michael F., Stewart, Andrew O.

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Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison von Ainsworth, Mark, Andersson, Monique, Auckland, Kathryn, Baillie, J Kenneth, Barnes, Eleanor, Beer, Sally, Blackwell, Luke, Borak, Martyna, Bown, Abbie, Brooks, Tim, Burgess-Brown, Nicola A, Camara, Susana, Catton, Matthew, Chau, Kevin K., Clutterbuck, Elizabeth, Coker, Jesse, Crawford-Jones, David, Crook, Derrick W, D'Arcangelo, Silvia, Dequaire, Julie M M, Dimitriadis, Stavros, Dingle, Kate E, Doherty, George, Dong, Tao, Dunachie, Susanna J, Ebner, Daniel, Emmenegger, Marc, Espinosa, Alexis, Eyre, David W, Fassih, Shayan, Felle, Sally, Fernandez-Cid, Alejandra, Fernandez Mendoza, Maria, Fordwoh, Thomas, Fox McKee, Deborah, Frater, John, Gallardo Sanchez, Veronica, Gent, Nick, Georgiou, Dominique, Groves, Christopher J, Hammond, Peter M, Hatch, Stephanie B., Hill, Jennifer, Howarth, Alison, Jones, Elizabeth, Kavanagh, James, Kirton, Richard, Klenerman, Paul, Knight, Julian C, Koukouflis, Leonidas, Kwok, Andrew, Leuschner, Ullrich, Levin, Robert, Linder, Aline, Lockett, Teresa, Marinou, Spyridoula, Martinez, Jose, Martins Ferreira, Lucas, Mason, Lara, Matthews, Philippa C, Mentzer, Alexander J, Mobbs, Alexander, Mongkolsapaya, Juthathip, Mukhopadhyay, Shubhashish M M, Neville, Matthew J, Oakley, Sarah, Oliveira, Marta, Otter, Ashley, Pascoe, Jordan, Perez, Elena, Perumal, Prem K, Peto, Timothy E A, Pickford, Hayleah, Ploeg, Rutger J, Richardson, Anastasia, Ritter, Thomas G, Roberts, David J, Rodger, Gillian, Rollier, Christine S, Rowe, Cathy, Rudkin, Justine K, Screaton, Gavin, Semple, Malcolm G, Sienkiewicz, Alex, Silva-Reyes, Laura, Skelly, Donal T, Sobrino Diaz, Alberto, Stafford, Lizzie, Stockdale, Lisa, Stoesser, Nicole, Stuart, David I, Thraves, Hannah, Vipond, Richard, Walker, Timothy M, Wareing, Susan, Warren, Yolanda, Wells, Charlie, Wilson, Clare, Withycombe, Kate, Young, Rebecca K

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Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom von Wei, Jia, Stoesser, Nicole, Matthews, Philippa C., Ayoubkhani, Daniel, Studley, Ruth, Bell, Iain, Bell, John I., Newton, John N., Farrar, Jeremy, Diamond, Ian, Rourke, Emma, Howarth, Alison, Marsden, Brian D., Hoosdally, Sarah, Jones, E. Yvonne, Stuart, David I., Crook, Derrick W., Peto, Tim E. A., Pouwels, Koen B., Eyre, David W., Walker, A. Sarah

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Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study von Eyre, David W., Lumley, Sheila F., O'Donnell, Denise, Campbell, Mark, Sims, Elizabeth, Lawson, Elaine, Warren, Fiona, James, Tim, Cox, Stuart, Howarth, Alison, Doherty, George, Hatch, Stephanie B., Kavanagh, James, Chau, Kevin K., Fowler, Philip W., Swann, Jeremy, Volk, Denis, Yang-Turner, Fan, Stoesser, Nicole, Matthews, Philippa C., Dudareva, Maria, Davies, Timothy, Shaw, Robert H., Peto, Leon, Downs, Louise O., Vogt, Alexander, Amini, Ali, Young, Bernadette C., Drennan, Philip George, Mentzer, Alexander J., Skelly, Donal T., Karpe, Fredrik, Neville, Matt J., Andersson, Monique, Brent, Andrew J., Jones, Nicola, Ferreira, Lucas Martins, Christott, Thomas, Marsden, Brian D., Hoosdally, Sarah, Cornall, Richard, Crook, Derrick W., Stuart, David, Screaton, Gavin, Peto, Timothy E. A., Holthof, Bruno, O'Donnell, Anne-Marie, Ebner, Daniel, Conlon, Christopher P., Jeffery, Katie, Walker, Timothy M.

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Anti-spike antibody response to natural SARS-CoV-2 infection in the general population von Wei, Jia, Matthews, Philippa C., Stoesser, Nicole, Maddox, Thomas, Lorenzi, Luke, Studley, Ruth, Bell, John I., Newton, John N., Farrar, Jeremy, Diamond, Ian, Rourke, Emma, Howarth, Alison, Marsden, Brian D., Hoosdally, Sarah, Jones, E. Yvonne, Stuart, David I., Crook, Derrick W., Peto, Tim E. A., Pouwels, Koen B., Walker, A. Sarah, Eyre, David W.

