WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production von Rauner, Martina, Stein, Nicola, Winzer, Maria, Goettsch, Claudia, Zwerina, Jochen, Schett, Georg, Distler, Jörg HW, Albers, Joachim, Schulze, Jochen, Schinke, Thorsten, Bornhäuser, Martin, Platzbecker, Uwe, Hofbauer, Lorenz C

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Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages von Beyer, Christian, Huang, Jingang, Beer, Jürgen, Zhang, Yun, Palumbo-Zerr, Katrin, Zerr, Pawel, Distler, Alfiya, Dees, Clara, Maier, Christiane, Munoz, Louis, Krönke, Gerhard, Uderhardt, Stefan, Distler, Oliver, Jones, Simon, Rose-John, Stefan, Oravecz, Tamas, Schett, Georg, Distler, Jörg HW

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Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss von Lin, Neng-Yu, Chen, Chih-Wei, Kagwiria, Rosebeth, Liang, Ruifang, Beyer, Christian, Distler, Alfiya, Luther, Julia, Engelke, Klaus, Schett, Georg, Distler, Jörg HW

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Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway von López-Isac, Elena, Campillo-Davo, Diana, Bossini-Castillo, Lara, Guerra, Sandra G, Assassi, Shervin, Simeón, Carmen Pilar, Carreira, Patricia, Ortego-Centeno, Norberto, García de la Peña, Paloma, Beretta, Lorenzo, Santaniello, Alessandro, Bellocchi, Chiara, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jörg HW, Voskuyl, Alexandre E, de Vries-Bouwstra, Jeska, Herrick, Ariane, Worthington, Jane, Denton, Christopher P, Fonseca, Carmen, Radstake, Timothy RDJ, Mayes, Maureen D, Martín, Javier

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The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death von Beyer, Christian, Stearns, Nancy A, Giessl, Adreas, Distler, Jörg HW, Schett, Georg, Pisetsky, David S

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Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis von Beyer, Christian, Schett, Georg, Gay, Steffen, Distler, Oliver, Distler, Jörg H W

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Epigenetic factors as drivers of fibrosis in systemic sclerosis von Bergmann, Christina, Distler, Jörg HW

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Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability von Distler, Alfiya, Lang, Veronika, Del Vecchio, Tina, Huang, Jingang, Zhang, Yun, Beyer, Christian, Lin, Neng-Yu, Palumbo-Zerr, Katrin, Distler, Oliver, Schett, Georg, Distler, Jörg HW

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Rationale for the evaluation of nintedanib as a treatment for systemic sclerosis–associated interstitial lung disease von Wollin, Lutz, Distler, Jörg HW, Denton, Christopher P, Gahlemann, Martina

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Targeting TGF-β signaling for the treatment of fibrosis von Györfi, Andrea Hermina, Matei, Alexandru-Emil, Distler, Jörg H.W.

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Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss von Kleyer, Arnd, Scholtysek, Carina, Bottesch, Edith, Hillienhof, Ulrike, Beyer, Christian, Distler, Jörg HW, Tuckermann, Jan P, Schett, Georg, Krönke, Gerhard

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TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis von Dees, Clara, Pötter, Sebastian, Zhang, Yun, Bergmann, Christina, Zhou, Xiang, Luber, Markus, Wohlfahrt, Thomas, Karouzakis, Emmanuel, Ramming, Andreas, Gelse, Kolja, Yoshimura, Akihiko, Jaenisch, Rudolf, Distler, Oliver, Schett, Georg, Distler, Jörg Hw

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Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis von Pachera, Elena, Assassi, Shervin, Salazar, Gloria A, Stellato, Mara, Renoux, Florian, Wunderlin, Adam, Blyszczuk, Przemyslaw, Lafyatis, Robert, Kurreeman, Fina, de Vries-Bouwstra, Jeska, Messemaker, Tobias, Feghali-Bostwick, Carol A, Rogler, Gerhard, van Haaften, Wouter T, Dijkstra, Gerard, Oakley, Fiona, Calcagni, Maurizio, Schniering, Janine, Maurer, Britta, Distler, Jörg Hw, Kania, Gabriela, Frank-Bertoncelj, Mojca, Distler, Oliver

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Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse von Ledein, Laetitia, Léger, Bertrand, Dees, Clara, Beyer, Christian, Distler, Alfiya, Vettori, Serena, Boukaiba, Rachid, Bidouard, Jean Pierre, Schaefer, Matthias, Pernerstorfer, Josef, Ruetten, Hartmut, Jagerschmidt, Alexandre, Janiak, Philip, Distler, Jörg H.W., Distler, Oliver, Illiano, Stéphane

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BCMA-Targeted T-Cell–Engager Therapy for Autoimmune Disease von Hagen, Melanie, Bucci, Laura, Böltz, Sebastian, Nöthling, Danae-Mona, Rothe, Tobias, Anoshkin, Kirill, Raimondo, Maria G., Tur, Carlo, Wirsching, Andreas, Wacker, Jochen, Düsing, Christina, Distler, Jörg H.W., Kuwert, Torsten, Bozec, Aline, Ramming, Andreas, Schett, Georg, Grieshaber-Bouyer, Ricardo

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Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis von Trinh-Minh, Thuong, Chen, Chih-Wei, Tran Manh, Cuong, Li, Yi-Nan, Zhu, Honglin, Zhou, Xiang, Chakraborty, Debomita, Zhang, Yun, Rauber, Simon, Dees, Clara, Lin, Neng-Yu, Kah, Delf, Gerum, Richard, Bergmann, Christina, Kreuter, Alexander, Reuter, Christiane, Groeber-Becker, Florian, Eckes, Beate, Distler, Oliver, Fabry, Ben, Ramming, Andreas, Schambony, Alexandra, Schett, Georg, Distler, Jörg Hw

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A broad look into the future of systemic sclerosis von Riemekasten, Gabriela, Distler, Jörg H.W.

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The role of antifibrotics in the treatment of rheumatoid arthritis–associated interstitial lung disease von Liang, Minrui, Matteson, Eric L., Abril, Andy, Distler, Jörg H.W.

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Nintedanib in patients with systemic sclerosis-associated interstitial lung disease: subgroup analyses by autoantibody status and skin score von Kuwana, Masataka, Allanore, Yannick, Denton, Christopher P, Distler, Jörg Hw, Steen, Virginia, Khanna, Dinesh, Matucci-Cerinic, Marco, Mayes, Maureen D, Volkmann, Elizabeth R, Miede, Corinna, Gahlemann, Martina, Quaresma Lic, Manuel, Alves, Margarida, Distler, Oliver

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Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis von Lin, Neng-Yu, Distler, Alfiya, Beyer, Christian, Philipi-Schöbinger, Ariella, Breda, Silvia, Dees, Clara, Stock, Michael, Tomcik, Michal, Niemeier, Andreas, Dell'Accio, Francesco, Gelse, Kolja, Mattson, Mark P, Schett, Georg, Distler, Jörg HW

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