293 Inhibition of the cell cycle regulated Cdc7 kinase pathway is an efficacious therapeutic approach for hematologic malignancies and solid tumors von Santos, R, Shum, D, Carrillo, D, Zhang, R, Churchill, M, Mukherjee, S, Brentjens, R, Radu, C, Kelly, T.J, Djaballah, H, Frattini, M.G

Volltext

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors von Shukla, Neerav, Somwar, Romel, Smith, Roger S, Ambati, Sri, Munoz, Stanley, Merchant, Melinda, D'Arcy, Padraig, Wang, Xin, Kobos, Rachel, Antczak, Christophe, Bhinder, Bhavneet, Shum, David, Radu, Constantin, Yang, Guangbin, Taylor, Barry S, Ng, Charlotte K Y, Weigelt, Britta, Khodos, Inna, de Stanchina, Elisa, Reis-Filho, Jorge S, Ouerfelli, Ouathek, Linder, Stig, Djaballah, Hakim, Ladanyi, Marc

Volltext

A Class of Allosteric Caspase Inhibitors Identified by High-Throughput Screening von Feldman, Taya, Kabaleeswaran, Venkataraman, Jang, Se Bok, Antczak, Christophe, Djaballah, Hakim, Wu, Hao, Jiang, Xuejun

Volltext

EP08.02-055 Targeting Lung Adenocarcinoma Cells with a Novel Disulfide Reductase Inhibitor von Johnson, F., Ferrarone, J., Liu, A., Brandstädter, C., Munuganti, R., Farnsworth, D., Lu, D., Luu, J., Sihota, T., Jansen, S., Nagelberg, A., Shi, R., Forcina, G., Zhang, X., Cheng, G., Spencer Miko, S., de Rappard-Yuswack, G., Sorensen, P., Dixon, S., Guha, U., Becker, K., Djaballah, H., Somwar, R., Varmus, H., Morin, G., Lockwood, W.

Volltext

High-content assay to identify inhibitors of dengue virus infection von Shum, David, Smith, Jessica L, Hirsch, Alec J, Bhinder, Bhavneet, Radu, Constantin, Stein, David A, Nelson, Jay A, Früh, Klaus, Djaballah, Hakim

Volltext

Domain-based biosensor assay to screen for epidermal growth factor receptor modulators in live cells von Antczak, Christophe, Bermingham, Alun, Calder, Paul, Malkov, Dmitry, Song, Keming, Fetter, John, Djaballah, Hakim

Volltext

A preliminary study of the activation of endogenous pancreatic exocrine enzymes during automated porcine islet isolation von White, S A, Djaballah, H, Hughes, D P, Roberts, D L, Contractor, H H, Pathak, S, London, N J

Volltext

A viral inhibitor of peptide transporters for antigen presentation von Früh, Klaus, Ahn, Kwangseog, Djaballah, Hakim, Sempé, Pascal, van Endert, Peter M, Tampé, Robert, Peterson, Per A, Yang, Young

Volltext

An arrayed genome-scale lentiviral-enabled short hairpin RNA screen identifies lethal and rescuer gene candidates von Bhinder, Bhavneet, Antczak, Christophe, Ramirez, Christina N, Shum, David, Liu-Sullivan, Nancy, Radu, Constantin, Frattini, Mark G, Djaballah, Hakim

Volltext

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus protein ICP47 von Ahn, K, Meyer, TH, Uebel, S, Sempe, P, Djaballah, H, Yang, Y, Peterson, P A, Frueh, K, Tampe, R

Volltext

Validation of a high-content screening assay using whole-well imaging of transformed phenotypes von Ramirez, Christina N, Ozawa, Tatsuya, Takagi, Toshimitsu, Antczak, Christophe, Shum, David, Graves, Robert, Holland, Eric C, Djaballah, Hakim

Volltext

A high-throughput scintillation proximity-based assay for human DNA ligase IV von Tseng, Hui-Min, Shum, David, Bhinder, Bhavneet, Escobar, Sindy, Veomett, Nicholas J, Tomkinson, Alan E, Gin, David Y, Djaballah, Hakim, Scheinberg, David A

Volltext

The multicatalytic proteinase complex (proteasome) : structure and conformational changes associated with changes in proteolytic activity von HAKIM DJABALLAH, ROWE, A. J, HARDING, S. E, RIVETT, A. J

Volltext

A high-throughput screen for alpha particle radiation protectants von Seideman, Jonathan H, Shum, David, Djaballah, Hakim, Scheinberg, David A

Volltext

An arrayed RNA interference genome-wide screen identifies candidate genes involved in the MicroRNA 21 biogenesis pathway von Shum, David, Bhinder, Bhavneet, Ramirez, Christina N, Radu, Constantin, Calder, Paul A, Beauchamp, Lesslie, Farazi, T, Landthaler, M, Tuschi, T, Magdaleno, Susan, Djaballah, Hakim

Volltext

A Homogenous 384-Well High Throughput Screen for Novel Tumor Necrosis Factor Receptor: Ligand Interactions Using Time Resolved Energy Transfer von Moore, K.J., Turconi, S., Miles-Williams, A., Djaballah, H., Hurskainen, P., Harrop, J., Murray, K.J., Pope, A.J.

Volltext

Identification of selective inhibitors of dedifferentiated liposarcoma cells by high-throughput screening (HTS) von Angeles, C. V., Laxa, B., Shum, D., DeCarolis, P., Gobble, R., Brill, E., Ugras, S., O'Connor, R., Djaballah, H., Singer, S.

Volltext

Reaction of proteasomes with peptidylchloromethanes and peptidyldiazomethanes von SAVORY, P. J, DJABALLAH, H, ANGLIKER, H, SHAW, E, RIVETT, A. J

Volltext

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47 von Ahn, K., Meyer, T. H., Uebel, S., Sempé, P., Djaballah, H., Yang, Y., Peterson, P. A., Früh, K., Tampé, R.

Volltext

Antigen processing by proteasomes: insights into the molecular basis of crypticity von Djaballah, H

Volltext