Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles von Hatit, Marine Z. C., Lokugamage, Melissa P., Dobrowolski, Curtis N., Paunovska, Kalina, Ni, Huanzhen, Zhao, Kun, Vanover, Daryll, Beyersdorf, Jared, Peck, Hannah E., Loughrey, David, Sato, Manaka, Cristian, Ana, Santangelo, Philip J., Dahlman, James E.

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Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles von Hatit, Marine Z. C., Lokugamage, Melissa P., Dobrowolski, Curtis N., Paunovska, Kalina, Ni, Huanzhen, Zhao, Kun, Vanover, Daryll, Beyersdorf, Jared, Peck, Hannah E., Loughrey, David, Sato, Manaka, Cristian, Ana, Santangelo, Philip J., Dahlman, James E.

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Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery von Hatit, Marine Z. C., Dobrowolski, Curtis N., Lokugamage, Melissa P., Loughrey, David, Ni, Huanzhen, Zurla, Chiara, Da Silva Sanchez, Alejandro J., Radmand, Afsane, Huayamares, Sebastian G., Zenhausern, Ryan, Paunovska, Kalina, Peck, Hannah E., Kim, Jinwhan, Sato, Manaka, Feldman, Jacob I., Rivera, Michael-Alexander, Cristian, Ana, Kim, YongTae, Santangelo, Philip J., Dahlman, James E.

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Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart von Radmand, Afsane, Kim, Hyejin, Beyersdorf, Jared, Dobrowolski, Curtis N, Zenhausern, Ryan, Paunovska, Kalina, Huayamares, Sebastian G, Hua, Xuanwen, Han, Keyi, Loughrey, David, Hatit, Marine Z C, Del Cid, Ada, Ni, Huanzhen, Shajii, Aram, Li, Andrea, Muralidharan, Abinaya, Peck, Hannah E, Tiegreen, Karen E, Jia, Shu, Santangelo, Philip J, Dahlman, James E

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Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency von Nguyen, Kien, Das, Biswajit, Dobrowolski, Curtis, Karn, Jonathan

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Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation von Kien Nguyen, Dobrowolski, Curtis, Shukla, Meenakshi, Cho, Won-Kyung, Luttge, Benjamin, Karn, Jonathan

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Entry of Polarized Effector Cells into Quiescence Forces HIV Latency von Dobrowolski, Curtis, Valadkhan, Saba, Graham, Amy C, Shukla, Meenakshi, Ciuffi, Angela, Telenti, Amalio, Karn, Jonathan

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Therapeutic RNA Delivery for COVID and Other Diseases von Dobrowolski, Curtis, Paunovska, Kalina, Hatit, Marine Z. C., Lokugamage, Melissa P., Dahlman, James E.

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Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells von Alvarez-Carbonell, David, Garcia-Mesa, Yoelvis, Milne, Stephanie, Das, Biswajit, Dobrowolski, Curtis, Rojas, Roxana, Karn, Jonathan

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Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda von Joussef-Piña, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M, Boom, W Henry, Karn, Jonathan, Quiñones-Mateu, Miguel E

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Negative Elongation Factor Is Required for the Maintenance of Proviral Latency but Does Not Induce Promoter-Proximal Pausing of RNA Polymerase II on the HIV Long Terminal Repeat von Jadlowsky, Julie K., Wong, Julian Y., Graham, Amy C., Dobrowolski, Curtis, Devor, Renee L., Adams, Mark D., Fujinaga, Koh, Karn, Jonathan

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Sex Differences in Human Immunodeficiency Virus Persistence and Reservoir Size During Aging von Gianella, Sara, Rawlings, Stephen A, Dobrowolski, Curtis, Nakazawa, Masato, Chaillon, Antoine, Strain, Matthew, Layman, Laura, Caballero, Gemma, Scully, Eileen, Scott, Brianna, Pacis, Caitleen, Weber, Kathleen M, Landay, Alan, Anderson, Christy, Karn, Jonathan

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Detecting Sources of Immune Activation and Viral Rebound in HIV Infection von Wietgrefe, Stephen W, Duan, Lijie, Anderson, Jodi, Marqués, Guillermo, Sanders, Mark, Cummins, Nathan W, Badley, Andrew D, Dobrowolski, Curtis, Karn, Jonathan, Pagliuzza, Amélie, Chomont, Nicolas, Sannier, Gérémy, Dubé, Mathieu, Kaufmann, Daniel E, Zuck, Paul, Wu, Guoxin, Howell, Bonnie J, Reilly, Cavan, Herschhorn, Alon, Schacker, Timothy W, Haase, Ashley T

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The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral even... von Lucera, Mark B, Tilton, Carisa A, Mao, Hongxia, Dobrowolski, Curtis, Tabler, Caroline O, Haqqani, Aiman A, Karn, Jonathan, Tilton, John C

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Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes von Mbonye, Uri R, Gokulrangan, Giridharan, Datt, Manish, Dobrowolski, Curtis, Cooper, Maxwell, Chance, Mark R, Karn, Jonathan

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Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system von Garcia-Mesa, Yoelvis, Jay, Taylor R., Checkley, Mary Ann, Luttge, Benjamin, Dobrowolski, Curtis, Valadkhan, Saba, Landreth, Gary E., Karn, Jonathan, Alvarez-Carbonell, David

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Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery von Dobrowolski, Curtis, Paunovska, Kalina, Schrader Echeverri, Elisa, Loughrey, David, Da Silva Sanchez, Alejandro J., Ni, Huanzhen, Hatit, Marine Z. C., Lokugamage, Melissa P., Kuzminich, Yanina, Peck, Hannah E., Santangelo, Philip J., Dahlman, James E.

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A Reliable Primary Cell Model for HIV Latency: The QUECEL (Quiescent Effector Cell Latency) Method von Shukla, Meenakshi, Kizito, Fredrick, Mbonye, Uri, Nguyen, Kien, Dobrowolski, Curtis, Karn, Jonathan

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Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial von Miller, Jeffrey S., Davis, Zachary B., Helgeson, Erika, Reilly, Cavan, Thorkelson, Ann, Anderson, Jodi, Lima, Noemia S., Jorstad, Siri, Hart, Geoffrey T., Lee, John H., Safrit, Jeffrey T., Wong, Hing, Cooley, Sarah, Gharu, Lavina, Chung, Hyunsoo, Soon-Shiong, Patrick, Dobrowolski, Curtis, Fletcher, Courtney V., Karn, Jonathan, Douek, Daniel C., Schacker, Timothy W.

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Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery von Da Silva Sanchez, Alejandro J., Zhao, Kun, Huayamares, Sebastian G., Hatit, Marine Z.C., Lokugamage, Melissa P., Loughrey, David, Dobrowolski, Curtis, Wang, Shuaishuai, Kim, Hyejin, Paunovska, Kalina, Kuzminich, Yanina, Dahlman, James E.

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