Harnessing the anti-cancer natural product nimbolide for targeted protein degradation von Spradlin, Jessica N., Hu, Xirui, Ward, Carl C., Brittain, Scott M., Jones, Michael D., Ou, Lisha, To, Milton, Proudfoot, Andrew, Ornelas, Elizabeth, Woldegiorgis, Mikias, Olzmann, James A., Bussiere, Dirksen E., Thomas, Jason R., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.

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Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex von Bussiere, Dirksen E., Xie, Lili, Srinivas, Honnappa, Shu, Wei, Burke, Ashley, Be, Celine, Zhao, Junping, Godbole, Adarsh, King, Dan, Karki, Rajeshri G., Hornak, Viktor, Xu, Fangmin, Cobb, Jennifer, Carte, Nathalie, Frank, Andreas O., Frommlet, Alexandra, Graff, Patrick, Knapp, Mark, Fazal, Aleem, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Beckwith, Rohan, Voshol, Hans, Wiesmann, Christian, Solomon, Jonathan M., Paulk, Joshiawa

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High-Confidence Protein–Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization von Proudfoot, Andrew, Bussiere, Dirksen E, Lingel, Andreas

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Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED von Li, Ling, Zhang, Hailong, Zhang, Man, Zhao, Mengxi, Feng, Lijian, Luo, Xiao, Gao, Zhenting, Huang, Ying, Ardayfio, Ophelia, Zhang, Ji-Hu, Lin, Ying, Fan, Hong, Mi, Yuan, Li, Guobin, Liu, Lei, Feng, Leying, Luo, Fangjun, Teng, Lin, Qi, Wei, Ottl, Johannes, Lingel, Andreas, Bussiere, Dirksen E, Yu, Zhengtian, Atadja, Peter, Lu, Chris, Li, En, Gu, Justin, Zhao, Kehao

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Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo von Dowdle, William E., Nyfeler, Beat, Nagel, Jane, Elling, Robert A., Liu, Shanming, Triantafellow, Ellen, Menon, Suchithra, Wang, Zuncai, Honda, Ayako, Pardee, Gwynn, Cantwell, John, Luu, Catherine, Cornella-Taracido, Ivan, Harrington, Edmund, Fekkes, Peter, Lei, Hong, Fang, Qing, Digan, Mary Ellen, Burdick, Debra, Powers, Andrew F., Helliwell, Stephen B., D’Aquin, Simon, Bastien, Julie, Wang, Henry, Wiederschain, Dmitri, Kuerth, Jenny, Bergman, Philip, Schwalb, David, Thomas, Jason, Ugwonali, Savuth, Harbinski, Fred, Tallarico, John, Wilson, Christopher J., Myer, Vic E., Porter, Jeffery A., Bussiere, Dirksen E., Finan, Peter M., Labow, Mark A., Mao, Xiaohong, Hamann, Lawrence G., Manning, Brendan D., Valdez, Reginald A., Nicholson, Thomas, Schirle, Markus, Knapp, Mark S., Keaney, Erin P., Murphy, Leon O.

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Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase von Lingel, Andreas, Sendzik, Martin, Huang, Ying, Shultz, Michael D, Cantwell, John, Dillon, Michael P, Fu, Xingnian, Fuller, John, Gabriel, Tobias, Gu, Justin, Jiang, Xiangqing, Li, Ling, Liang, Fang, McKenna, Maureen, Qi, Wei, Rao, Weijun, Sheng, Xijun, Shu, Wei, Sutton, James, Taft, Benjamin, Wang, Long, Zeng, Jue, Zhang, Hailong, Zhang, Maya, Zhao, Kehao, Lindvall, Mika, Bussiere, Dirksen E

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Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Syntha... von Wagman, Allan S, Boyce, Rustum S, Brown, Sean P, Fang, Eric, Goff, Dane, Jansen, Johanna M, Le, Vincent P, Levine, Barry H, Ng, Simon C, Ni, Zhi-Jie, Nuss, John M, Pfister, Keith B, Ramurthy, Savithri, Renhowe, Paul A, Ring, David B, Shu, Wei, Subramanian, Sharadha, Zhou, Xiaohui A, Shafer, Cynthia M, Harrison, Stephen D, Johnson, Kirk W, Bussiere, Dirksen E

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Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit von Ma, Xiaolei, Xie, Lili, Wartchow, Charles, Warne, Robert, Xu, Yongjin, Rivkin, Alexey, Tully, David, Shia, Steven, Uehara, Kyoko, Baldwin, Dianna M., Muiru, Gladys, Zhong, Weidong, Zaror, Isabel, Bussiere, Dirksen E., Leonard, Vincent H. J.

