Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling von Zhang, Zhong-Yin, Dodd, Garron T, Tiganis, Tony

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Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat von Dodd, Garron T., Decherf, Stephanie, Loh, Kim, Simonds, Stephanie E., Wiede, Florian, Balland, Eglantine, Merry, Troy L., Münzberg, Heike, Zhang, Zhong-Yin, Kahn, Barbara B., Neel, Benjamin G., Bence, Kendra K., Andrews, Zane B., Cowley, Michael A., Tiganis, Tony

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The Thermogenic Effect of Leptin Is Dependent on a Distinct Population of Prolactin-Releasing Peptide Neurons in the Dorsomedial Hypothalamus von Dodd, Garron T., Worth, Amy A., Nunn, Nicolas, Korpal, Aaron K., Bechtold, David A., Allison, Margaret B., Myers, Martin G., Statnick, Michael A., Luckman, Simon M.

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Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity von Dodd, Garron T., Xirouchaki, Chrysovalantou E., Eramo, Matthew, Mitchell, Christina A., Andrews, Zane B., Henry, Belinda A., Cowley, Michael A., Tiganis, Tony

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Insulin on the brain: The role of central insulin signalling in energy and glucose homeostasis von Beddows, Cait A., Dodd, Garron T.

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PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours von Wiede, Florian, Lu, Kun‐Hui, Du, Xin, Liang, Shuwei, Hochheiser, Katharina, Dodd, Garron T, Goh, Pei K, Kearney, Conor, Meyran, Deborah, Beavis, Paul A, Henderson, Melissa A, Park, Simone L, Waithman, Jason, Zhang, Sheng, Zhang, Zhong‐Yin, Oliaro, Jane, Gebhardt, Thomas, Darcy, Phillip K, Tiganis, Tony

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Insulin regulates POMC neuronal plasticity to control glucose metabolism von Dodd, Garron T, Michael, Natalie J, Lee-Young, Robert S, Mangiafico, Salvatore P, Pryor, Jack T, Munder, Astrid C, Simonds, Stephanie E, Brüning, Jens Claus, Zhang, Zhong-Yin, Cowley, Michael A, Andrikopoulos, Sofianos, Horvath, Tamas L, Spanswick, David, Tiganis, Tony

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Leptin Signaling in the Arcuate Nucleus Reduces Insulin’s Capacity to Suppress Hepatic Glucose Production in Obese Mice von Balland, Eglantine, Chen, Weiyi, Dodd, Garron T., Conductier, Gregory, Coppari, Roberto, Tiganis, Tony, Cowley, Michael A.

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The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling von Worth, Amy A, Shoop, Rosemary, Tye, Katie, Feetham, Claire H, D'Agostino, Giuseppe, Dodd, Garron T, Reimann, Frank, Gribble, Fiona M, Beebe, Emily C, Dunbar, James D, Alexander-Chacko, Jesline T, Sindelar, Dana K, Coskun, Tamer, Emmerson, Paul J, Luckman, Simon M

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TCPTP Regulates Insulin Signalling in AgRP Neurons to Coordinate Glucose Metabolism with Feeding von Dodd, Garron T, Lee-Young, Robert S, Brüning, Jens C, Tiganis, Tony

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Pathogenic hypothalamic extracellular matrix promotes metabolic disease von Beddows, Cait A., Shi, Feiyue, Horton, Anna L., Dalal, Sagar, Zhang, Ping, Ling, Chang-Chun, Yong, V. Wee, Loh, Kim, Cho, Ellie, Karagiannis, Chris, Rose, Adam J., Montgomery, Magdalene K., Gregorevic, Paul, Watt, Matthew J., Packer, Nicolle H., Parker, Benjamin L., Brown, Robyn M., Moh, Edward S. X., Dodd, Garron T.

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The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice von Dodd, Garron T, Mancini, Giacomo, Lutz, Beat, Luckman, Simon M

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Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice von Merry, Troy L., Tran, Melanie, Dodd, Garron T., Mangiafico, Salvatore P., Wiede, Florian, Kaur, Supreet, McLean, Catriona L., Andrikopoulos, Sofianos, Tiganis, Tony

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Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus von Kyriakou, Eleni, Schmidt, Stefanie, Dodd, Garron T, Pfuhlmann, Katrin, Simonds, Stephanie E, Lenhart, Dominik, Geerlof, Arie, Schriever, Sonja C, De Angelis, Meri, Schramm, Karl-Werner, Plettenburg, Oliver, Cowley, Michael A, Tiganis, Tony, Tschöp, Matthias H, Pfluger, Paul T, Sattler, Michael, Messias, Ana C

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Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide‑1 Analogue von Chandrashekar, Chaitra, Lin, Feng, Nishiuchi, Yuji, Mohammed, Sam F., White, Barbara F., Arsenakis, Yanni, Yuliantie, Elita, Zhao, Peishen, van Dun, Sam, Koijen, Anna, Kajihara, Yasuhiro, Wootten, Denise, Dodd, Garron T., van den Bos, Leendert J., Wade, John D., Hossain, Mohammed Akhter

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High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage von Merry, Troy L, Tran, Melanie, Stathopoulos, Maria, Wiede, Florian, Fam, Barbara Christianne, Dodd, Garron T, Clarke, Iain, Watt, Matthew J, Andrikopoulos, Sofianos, Tiganis, Tony

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TET2: the fat controller of leptin von Goldsmith, Callen C, Dodd, Garron T

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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function von Blazev, Ronnie, Carl, Christian S, Ng, Yaan-Kit, Molendijk, Jeffrey, Voldstedlund, Christian T, Zhao, Yuanyuan, Xiao, Di, Kueh, Andrew J, Miotto, Paula M, Haynes, Vanessa R, Hardee, Justin P, Chung, Jin D, McNamara, James W, Qian, Hongwei, Gregorevic, Paul, Oakhill, Jonathan S, Herold, Marco J, Jensen, Thomas E, Lisowski, Leszek, Lynch, Gordon S, Dodd, Garron T, Watt, Matthew J, Yang, Pengyi, Kiens, Bente, Richter, Erik A, Parker, Benjamin L

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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding von Dodd, Garron T., Andrews, Zane B., Simonds, Stephanie E., Michael, Natalie J., DeVeer, Michael, Brüning, Jens C., Spanswick, David, Cowley, Michael A., Tiganis, Tony

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PTPN2 regulates T cell lineage commitment and αβ versus γδ specification von Wiede, Florian, Dudakov, Jarrod A, Lu, Kun-Hui, Dodd, Garron T, Butt, Tariq, Godfrey, Dale I, Strasser, Andreas, Boyd, Richard L, Tiganis, Tony

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