Simufilam suppresses overactive mTOR and restores its sensitivity to insulin in Alzheimer's disease patient lymphocytes von Wang, Hoau-Yan, Pei, Zhe, Lee, Kuo-Chieh, Nikolov, Boris, Doehner, Tamara, Puente, John, Friedmann, Nadav, Burns, Lindsay H

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Encouraging interim results at 9 months from an open‐label study of simufilam in patients with Alzheimer’s disease von Burns, Lindsay H, Doehner, Tamara, Puente, John, Beck, Brian, Gonzalez‐Rojas, Yaneicy, Lopez‐Brignoni, Evelyn, Nikolov, Boris, Wang, Hoau‐Yan, Pei, Zhe, Hernandez, Antonio, Crowley, Carrie A, Friedmann, Nadav

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Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin von Schmalbrock, Laura K., Dolnik, Anna, Cocciardi, Sibylle, Sträng, Eric, Theis, Frauke, Jahn, Nikolaus, Panina, Ekaterina, Blätte, Tamara J., Herzig, Julia, Skambraks, Sabrina, Rücker, Frank G., Gaidzik, Verena I., Paschka, Peter, Fiedler, Walter, Salih, Helmut R., Wulf, Gerald, Schroeder, Thomas, Lübbert, Michael, Schlenk, Richard F., Thol, Felicitas, Heuser, Michael, Larson, Richard A., Ganser, Arnold, Stunnenberg, Hendrik G., Minucci, Saverio, Stone, Richard M., Bloomfield, Clara D., Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars

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getITD for FLT3-ITD-based MRD monitoring in AML von Blätte, Tamara J., Schmalbrock, Laura K., Skambraks, Sabrina, Lux, Susanne, Cocciardi, Sibylle, Dolnik, Anna, Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars

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Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation von Cocciardi, Sibylle, Dolnik, Anna, Kapp-Schwoerer, Silke, Rücker, Frank G., Lux, Susanne, Blätte, Tamara J., Skambraks, Sabrina, Krönke, Jan, Heidel, Florian H., Schnöder, Tina M., Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Teleanu, Veronica, Göhring, Gudrun, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Weber, Daniela, Sträng, Eric, Kestler, Hans A., Döhner, Hartmut, Bullinger, Lars, Döhner, Konstanze

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Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype von Rücker, Frank G, Dolnik, Anna, Blätte, Tamara J, Teleanu, Veronica, Ernst, Aurélie, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars

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Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia von Hirsch, Susanne, Blätte, Tamara J, Grasedieck, Sarah, Cocciardi, Sibylle, Rouhi, Arefeh, Jongen-Lavrencic, Mojca, Paschka, Peter, Krönke, Jan, Gaidzik, Verena I, Döhner, Hartmut, Schlenk, Richard F, Kuchenbauer, Florian, Döhner, Konstanze, Dolnik, Anna, Bullinger, Lars

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Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results von Rücker, Frank G., Du, Ling, Luck, Tamara J., Benner, Axel, Krzykalla, Julia, Gathmann, Insa, Voso, Maria Teresa, Amadori, Sergio, Prior, Thomas W., Brandwein, Joseph M., Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Savoie, Lynn, Sierra, Jorge, Pallaud, Celine, Sanz, Miguel A., Jansen, Joop H., Niederwieser, Dietger, Fischer, Thomas, Ehninger, Gerhard, Heuser, Michael, Ganser, Arnold, Bullinger, Lars, Larson, Richard A., Bloomfield, Clara D., Stone, Richard M., Döhner, Hartmut, Thiede, Christian, Döhner, Konstanze

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Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing von Dolnik, Anna, Engelmann, Julia C., Scharfenberger-Schmeer, Maren, Mauch, Julian, Kelkenberg-Schade, Sabine, Haldemann, Berit, Fries, Tamara, Krönke, Jan, Kühn, Michael W.M., Paschka, Peter, Kayser, Sabine, Wolf, Stephan, Gaidzik, Verena I., Schlenk, Richard F., Rücker, Frank G., Döhner, Hartmut, Lottaz, Claudio, Döhner, Konstanze, Bullinger, Lars

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Deregulated expression of circular RNAs in acute myeloid leukemia von Lux, Susanne, Blätte, Tamara J., Gillissen, Bernhard, Richter, Antje, Cocciardi, Sibylle, Skambraks, Sabrina, Schwarz, Klaus, Schrezenmeier, Hubert, Döhner, Hartmut, Döhner, Konstanze, Dolnik, Anna, Bullinger, Lars

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Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription von Edelmann, Jennifer, Holzmann, Karlheinz, Tausch, Eugen, Saunderson, Emily A, Jebaraj, Billy M C, Steinbrecher, Daniela, Dolnik, Anna, Blätte, Tamara J, Landau, Dan A, Saub, Jenny, Estenfelder, Sven, Ibach, Stefan, Cymbalista, Florence, Leblond, Veronique, Delmer, Alain, Bahlo, Jasmin, Robrecht, Sandra, Fischer, Kirsten, Goede, Valentin, Bullinger, Lars, Wu, Catherine J, Mertens, Daniel, Ficz, Gabriella, Gribben, John G, Hallek, Michael, Döhner, Hartmut, Stilgenbauer, Stephan

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Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma von Bohl, Stephan R., Schmalbrock, Laura K., Bauhuf, Imke, Meyer, Tatjana, Dolnik, Anna, Szyska, Martin, Blätte, Tamara J., Knödler, Sarah, Röhner, Linda, Miller, Denise, Kull, Miriam, Langer, Christian, Döhner, Hartmut, Letai, Anthony, Damm, Frederik, Heckl, Dirk, Bullinger, Lars, Krönke, Jan

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The relationship between cholesterol and survival in patients with chronic heart failure. Commentary von RAUCHHAUS, Mathias, CLARK, Andrew L, DOEHNER, Wolfram, DAVOS, Constantinos, BOLGER, Aidan, SHARMA, Rakesh, COATS, Andrew J. S, ANKER, Stefan D, FONAROW, Gregg C, HORWICH, Tamara B

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