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A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses von Kane, Joshua R, Fong, Susan, Shaul, Jacob, Frommlet, Alexandra, Frank, Andreas O, Knapp, Mark, Bussiere, Dirksen E, Kim, Peter, Ornelas, Elizabeth, Cuellar, Carlos, Hyrina, Anastasia, Abend, Johanna R, Wartchow, Charles A

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Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex von Bussiere, Dirksen E., Xie, Lili, Srinivas, Honnappa, Shu, Wei, Burke, Ashley, Be, Celine, Zhao, Junping, Godbole, Adarsh, King, Dan, Karki, Rajeshri G., Hornak, Viktor, Xu, Fangmin, Cobb, Jennifer, Carte, Nathalie, Frank, Andreas O., Frommlet, Alexandra, Graff, Patrick, Knapp, Mark, Fazal, Aleem, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Beckwith, Rohan, Voshol, Hans, Wiesmann, Christian, Solomon, Jonathan M., Paulk, Joshiawa

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Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors von Ramurthy, Savithri, Pfister, Keith B., Boyce, Rustum S., Brown, Sean P., Costales, Abran Q., Desai, Manoj C., Fang, Eric, Levine, Barry H., Ng, Simon C., Nuss, John M., Ring, David B., Shafer, Cynthia M., Shu, Wei, Subramanian, Sharadha, Wagman, Allan S., Wang, Haixia, Bussiere, Dirksen E.

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Imaging Individual Molecular-Like Orbitals of a Non-Planar Naphthalene Diimide on Pt(111): A Combined STM and DFT Study von Ebeling, R, Tsukamoto, S, Dirksen, E, Caciuc, V, Müller, T. J. J, Atodiresei, N, Karthäuser, S

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Molecular Basis of mRNA Cap Recognition by Influenza B Polymerase PB2 Subunit von Xie, Lili, Wartchow, Charles, Shia, Steven, Uehara, Kyoko, Steffek, Micah, Warne, Robert, Sutton, James, Muiru, Gladys T., Leonard, Vincent H.J., Bussiere, Dirksen E., Ma, Xiaolei

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Targeting the Purinome von Murray, Jeremy M., Bussiere, Dirksen E.

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Intercellular Propagation of Calcium Waves Mediated by Inositol Trisphosphate von Boitano, Scott, Dirksen, Ellen R., Sanderson, Michael J.

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4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors von Ni, Zhi-Jie, Barsanti, Paul, Brammeier, Nathan, Diebes, Anthony, Poon, Daniel J., Ng, Simon, Pecchi, Sabina, Pfister, Keith, Renhowe, Paul A., Ramurthy, Savithri, Wagman, Allan S., Bussiere, Dirksen E., Le, Vincent, Zhou, Yasheen, Jansen, Johanna M., Ma, Sylvia, Gesner, Thomas G.

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Intercellular signaling in glial cells: Calcium waves and oscillations in response to mechanical stimulation and glutamate von Charles, Andrew C., Merrill, Jean E., Dirksen, Ellen R., Sandersont, Michael J.

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Mechanisms and function of intercellular calcium signaling von Sanderson, Michael J., Charles, Andrew C., Boitano, Scott, Dirksen, Ellen R.

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Intercellular Calcium Signaling via Gap Junctions in Glioma Cells von Charles, Andrew C., Christian C. G. Naus, Zhu, Daguang, Kidder, Gerald M., Dirksen, Ellen R., Sanderson, Michael J.

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Termination of DNA replication of bacterial and plasmid chromosomes von Bussiere, Dirksen E., Bastia, Deepak

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