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Tracking the Emergence of SARS-CoV-2 Alpha Variant in the United Kingdom von Walker, A. Sarah, Vihta, Karina-Doris, Gethings, Owen, Pritchard, Emma, Jones, Joel, House, Thomas, Bell, Iain, Bell, John I, Newton, John N, Farrar, Jeremy, Diamond, Ian, Studley, Ruth, Rourke, Emma, Hay, Jodie, Hopkins, Susan, Crook, Derrick, Peto, Tim, Matthews, Philippa C, Eyre, David W, Stoesser, Nicole, Pouwels, Koen B

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An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Anti... von Lumley, Sheila F, Rodger, Gillian, Constantinides, Bede, Sanderson, Nicholas, Chau, Kevin K, Street, Teresa L, O’Donnell, Denise, Howarth, Alison, Hatch, Stephanie B, Marsden, Brian D, Cox, Stuart, James, Tim, Warren, Fiona, Peck, Liam J, Ritter, Thomas G, de Toledo, Zoe, Warren, Laura, Axten, David, Cornall, Richard J, Jones, E Yvonne, Stuart, David I, Screaton, Gavin, Ebner, Daniel, Hoosdally, Sarah, Chand, Meera, Crook, Derrick W, O’Donnell, Anne-Marie, Conlon, Christopher P, Pouwels, Koen B, Walker, A Sarah, Peto, Tim E A, Hopkins, Susan, Walker, Timothy M, Stoesser, Nicole E, Matthews, Philippa C, Jeffery, Katie, Eyre, David W

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Symptoms and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Positivity in the General Population in the United Kingdom von Vihta, Karina Doris, Pouwels, Koen B, Peto, Tim E A, Pritchard, Emma, Eyre, David W, House, Thomas, Gethings, Owen, Studley, Ruth, Rourke, Emma, Cook, Duncan, Diamond, Ian, Crook, Derrick, Matthews, Philippa C, Stoesser, Nicole, Walker, Ann Sarah

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N-Aryl 2,6-Dimethoxybiphenylalanine Analogues as VLA-4 Antagonists von Doherty, George A, Kamenecka, Theodore, McCauley, Ermenegilda, Van Riper, Gail, Mumford, Richard A, Tong, Sharon, Hagmann, William K

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Genocide: A Human Condition? von Doherty, George W.

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Protection against SARS-CoV-2 Omicron BA.4/5 variant following booster vaccination or breakthrough infection in the UK von Wei, Jia, Matthews, Philippa C., Stoesser, Nicole, Newton, John N., Diamond, Ian, Studley, Ruth, Taylor, Nick, Bell, John I., Farrar, Jeremy, Kolenchery, Jaison, Marsden, Brian D., Hoosdally, Sarah, Jones, E. Yvonne, Stuart, David I., Crook, Derrick W., Peto, Tim E. A., Walker, A. Sarah, Pouwels, Koen B., Eyre, David W.

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Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-X-L Inhibitor von Wang, Le, Doherty, George A., Judd, Andrew S., Tao, Zhi-Fu, Hansen, T. Matthew, Frey, Robin R., Song, Xiaohong, Bruncko, Milan, Kunzer, Aaron R., Wang, Xilu, Wendt, Michael D., Flygare, John A., Catron, Nathaniel D., Judge, Russell A., Park, Chang H., Shekhar, Shashank, Phillips, Darren C., Nimmer, Paul, Smith, Morey L., Tahir, Stephen K., Xiao, Yu, Xue, John, Zhang, Haichao, Le, Phuong N., Mitten, Michael J., Boghaert, Erwin R., Gao, Wenqing, Kovar, Peter, Choo, Edna F., Diaz, Dolores, Fairbrother, Wayne J., Elmore, Steven W., Sampath, Deepak, Leverson, Joel D., Souers, Andrew James

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Community prevalence of SARS-CoV-2 in England from April to November, 2020: results from the ONS Coronavirus Infection Survey von Pouwels, Koen B, House, Thomas, Pritchard, Emma, Robotham, Julie V, Birrell, Paul J, Gelman, Andrew, Vihta, Karina-Doris, Bowers, Nikola, Boreham, Ian, Thomas, Heledd, Bell, Iain, Bell, John I, Newton, John N, Farrar, Jeremy, Benton, Pete, Walker, Ann Sarah, Pouwels, Koen B., Crook, Derrick, Matthews, Philippa C., Peto, Tim, Pritchard, Emma, Stoesser, Nicole, Vihta, Karina-Doris, Howarth, Alison, Doherty, George, Kavanagh, James, Chau, Kevin K., Martins Ferreira, Lucas, Marsden, Brian D., Mongkolsapaya, Juthathip, Cornall, Richard, Stuart, David I., Screaton, Gavin, Bell, John, Cox, Stuart, Paddon, Kevin, James, Tim, House, Thomas, Newton, John N., Birrell, Paul, Sheppard, Tim, Athey, Graham, Moody, Dan, Curry, Leigh, Brereton, Pamela, Hay, Jodie, Vansteenhouse, Harper, Benton, Pete, Rourke, Emma, Henry, Sarah, Scruton, James, Stokes, Peter, Thomas, Tina, Allen, John, Black, Russell, Bovill, Heather, Braunholtz, David, Brown, Dominic, Collyer, Sarah, Crees, Megan, Daglish, Colin, Davies, Byron, Donnarumma, Hannah, Douglas-Mann, Julia, Felton, Antonio, Finselbach, Hannah, Fordham, Eleanor, Ipser, Alberta, Jenkins, Joe, Kent, Katherine, Kerai, Geeta, Lloyd, Lina, Masding, Victoria, Osborn, Ellie, Patel, Alpi, Pereira, Elizabeth, Pett, Tristan, Reeve, Donna, Shah, Palvi, Snook, Ruth, Studley, Ruth, Sutherland, Esther, Swinn, Eliza, Thomas, Heledd, Tudor, Anna, Weston, Joshua, Leib, Shayla, Tierney, James, Farkas, Gabor, Cobb, Raf, Compton, Lewis, Irving, James, Clarke, John, Mullis, Rachel, Ireland, Lorraine, Airimitoaie, Diana, Fisher, Sarah, Moore, Zoe, McLean, James, Kerby, Matt

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